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A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS

Article DOI: 10.3791/53257-v • 06:49 min • October 6th, 2015
October 6th, 2015 •
1, 1, 1, 1, 1, 1
1ALS Therapy Development Institute

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This video protocol describes a sensitive, reliable, and quick method for evaluating the neuromuscular deficits in a transgenic mouse model of amyotrophic lateral sclerosis.

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Phenotypic Neurological Scoring System Disease Progression SOD1-G93A Mouse Model Amyotrophic Lateral Sclerosis (ALS) Phenotypic Screening Protocol Neuromuscular Function Hindlimb Function NeuroScore Paresis Paralysis Drug-induced Changes Scoring Ambiguities Inter-experimenter Variability Video Protocol ALS Researchers
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