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JoVE Journal
Bioengineering
脱碳软骨衍生基质支架的制备
脱碳软骨衍生基质支架的制备
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Fabrication of Decellularized Cartilage-derived Matrix Scaffolds

脱碳软骨衍生基质支架的制备

Full Text
11,521 Views
08:02 min
January 7, 2019

DOI: 10.3791/58656-v

Kim E.M. Benders1, Margo L. Terpstra1, Riccardo Levato1, Jos Malda1,2

1Department of Orthopedics,University Medical Center Utrecht, The Netherlands, 2Department of Veterinary Medicine, Equine Surgery,University of Utrecht, The Netherlands

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Please note that some of the translations on this page are AI generated. Click here for the English version.

脱形软骨衍生支架可用作指导软骨修复的支架, 也可用作骨软骨组织再生的手段。本文详细介绍了脱髓化过程, 并对在体外环境中使用这些支架提出了建议。

此方法提供了一种从原生组织中提取的脚手架,可用于软骨再生的方法。该技术的主要优点是,原生软骨的成分保留在脚手架中,可以促进软骨形成和体外和体内再生。虽然这些方法使用软骨从马窒息关节,软骨从任何其他关节也可以使用。

首先,获得一个完整的尸体关节软骨分离,并删除皮肤多余的脂肪和肌肉组织,如随附的文本协议所述。接下来,定义关节通过执行关节的延伸拐点来表达的位置。做一个水平切口,以达到关节腔。

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