JoVE Journal
Immunology and Infection
Immunology and Infection
需要订阅 JoVE 才能查看此 内容. 登录或开始免费试用。
章节
总结概括
Infection of neonatal mice with bioluminescent E. coli O1:K1:H7 results in a septic infection with significant pulmonary inflammation and lung pathology. Here, we describe procedures to model and further study neonatal sepsis using longitudinal intravital imaging in parallel with enumeration of systemic bacterial burdens, inflammatory profiling, and lung histopathology.