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DOI: 10.3791/58934-v
Aida Llucià-Valldeperas1,2, Ramon Bragós3, Antoni Bayés-Genís1,4,5,6
1Insuficiencia Cardiaca y Regeneración Cardiaca (ICREC) Research Program,Health Science Research Institute Germans Trias i Pujol, 2Amsterdam Universitair Medisch Centrum (UMC), Vrije Universiteit Amsterdam, Pulmonology and Physiology,Amsterdam Cardiovascular Sciences, 3Electronic and Biomedical Instrumentation Group, Departament d'Enginyeria Electrònica,Universitat Politècnica de Catalunya, 4Cardiology Service,Germans Trias i Pujol University Hospital, 5Department of Medicine,Universitat Autònoma de Barcelona, 6Centro de Investigación Biomédica en Red (CIBER) Cardiovascular,Instituto de Salud Carlos III
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This article presents a method for applying electromechanical stimulation to cells, enhancing their cardiomyogenic potential. This technique has applications in cell therapy, disease modeling, and drug screening.
在这里, 我们提出了一个协议, 训练细胞群使用电子和机械刺激模拟心脏生理。这种机电刺激增强了治疗细胞的心肌潜能, 是进一步进行细胞治疗、疾病建模和药物筛选的有希望的策略。
这是一种在细胞上应用机电刺激的方法。它有多种应用来研究它对细胞种群的影响,对体内分娩的预训练,以及细胞成熟。其优点是,电气和机械刺激可以单独或同时与同一设备一起应用,同时保持无菌病毒完好无损。
这种技术是我们治疗的间接方法。细胞疗法被认为是机电刺激细胞可能是一个有趣的细胞群体,以治疗内向心肌。该方法一般属于心血管领域,但也可以应用于神经系统。
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