Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

Cassandra L. Taylor; Yuri Bolshan

doi:10.3791/52401

Journal

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化学

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Ynones从酰氯和钾Alkynyltrifluoroborate盐无金属合成

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

JoVE 杂志
化学

This content is Free Access.

JoVE 杂志化学

Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

Ynones从酰氯和钾Alkynyltrifluoroborate盐无金属合成

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11,127 Views

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09:58 min

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February 24, 2015

DOI:

10.3791/52401-v

DOI:

10.3791/52401-v

•

09:58 min

February 24, 2015

•

3 Views

Cassandra L. Taylor¹, Yuri Bolshan¹

¹Faculty of Science,University of Ontario Institute of Technology

Summary

The goal of this manuscript is to demonstrate a straightforward method for the preparation of ynones from acyl chloride and potassium alkynyltrifluoroborate salt starting materials. The one-pot reaction proceeds rapidly in the presence of boron trichloride without exclusion of air and moisture.