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Bioengineering
磁悬浮加上便携式成像与分析诊断疾病
磁悬浮加上便携式成像与分析诊断疾病
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

磁悬浮加上便携式成像与分析诊断疾病

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07:42 min
February 19, 2017

DOI: 10.3791/55012-v

Stephanie M. Knowlton1, Bekir Yenilmez2, Reza Amin2, Savas Tasoglu1,2

1Biomedical Engineering Department,University of Connecticut, 2Mechanical Engineering Department,University of Connecticut

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Please note that some of the translations on this page are AI generated. Click here for the English version.

我们提出了一种磁悬浮技术,并在智能手机兼容设备和具有嵌入式成像和处理的设备中结合了自动成像和分析。这适用于测量细胞的密度分布,具有两个已证明的生物医学应用:镰状细胞病诊断和分离白细胞和红细胞。

该过程的总体目标是通过测量细胞群分布的改变或根据细胞的特征密度分离细胞类型,为各种医学诊断应用进行基于密度的细胞分析。该方法可以帮助解决生物医学工程中的关键挑战,即在临床环境或发展中国家进行重要的 Cell WAYS 医学诊断。这种技术的主要优点是它不需要很多设备或准备工作,几乎任何人都可以完成。

该技术的意义延伸到镰状细胞诊断,因为该设备可以量化镰状细胞中低氧条件引起的密度增加和悬浮速率降低。虽然这种方法对医学诊断测试很有用,如此处所示,但它也可以通过改变样品和修改软件应用于其他基于密度的细胞术测试。首先,准备 10 毫升 50 毫摩尔的钆布特醇和 Hanks 平衡盐溶液。

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