Fat-suppressed Imaging

Fat-suppressed imaging is a magnetic resonance imaging technique that reduces signal from adipose tissue, improving the visibility of water-containing structures and abnormalities. It works by exploiting differences in the magnetic resonance behavior of fat and water: frequency-selective radiofrequency pulses, inversion-recovery sequences such as STIR, or chemical-shift methods attenuate fat signal before image readout. In biomedical and imaging engineering, fat suppression supports clearer assessment of edema, inflammation, tumors, cartilage, and soft-tissue injuries. Engineers use these methods to optimize pulse-sequence design, balance contrast with scan time, and reduce artifacts, strengthening MRI’s value in research, clinical diagnosis, and quantitative tissue characterization.

Fat-suppressed Imaging - Related Videos

Research

JoVE Journal - Medicine

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol

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Cited by 38 •

2018

The purpose of this work is to describe a protocol for creating a practical fat-water phantom that can be customized to produce phantoms with varying fat percentages and volumes.

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JoVE Journal - Medicine
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The Measurement and Treatment of Suppression in Amblyopia

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Cited by 55 •

2012

Amblyopia is a developmental disorder of the visual cortex that is often accompanied by strong suppression of one eye. We present a new technique for measuring and treating interocular suppression in patients with amblyopia that can be deployed using virtual reality goggles or a portable iPod Touch device.

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

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Cited by 35 •

2012

A method of functional imaging of mouse brown adipose tissue (BAT) is described in which cold-stimulated uptake of 18F-Fluorodeoxyglucose (FDG) in BAT is non-invasively assessed with a standardized micro-PET/CT protocol. This method is robust and sensitive to detect differences in BAT activities in mouse models.

Research

JoVE Journal - Medicine
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Transplantation Into the Mouse Ovarian Fat Pad

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Cited by 6 •

2016

We describe an ovarian fad pad transplantation assay suitable for studies of normal and transformed epithelia of the female reproductive tract. The mouse fat pad allows transplantation of large tissue fragments, is easily accessible for surgery and imaging, and provides the most favorable native environment for tissues of Müllerian origin.

Research

JoVE Journal - Medicine

A 3D Quantification Technique for Liver Fat Fraction Distribution Analysis Using Dixon Magnetic Resonance Imaging

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Cited by 1 •

2023

This study introduces a unique 3D quantification method for liver fat fraction (LFF) distribution using Dixon Magnetic Resonance Imaging (Dixon MRI). LFF maps, derived from in-phase and water-phase images, are integrated with 3D liver contours to differentiate LFF patterns between normal and steatotic livers, enabling precise assessment of liver fat content.

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