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全身麻醉下小鼠幸福度的系统评价

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia

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行为学

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JoVE 杂志行为学

Systematic Assessment of Well-Being in Mice for Procedures Using General Anesthesia

全身麻醉下小鼠幸福度的系统评价

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12,086 Views

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06:50 min

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March 20, 2018

DOI:

10.3791/57046-v

DOI:

10.3791/57046-v

•

06:50 min

March 20, 2018

•

12 Views

Katharina Hohlbaum^1,2, Bettina Bert^2,3, Silke Dietze², Rupert Palme⁴, Heidrun Fink², Christa Thöne-Reineke¹

¹Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Department of Veterinary Medicine,Freie Universität Berlin, ²Institute of Pharmacology and Toxicology, Department of Veterinary Medicine,Freie Universität Berlin, ³German Federal Institute for Risk Assessment (BfR), ⁴Unit of Physiology, Pathophysiology and Experimental Endocrinology, Department of Biomedical Sciences,University of Veterinary Medicine

成績單

Summary

我们制定了一个协议, 以评估小鼠的福祉在程序中使用全麻。分析了一系列的行为参数, 说明了幸福水平和糖皮质激素代谢产物。该议定书可作为一般援助, 以科学的、以动物为中心的方式估计严重程度。

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