Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Natalie L. Leong; Nima Kabir; Armin Arshi; Azadeh Nazemi; Ben M. Wu; David R. McAllister; Frank A. Petrigliano

doi:10.3791/52797

Journal

/

生物工程

/

无胸腺大鼠模型工程前交叉韧带移植评估

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

JoVE 杂志
生物工程

需要订阅 JoVE 才能查看此. 登录或开始免费试用。

JoVE 杂志生物工程

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

无胸腺大鼠模型工程前交叉韧带移植评估

Please note that all translations are automatically generated. Click here for the English version.

10,269 Views

•

10:32 min

•

March 26, 2015

DOI:

10.3791/52797-v

DOI:

10.3791/52797-v

•

10:32 min

March 26, 2015

•

6 Views

Natalie L. Leong¹, Nima Kabir¹, Armin Arshi¹, Azadeh Nazemi², Ben M. Wu², David R. McAllister¹, Frank A. Petrigliano¹

¹Department of Orthopaedic Surgery,University of California Los Angeles, ²Department of Bioengineering,University of California Los Angeles

Summary

Animal models are important tools for the evaluation of tissue-engineered grafts. This paper presents the protocol for preparing an electrospun biodegradable polymer graft for use in anterior cruciate ligament tissue engineering, as well as a surgical protocol for implantation in a rat model.