Intravascular Ultrasound
Intravascular Ultrasound - Related Videos
09:43
In vivo Near Infrared Fluorescence (NIRF) Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
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Cited by 32 •
2011
We detail a new near-infrared fluorescence (NIRF) catheter for 2-dimensional intravascular molecular imaging of plaque biology in vivo. The NIRF catheter can visualize key biological processes such as inflammation by reporting on the presence of plaque-avid activatable and targeted NIR fluorochromes. The catheter utilizes clinical engineering and power requirements and is targeted for application in human coronary arteries. The following research study describes a multimodal imaging strategy...
10:53
A Novel Application of Musculoskeletal Ultrasound Imaging
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Cited by 14 •
2013
We describe a new ultrasound-based vector tissue Doppler imaging technique to measure muscle contraction velocity, strain and strain rate with sub-millisecond temporal resolution during dynamic activities. This approach provides complementary measurements of dynamic muscle function and could lead to a better understanding of mechanisms underlying musculoskeletal disorders.
04:40
Focus Ultrasound Based Microbubble Mediated Blood-Brain Barrier Opening: A Technique to Create Localized Transient Openings in Blood-Brain Barrier of Mouse by Sonoporation
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2025
This video describes a method of temporarily disrupting the blood-brain barrier (BBB) by creating transient openings using microbubble-mediated focused ultrasound (FUS). These transient local BBB openings can eventually be used to deliver larger-sized drug molecules directly into the brain parenchyma.
14:20
High-frequency Ultrasound Imaging of the Abdominal Aorta
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2023
Source: Amelia R. Adelsperger, Evan H. Phillips, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana High-frequency ultrasound systems are used to acquire high resolution images. Here, the use of a state-of-the-art system will be demonstrated to image the morphology and hemodynamics of small pulsatile arteries and veins found in mice and rats. Ultrasound is a relatively inexpensive, portable, and versatile method for the noninvasive...
05:51
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
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Cited by 18 •
2016
Here, we describe a simple method of intracerebroventricular and intravascular injection of viral particles or fluorescent microbeads into the neonatal mouse brain. The localization pattern of the virus and nanoparticles could be detected by microscopic evaluation or by in situ hybridization.
FAQs
A miniature transducer emits high-frequency sound waves into the vessel and detects the returning echoes. Differences in these echoes provide information about the lumen, vessel wall, and atherosclerotic plaque. Computer analysis organizes the signals into cross-sectional images, allowing clinicians to examine vascular structure from multiple positions as the catheter moves.
Angiography primarily depicts the vessel lumen, whereas Intravascular Ultrasound also shows structures within and beneath the vessel surface. This distinction helps identify plaque and characterize the vessel wall, even when the visible lumen does not fully represent the extent or arrangement of vascular disease. The added structural information supports more informed cardiovascular assessment.
IVUS can characterize atherosclerotic plaque while showing its relationship to the lumen and vessel wall. This cross-sectional perspective helps clinicians evaluate disease that may not be apparent from the vessel surface or lumen appearance alone. Plaque assessment therefore contributes to a more complete understanding of vascular structure during cardiovascular diagnosis and intervention.
The imaging process uses a catheter carrying a miniature ultrasound transducer inside the blood vessel. As the transducer moves through the vessel, it emits sound waves and receives returning echoes. A computer converts those signals into real-time images, enabling examination of vascular dimensions, the lumen, vessel wall, and plaque along the imaged segment.
Intravascular Ultrasound provides measurements of vessel dimensions and shows the relationship between the lumen, vessel wall, and plaque. Clinicians can use this information when planning and guiding stent placement, rather than relying only on the lumen appearance supplied by angiography. The structural measurements help support a more informed approach to vascular intervention.
After treatment, IVUS can be used to examine the restored vessel lumen and reassess surrounding vascular structure. Its images help clinicians determine whether treatment has adequately improved the lumen and how the result relates to the vessel wall and plaque. This post-intervention assessment adds structural information to evaluation of treatment outcome.