Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori

Stem cell derived cultures harbor tremendous potential to model infectious diseases. Here, the culture of mouse and human gastric organoids derived from adult stem cells is described. The organoids are microinjected with the gastric pathogen Helicobacter pylori.

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Organoids Model Infectious Diseases Culture Human Murine Stomach Organoids Microinjection Helicobacter Pylori Infection Biologists Stem Cells Embryonic Stem Cells Induced Pluripotent Stem Cells Adult Stem Cells Gastric Glands Basement Matrix Growth Factors Epidermal Growth Factor (EGF) R-spondin Noggin Wnt Fibroblast Growth Factor (FGF) 10 Gastrin Transforming Growth Factor (TGF) Beta Inhibitor 3-dimensional Organoids Lineages Of The Stomach Indefinitely Expandable Organoids Frozen And Thawed Organoids Bacteria Infection Studies

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Journal (Immunology and Infection)

Journal (Immunology and Infection)

Organoids as Model for Infectious Diseases: Culture of Human and Murine Stomach Organoids and Microinjection of Helicobacter Pylori

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