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Journal / Cancer Research / 三维流状入侵检测中的全人肿瘤基基质…
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Cancer Research

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JoVE Journal Cancer Research
三维流状入侵检测中的全人肿瘤基基质
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三维流状入侵检测中的全人肿瘤基基质

Article DOI: 10.3791/59567-v • 08:15 min • May 7th, 2019
May 7th, 2019 •
1, 1, *1, *1, 1, 1, 1,2,3,4
1Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, 2Cancer and Translational Medicine Research Unit, University of Oulu, 3Medical Research Center, Oulu University Horspital, 4Helsinki University Hospital
* These authors contributed equally

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肿瘤微环境是癌症生长和侵袭的重要组成部分。为了模仿癌症的进展, 需要一个与生物学相关的人类基质。该方案介绍了应用人平滑肌瘤基基质进行体外三维球体入侵检测的改进。该协议还介绍了基于计算机的细胞入侵分析。

Tags

癌症研究 第147期 肿瘤微环境 成像 癌症 斐济 ImageJ ilastik 人类肌瘤衍生基质 纤维蛋白 小鼠肉瘤衍生基质 胶原蛋白
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