Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Jes&#250;s Espada; Elisa Carrasco; Mar&#237;a  I. Calvo-S&#225;nchez; Sandra Fern&#225;ndez-Martos; Juan  Jos&#233; Montoya

doi:10.3791/60859

Journal

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生物学

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通过可切换原卟啉IX依赖性原位活性氧物种光生成刺激小鼠皮肤中的干细胞壁龛和组织再生

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

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生物学

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JoVE 杂志生物学

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

通过可切换原卟啉IX依赖性原位活性氧物种光生成刺激小鼠皮肤中的干细胞壁龛和组织再生

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1,901 Views

•

10:05 min

•

May 08, 2020

DOI:

10.3791/60859-v

DOI:

10.3791/60859-v

•

10:05 min

May 08, 2020

•

1889 Views

Jesús Espada^1,2, Elisa Carrasco³, María I. Calvo-Sánchez^1,4, Sandra Fernández-Martos¹, Juan José Montoya⁵

¹Ramón y Cajal Institute for Health Research (IRYCIS),Ramón y Cajal University Hospital ²Centro Integrativo de Biología y Química Aplicada (CIBQA),Universidad Bernardo O’Higgins ³Department of Molecular Biology, Faculty of Sciences,Universidad Autónoma de Madrid (UAM)⁴Instituto de Investigaciones Biosanitarias, Facultad de Ciencias Experimentales,Universidad Francisco de Vitoria ⁵Department of Radiology, Rehabilitation & Physiotherapy, Faculty of Medicine,Complutense University

Summary

该协议的目的是诱导小鼠皮肤中瞬时体内产生非致死水平的活性氧（ROS），进一步促进组织中的生理反应。

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通过可切换原卟啉IX依赖性原位活性氧物种光生成刺激小鼠皮肤中的干细胞壁龛和组织再生

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