Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis

Hollie Burrell-Saward; Theresa H. Ward

doi:10.3791/54032

Journal

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免疫与感染

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生物发光成像检测到非洲锥虫病的晚期感染

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis

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免疫与感染

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JoVE 杂志免疫与感染

Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis

生物发光成像检测到非洲锥虫病的晚期感染

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7,749 Views

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07:59 min

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May 18, 2016

DOI:

10.3791/54032-v

DOI:

10.3791/54032-v

•

07:59 min

May 18, 2016

•

7736 Views

Hollie Burrell-Saward¹, Theresa H. Ward¹

¹Department of Infection and Immunity,London School of Hygiene & Tropical Diseases

Summary

This manuscript describes the use of a bioluminescent strain of African trypanosomes to enable the tracking of late stage infection and demonstrates how in vivo live imaging can be used to visualize infections within the central nervous system in real-time.