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Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary

Article DOI: 10.3791/55082-v • 14:54 min • January 16th, 2017
January 16th, 2017 •
*1, *1, 1, 1, 1
1Unidad de Investigación y Desarrollo, Probiomed S.A. de C.V.
* These authors contributed equally

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Here, we present a comprehensive capillary zone electrophoresis protocol for the assessment of intrinsic physicochemical heterogeneity of monoclonal antibodies as a quality attribute.

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Capillary Electrophoresis Monoclonal Antibody Isoforms Neutral Capillary Bio-molecules Analysis Sample Preparation System Preparation Method Setup Data Processing Analytical Chemistry Laboratories HPMC Concentration Elastic Polymer Glass Beaker Water Rinsing PH Adjustment Solution Stabilization
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