Particle-in-cell Simulation

Particle-in-cell (PIC) simulation is a computational method for modeling systems in which charged particles interact through electromagnetic fields, making it valuable for analyzing complex plasma and engineering phenomena. The method represents particles individually or in representative groups while calculating electric and magnetic fields on a spatial grid; it then interpolates fields to particle locations, advances particle motion, and updates the fields repeatedly. PIC simulations can capture kinetic effects, collective behavior, wave-particle interactions, and instability development that continuum models may miss. Engineers use them to study plasma devices, particle accelerators, electric propulsion, fusion systems, and space environments, supporting design optimization and improved prediction of system performance.

Particle-in-cell Simulation - Related Videos

Research

JoVE Journal - Medicine

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model

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Cited by 3 •

2011

We demonstrate how to set up an in vitro ischemia/reperfusion model and how to evaluate the effect of stem cell therapy on postischemic cardiac cells.

Production and Collection of Pseudovirus Particles Using Mammalian Cell Culture

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2026

Source: Jamieson, T. R., et al. Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection. J. Vis. Exp. (2021)This video demonstrates the procedure for infecting mammalian cells with green fluorescent protein (GFP)-encoding pseudovirus, monitoring viral replication and spread by fluorescence microscopy, and collecting virus-containing supernatant for downstream applications.

Harvesting Hepatitis E Virus Particles from Human Liver Cancer Cells

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2026

Source: Meister, T. L., et al. A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks. J. Vis. Exp. (2020).This video demonstrates the process of isolating hepatitis E virus (HEV) particles from transfected human hepatocellular carcinoma cells. Extracellular viral particles are collected from filtered supernatants, while intracellular particles are released by subjecting the cells to repeated freeze-thaw cycles. The lysate is centrifuged, and the supernatant containing HEV...

Generation of Recombinant Viral Particles Using Embryonic Kidney Cells

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2026

Source: Vijayraghavan, S., Kantor, B. A Protocol for the Production of Integrase-deficient Lentiviral Vectors for CRISPR/Cas9-mediated Gene Knockout in Dividing Cells. J. Vis. Exp. (2017).This video demonstrates the procedure for generating recombinant viral particles by transfecting embryonic kidney cells with plasmids encoding viral proteins and a gene of interest.

Visualizing Hyporheic Flow Through Bedforms Using Dye Experiments and Simulation

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Cited by 4 •

2015

This manuscript describes how to create regular bedforms in a flume, visualize flow through the bedforms, and use computer simulations to simulate the hyporheic flow. The computer simulations compare well with the experimental observations. This coupled simulation and experiment is well-suited for both research and educational purposes.

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