Intraventricular Balloon
Intraventricular Balloon - Related Videos
04:51
Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
0 Views •
2025
This video demonstrates a method to generate a rat model of neonatal intraventricular hemorrhage. In this procedure, an anesthetized rat pup is injected with hemoglobin into the lateral ventricle of the brain. The hemoglobin causes oxidative stress and releases heme, simulating intraventricular hemorrhage. The resulting damage to brain tissues, driven by reactive oxygen species and inflammatory cytokines, leads to ventricular enlargement, a common consequence of intraventricular hemorrhage.
07:57
Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
0 Views •
Cited by 12 •
2022
We present a model of neonatal intraventricular hemorrhage using rat pups that mimics the pathology seen in humans.
02:06
Inducing Brain Death in a Mouse Model Using a Balloon Catheter
0 Views •
2025
This video demonstrates the procedure for inducing brain death in a mouse model by increasing controlled intracranial pressure through a balloon catheter, mimicking natural brain death.
19:04
In Utero Intraventricular Injection and Electroporation of E16 Rat Embryos
0 Views •
Cited by 13 •
2007
In-utero in-vivo injection and electroporation of the embryonic rat neocortex provides a powerful tool for the manipulation of individual progenitors ...
08:42
A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics
0 Views •
Cited by 8 •
2016
The rat carotid balloon injury model described below allows researchers to evaluate drugs or therapeutics that negate injury-induced arterial hyperplasia. Detailed pre-surgical preparation, surgical procedure, and post-surgical cares of the animal are described.
FAQs
Inflation applies controlled expansion to a selected ventricular opening or passage. In an endoscopic third ventriculostomy, this enlargement can help establish or widen a route for cerebrospinal fluid drainage. The same device can also temporarily occlude a ventricular passage, giving the procedure a reversible way to manage fluid flow during treatment.
Balloon expansion must reach a defined size because excessive or poorly controlled dilation could affect nearby neural tissue, while inadequate expansion may fail to create a useful opening. Careful control links the mechanical action to the intended ventricular pathway and supports safer treatment when cerebrospinal fluid flow is obstructed.
Dilation enlarges a pathway, whereas temporary occlusion briefly blocks a ventricular passage. These opposing actions allow the device to support different procedural goals without requiring a separate mechanism for each task. Selecting the appropriate action depends on whether the immediate objective is improving cerebrospinal fluid passage or controlling flow during neurosurgical treatment.
The catheter is advanced into a brain ventricle under endoscopic or image-guided control. Once its position is confirmed, the balloon is inflated to a defined size for dilation or used to temporarily occlude a passage. After the intended effect is achieved, the device is managed within the procedure while placement and surrounding tissue remain under careful observation.
Endoscopic visualization or image-guided control helps direct the catheter through the ventricular system and position the balloon at the intended site. This guidance is important because the device acts within a confined space near neural tissue. Accurate placement supports the planned dilation or occlusion and helps limit unintended injury during the intervention.
Its use is particularly relevant when cerebrospinal fluid flow is blocked and pressure has increased because of hydrocephalus. During procedures such as endoscopic third ventriculostomy, balloon expansion can create or enlarge a drainage pathway. The intended outcome is improved fluid passage, while monitoring helps reduce the risk of damage to surrounding neural tissue.