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JoVE Journal Behavior
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
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Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

Article DOI: 10.3791/51524-v • 12:18 min • April 23rd, 2015
April 23rd, 2015 •
1, 2, 2, 2, 2, 3
1Department of Psychiatry and Behavioral Neurosciences, McMaster University, 2Department of Psychology, Neuroscience & Behaviour, McMaster University, 3Neuroscience Program, McMaster University

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Automatic Translation

Prolonged and comprehensive monitoring of mice in a home-cage environment provides a deeper understanding of aberrant behavior in murine models of brain diseases. This paper describes the Integrated Behavioral Station (INBEST) as the key component of contemporary behavioral analysis.

Tags

Behavioral Phenotyping Murine Disease Models Integrated Behavioral Station INBEST Genetic Engineering Small Rodents Biomedical Research Chronic CNS Disorders Behavioral Level Pathogenic Mechanisms Functional Deficits Peripheral Pathology Battery Of Tests Video-tracking Behavioral Spectroscopy Physiological Measures Home-base-like Setting Phenotyping Protocol Monitoring Apparatus Basic Functional Outputs Spontaneous Activity Food/water Intake Motivated Behavior Stress-free Environment Reproducibility Standardization
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