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JoVE Journal
Immunology and Infection
噬菌体纤维化 斑马鱼胚 胎中伪多多多阿韦诺萨感染的噬菌体治疗应用
噬菌体纤维化 斑马鱼胚 胎中伪多多多阿韦诺萨感染的噬菌体治疗应用
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos

噬菌体纤维化 斑马鱼胚 胎中伪多多多阿韦诺萨感染的噬菌体治疗应用

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7,027 Views
11:20 min
May 12, 2020

DOI: 10.3791/61275-v

Marco Cafora1,2, Francesca Forti3, Federica Briani3, Daniela Ghisotti3, Anna Pistocchi2

1Dipartimento di Scienze Cliniche e Comunità,Università degli Studi di Milano, 2Dipartimento di Biotecnologie Mediche e Medicina Traslazionale,Università degli Studi di Milano, LITA, 3Dipartimento di Bioscienze,Università degli Studi di Milano

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Please note that some of the translations on this page are AI generated. Click here for the English version.

这里介绍的是伪 多多多酸菌感染和 噬菌体治疗应用囊性纤维化(CF)斑马鱼胚胎的协议。

该协议有助于制备和管理病毒和噬菌体鸡尾酒,以对抗斑马鱼胚胎中的伪单体亚鲁吉诺萨。这种技术的主要优点是,它允许在体内评估噬菌体在对抗细菌感染的功效。噬菌体鸡尾酒在野生型和囊性纤维化斑马鱼模型中都非常有效。

为囊性纤维化患者的细菌感染提供噬菌体治疗的可能性。噬菌体疗法也可以用于抵消其他模型系统中的特定细菌感染。为实验准备噬菌的植物。

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