Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

Fitz-Roy E. Curry; Joyce F. Clark; Roger H. Adamson

doi:10.3791/53210

Journal

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生物学

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微灌技术在调查微血管渗透性的大鼠肠系膜条例

Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

JoVE 杂志
生物学

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JoVE 杂志生物学

Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

微灌技术在调查微血管渗透性的大鼠肠系膜条例

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9,669 Views

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12:48 min

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September 12, 2015

DOI:

10.3791/53210-v

DOI:

10.3791/53210-v

•

12:48 min

September 12, 2015

•

7 Views

Fitz-Roy E. Curry¹, Joyce F. Clark¹, Roger H. Adamson¹

¹Department of Physiology & Membrane Biology,University of California Davis

Summary

The modified Landis technique enables paired measurement of the hydraulic conductivity of individual microvessels in the mesentery of normal and genetically modified rats under control and test conditions using microperfusion techniques. It provides a convenient method to evaluate mechanisms that regulate microvessel permeability and transvascular exchange under physiological conditions.