利用单细胞RNA测序和单细胞ATAC测序对视网膜基因表达与染色质可及性进行多重分析
3.7K 次观看
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被引用 9 次
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06:24 分钟
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2021年3月12日
DOI :10.3791/62239-v
2021年3月12日
•3.7K 次观看
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally
在此，作者展示了MULTI-seq在表型分析及后续配对的单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）中的应用价值，用于表征视网膜中的转录组和染色质可及性谱型。
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Chapters in this video
0:04
Introduction
0:47
Cell Barcoding
3:23
Paired scRNA-seq and scATAC-seq
4:40
Results: Multiplexed Analysis Using scRNA-Seq and scATAC-Seq for Characterization of Cell Origin, Phenotype and Gene Regulatory Networks
5:45
Conclusion
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