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In Vivo Biosensor Tracks Icke-apoptotiska kaspasaktivitet i Drosophila

Article DOI: 10.3791/53992-v • 13:21 min • November 27th, 2016
November 27th, 2016 •
1, 1, 2, 1
1W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, 2School of Life Sciences, Chinese University of Hong Kong

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För att detektera friska celler i hela djur som innehåller låga halter av kaspas-aktivitet, var mycket känsliga biosensorn betecknad CaspaseTracker genereras för Drosophila. Kaspas-beroende biosensor aktivitet upptäcks i långlivade friska celler genom de inre organen av vuxna djur som fötts upp under optimerade betingelser i frånvaro av döds stimuli.

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Molecular Biology Caspase biosensor, apoptos icke-apoptotiska hjärna neuron CaspaseTracker
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