Red-complex Organisms

Red-complex organisms are a group of anaerobic periodontal bacteria strongly associated with advanced periodontitis, making them important indicators of microbial imbalance and tissue-destructive inflammation. The group traditionally includes Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, which cooperate within subgingival biofilms through proteolytic activity, nutrient sharing, and disruption of host immune responses. Their combined activity can promote breakdown of periodontal connective tissue and alveolar bone, contributing to periodontal pocket formation and tooth loss. Identifying these organisms through microbial profiling supports research into disease mechanisms, diagnostic biomarkers, and targeted approaches for preventing or managing periodontal disease.

Red-complex Organisms - Related Videos

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JoVE Journal - Chemistry

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2016

A potential general method for the synthesis of water-soluble multimetallic peptidic arrays containing a predetermined sequence of metal centers is presented.

Education

JoVE Science Education - Chemistry

Coordination Chemistry Complexes

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2023

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2025

We describe a simple protocol for removing the statocyst and associated tissues in the ctenophore Mnemiopsis leidyi, which is amenable to live imaging.

Red Algae

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2025

Red algae, also known as rhodophytes, are primarily found in marine environments, though some species inhabit freshwater and terrestrial ecosystems. These organisms exist in both unicellular and multicellular forms, with some multicellular varieties reaching macroscopic sizes.As phototrophic organisms, red algae contain chlorophyll a; however, their chloroplasts lack chlorophyll b. Instead, they possess phycobiliproteins, which serve as major light-harvesting pigments, similar to those found in...

Protein Complexes with Interchangeable Parts

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2020

Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct. The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...

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