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Handling Techniques to Reduce Stress in Mice

Article DOI: 10.3791/62593-v • 09:03 min • September 25th, 2021
September 25th, 2021 •
1, 1,2, 3, 4, 5, 1,2,3, 1,2
1Campbell Family Mental Health Research Institute of CAMH, 2Department of Psychiatry, University of Toronto, 3Department of Pharmacology and Toxicology, University of Toronto, 4Departamento de Investigación, Universidad Central de Queretaro, 5Centre National de la Recherche Scientifique, UMR 5287, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, Université de Bordeaux

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This paper describes a handling technique in mice, the 3D-handling technique, which facilitates routine handling by reducing anxiety-like behaviors and presents details on two existing related techniques (tunnel and tail handling).

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Handling Techniques Reduce Stress Mice Dr. Thomas Prevot Center For Addiction And Mental Health (CAMH) University Of Toronto Department Of Psychiatry Baseline Anxiety Reactivity Data Variability Animal Welfare Environmental Variables Housing Conditions Environmental Enrichment Stress Exposure Tail Handling Tunnel Handling Cup Handling 3D Handling
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