利用多功能系统对人癌细胞和正常细胞中Yes相关蛋白进行全光学机械生物学研究
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被引用 4 次
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09:55 分钟
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2021年12月20日
DOI :10.3791/62934-v
2021年12月20日
•5K 次观看
Qin Luo*1 , Miao Huang*2 , Chenyu Liang2 , Justin Zhang3 , Gaoming Lin1 , Sydney Yu1 , Mai Tanaka4,5 , Sharon Lepler4,5 , Juan Guan5,6,7 , Dietmar Siemann4,5 , Xin Tang2,5
1Department of Electrical and Computer Engineering, Herbert Wertheim College of Engineering, University of Florida, 2Department of Mechanical and Aerospace Engineering, Herbert Wertheim College of Engineering, University of Florida, 3Department of Electrical and Computer Engineering, University of California, 4Department of Radiation Oncology, College of Medicine, University of Florida, 5UF Health Cancer Center, University of Florida, 6Department of Physics, College of Liberal Arts and Sciences, University of Florida, 7Department of Anatomy and Cell Biology, College of Medicine, University of Florida
* These authors contributed equally
本文介绍了一种详细的逐步实验方案，阐述如何利用一种集成的多功能且用户可编程的系统，实现自动化的多通道成像和力学-生物学分析，以阐明Yes相关蛋白（YAP）的力学敏感性。
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Chapters in this video
0:04
Introduction
0:53
Cell Imaging
7:21
Results: All-Optical Mechanobiology Interrogation of Yes-Associated Protein in Human Cancer and Normal Cells
9:11
Conclusion
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