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A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression

Article DOI: 10.3791/59676-v • 07:23 min • September 13th, 2019
September 13th, 2019 •
1, 2, 1, 3,4
1Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, 2Department of Physiology and Pharmacology, Karolinska Institutet, 3Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, 4Nebraska Center for Materials and Nanoscience, University of Nebraska-Lincoln

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This article provides detailed methods for fabricating and characterizing a pneumatically actuating microfluidic device for chondrocyte compression.

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Microfluidic Platform Stimulating Chondrocytes Dynamic Compression Pneumatically Activated Device Mechanobiology 3D Hydrogel Cultures Cost-effective Time-effective Multiple Magnitudes Of Compression Microscopic Imaging PDMS Microchannel Layer Mold Degassing Transparency Film Glass Plate Plasma Cleaner Bonding Thin PDMS Membrane Spin Coating
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