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Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT

Article DOI: 10.3791/55184-v • 07:07 min • May 2nd, 2017
May 2nd, 2017 •
1, 2,3,4,5, 6, 4,5, 7, 4,5, 4,5, 1,5, 1,5
1School of Medical Sciences, Faculty of Medicine, UNSW Australia, 2Department of Nuclear Medicine, Concord Hospital, 3National Imaging Facility, University of Sydney, 4Brain and Mind Centre, University of Sydney, 5Faculty of Health Sciences, University of Sydney, 6Life Sciences, ANSTO, 7CERMEP

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This study describes a protocol that uses 18F-FDG and positron emission tomography/computed tomography (PET/CT) imaging, together with kinetic modelling, to quantify the in vivo, real-time uptake of 18F-FDG into tissues.

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Glucose Metabolism Kinetics 18F-FDG Micro-PET/CT In Vivo Real-time Uptake Glucose Bloodstream Specific Tissues Mice Diabetes Metabolism Field Diabetic Treatments Longitudinal Experiments Age Impact Diet Impact Glucose Metabolism In Sclero Muscle Liver Brain Rats Visual Demonstration Imaging Acquisition Analysis Steps Accurate Results Induction Chamber Imaging Bed Heat Pad 80% Ethanol Wipe Down Anesthetize Mouse With 5% Isoflurane And Oxygen Electric Heating Pad Sensor Pad Prone Position For Mouse One Liter Per Minute Of 1.5 To 2% Isoflurane By Nose Cone Veterinary Ointment For Eyes Dryness Prevention Warm Mouse's Tail For One To Two Minutes Dilated Lateral Tail Vein
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