Fat-suppressed Imaging

Fat-suppressed imaging is a magnetic resonance imaging technique that reduces signal from adipose tissue, improving the visibility of water-containing structures and abnormalities. It works by exploiting differences in the magnetic resonance behavior of fat and water: frequency-selective radiofrequency pulses, inversion-recovery sequences such as STIR, or chemical-shift methods attenuate fat signal before image readout. In biomedical and imaging engineering, fat suppression supports clearer assessment of edema, inflammation, tumors, cartilage, and soft-tissue injuries. Engineers use these methods to optimize pulse-sequence design, balance contrast with scan time, and reduce artifacts, strengthening MRI’s value in research, clinical diagnosis, and quantitative tissue characterization.

Fat-suppressed Imaging - Related Videos

Research

JoVE Journal - Medicine
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The Measurement and Treatment of Suppression in Amblyopia

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Cited by 54 •

2012

Amblyopia is a developmental disorder of the visual cortex that is often accompanied by strong suppression of one eye. We present a new technique for measuring and treating interocular suppression in patients with amblyopia that can be deployed using virtual reality goggles or a portable iPod Touch device.

Research

JoVE Journal - Biology

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

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Cited by 37 •

2012

A method of functional imaging of mouse brown adipose tissue (BAT) is described in which cold-stimulated uptake of 18F-Fluorodeoxyglucose (FDG) in BAT is non-invasively assessed with a standardized micro-PET/CT protocol. This method is robust and sensitive to detect differences in BAT activities in mouse models.

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JoVE Journal - Medicine
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Transplantation Into the Mouse Ovarian Fat Pad

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Cited by 7 •

2016

We describe an ovarian fad pad transplantation assay suitable for studies of normal and transformed epithelia of the female reproductive tract. The mouse fat pad allows transplantation of large tissue fragments, is easily accessible for surgery and imaging, and provides the most favorable native environment for tissues of Müllerian origin.

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JoVE Journal - Medicine
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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography

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Cited by 26 •

2012

Fat content analysis is routinely conducted in studies utilizing murine obesity models. Emerging methods in small animal CT imaging and analysis are providing for longitudinal detail rich fat content analysis. Here we detail step by step procedures for performing small animal CT imaging, analysis, and visualization.

An Efficient Method to Obtain Dedifferentiated Fat Cells

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Cited by 4 •

2016

We have modified the conditions for DFAT cell generation and provide herein information regarding the use of an improved growth medium for the production of these cells.

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