Centration

Centration is a cognitive tendency to focus on one prominent feature of a situation while overlooking other relevant features, a concept most closely associated with Jean Piaget’s account of preoperational thought. In developmental psychology, this process occurs when children attend to a single dimension, such as the height of a container, rather than coordinate multiple dimensions, such as height and width, when judging quantity. Centration helps explain young children’s difficulty with conservation tasks, including recognizing that an amount remains unchanged after its appearance shifts. Studying it clarifies changes in attention, reasoning, and logical thinking during cognitive development.

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Research

JoVE Journal - Biology

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy (iPALM)

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Cited by 10 •

2016

We present a protocol for the application of interferometric PhotoActivated Localization Microscopy (iPALM), a 3-dimensional single-molecule localization super resolution microscopy method, to the imaging of the actin cytoskeleton in adherent mammalian cells. This approach allows light-based visualization of nanoscale structural features that would otherwise remain unresolved by conventional diffraction-limited optical microscopy.

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