Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets <em>via </em>Semi-3-Dimensional Flow Focusing Microfluidic Devices

Yan Wu; Xiang Qian; Shengli Mi; Min Zhang; Shuqing Sun; Xiaohao Wang

doi:10.3791/57198

Semi-3-Dimensional 流聚焦微流控装置产生尺寸控制的聚乙二醇二丙烯酸酯液滴

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Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices

Semi-3-Dimensional 流聚焦微流控装置产生尺寸控制的聚乙二醇二丙烯酸酯液滴

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11:08 min

July 3, 2018

DOI: 10.3791/57198-v

Yan Wu¹, Xiang Qian¹, Shengli Mi¹, Min Zhang¹, Shuqing Sun¹, Xiaohao Wang^1,2

¹Graduate School at Shenzhen,Tsinghua University, ²The State Key Laboratory of Precision Measurement Technology and Instruments,Tsinghua University

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在这里, 我们提出了一个协议来说明一个半三维 (semi-3D) 流聚焦微流控芯片的形成过程和验证实验。

该方法有助于回答微流控液滴形成领域的关键问题，包括制造半三维流聚焦 PDMS 芯片和生产纯 PGD 液滴。这种策略的主要优点是半 3D 流聚焦装置为流聚焦模具提供了更大的测试场地。纯 PGD 确保 PGD 颗粒的比率低于 10%由于更大的表面积与体积比，该技术的含义可以扩展到许多生化含义。

喷嘴，大规模应用将有利于这种技术，消耗几微升样品。现在，这种方法可以提供对 PGD 液滴形成的见解。它也可以应用于其他系统，例如配备气体的流动聚焦分析。

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