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基于荧光的淋巴细胞检测适用于小分子的高通量筛选

A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

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A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

基于荧光的淋巴细胞检测适用于小分子的高通量筛选

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10,267 Views

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08:43 min

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March 10, 2017

DOI:

10.3791/55199-v

DOI:

10.3791/55199-v

•

08:43 min

March 10, 2017

•

3 Views

Ahmed Fouda¹, Mahasti Tahsini², Fatemeh Khodayarian², Fatimah Al-nafisah², Moutih Rafei^1,2,3

¹Department of Microbiology, Infectiology and Immunology,Université de Montréal, ²Department of Pharmacology and Physiology,Université de Montréal, ³Molecular Biology Program,Université de Montréal

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Summary

我们提出在目前的研究使用从转基因小鼠衍生的淋巴细胞的新颖的基于荧光的测定法。该测定是适于赋予的任抑制或促进淋巴细胞的活化的能力的小分子的高通量筛选（HTS）。

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