Vascular Dementia

Vascular dementia is a form of cognitive impairment caused by cerebrovascular disease, in which damaged blood vessels or reduced blood flow injure brain tissue and disrupt thinking, memory, and everyday functioning. It can develop after a stroke or through cumulative small-vessel damage, with the pattern and severity of symptoms depending on the brain regions and neural networks affected. Psychological assessment helps identify changes in executive function, attention, processing speed, mood, and behavior while distinguishing vascular contributions from other dementias. Understanding these mechanisms supports individualized cognitive rehabilitation, caregiver planning, and management of vascular risk factors, and informs research on how brain health influences cognition across aging.

Vascular Dementia - Related Videos

Research

JoVE Journal - Medicine

Using Retinal Imaging to Study Dementia

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Cited by 19 •

2017

The retina shares prominent similarities with the brain and thus represents a unique window to study vasculature and neuronal structure in the brain non-invasively. This protocol describes a method to study dementia using retinal imaging techniques. This method can potentially aid in diagnosis and risk assessment of dementia.

Education

JoVE Core - Introduction to Psychology

Dementia

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2025

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging. The progression of dementia is generally gradual.

Dementia l: Introduction

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2026

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

Research

JoVE Journal - Behavior
Free Sample

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

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Cited by 68 •

2016

This article describes the 4 Mountains Test (4MT), a hippocampus-dependent test of working allocentric spatial memory. The hippocampus is affected early in Alzheimer's disease (AD) and this article outlines the 4MT methodology and results of patient testing, which demonstrates the value of the 4MT in the diagnosis of pre-dementia AD.

Research

JoVE Journal - Neuroscience
Free Sample

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis

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Cited by 2 •

2024

The needle method of asymmetric bilateral common carotid artery stenosis is proposed to create a mouse model for vascular cognitive impairment and dementia. It results in longer-term outcomes compared to previously established models and is compatible with live MRI. Visual representation demonstrating the procedure provides guidance for mastering the surgery.

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