2022年5月5日
The present protocol describes how a 10-0 polypropylene suture crosses the anterior surface of the iris, forming a pentagram to prevent both iris and pupil from moving toward the cornea. This can be combined with subsequent keratoplasty to cure bullous keratopathy with extensive anterior synechia of the iris.
The pentagram suturing anterior chamber plasty, or PSACP, provides an adequate space basis for DSAEK to help cure the bullous keratopathy caused by a vanished anterior chamber or extensive anterior synechia. Begin by displaying the range of anterior synechia by ASOCT and UBM to design the position of incisions. Mark the five scleral puncture points 1.5 millimeters posterior to the limbus with 1%crystal violet solution.
After ensuring that the circular distance between the adjacent puncture points is 72 degrees, remove the edematous epithelium of the cornea with a sclera tunnel knife. Make a one millimeter limbus incision and inject cohesive viscoelastic to separate the anterior synechia of the iris. Perform blunt separation for PAS.
Insert the 16 millimeter STC-6 needle one millimeter beside one of the puncture points into the anterior chamber and retrieve it across the surface of the iris within the bore of a 29 gauge syringe from another puncture point with a circular distance of 144 degrees. When the STC-6 needle comes out of the anterior chamber, select the next insertion point. Repeat this process until the retention sutures in the anterior chamber form a pentagram-like barrier on the surface of the iris and pupil.
Tie a surgical knot from the initial insertion point and embed it into the superficial sclera under the bulbar conjunctiva. In the first case study without PSACP one day post-anterior chamber plasty with synechia separation and PKP, the 68-year-old female showed no PAS with the ASOCT and BCVA improved to 20/1000 with elevated IOP. 12 weeks after surgery, the patient showed 360 degrees PAS with the UBM and BCVA decreased to 20/1600.
The IOP was uncontrolled over 25 millimeters of mercury and the bullous keratopathy reoccurred. In the second case study, a 75-year-old female received PSACP where pentagram sutures were placed as a barrier in front of the anterior surface of the iris. No PAS was seen with ASOCT or UBM until 12 weeks post-surgery.
In 24 weeks post DSAEK and PSACP, no corneal edema was observed and one clock hour PAS was demonstrated with UBM, with BCVA 20/66. IOP remained normal without any medication post-surgery. In the third case study, a 69-year-old female received PSACP and showed two clock hours PAS with ASOCT on day one post-surgery.
The patient showed six clock hours PAS with UBM in 24 weeks post-surgery and received PKP. On one week post PKP, mild edema was seen in the cornea graft and six clock hours PAS with the ASOCT with improved BCVA 20/400. IOP remained normal without any medication post-surgery.
Ensure that the adjacent puncture points are at a circular distance of 72 degrees and that puncture points are 1.5 millimeters posterior to the limbus without touching the anti-glaucoma filtration bleb. Iris fixation via PSACP utilizes only one 10-0 proline suture to form a stable anterior chamber with adequate spaces for over a month. This can be followed up with DSAEK or PKP for treating bullous keratopathy with extensive anterior synechia of the iris.
本方案概述了使用10-0聚丙烯缝线进行五角缝合前房成形术(PSACP)的技术,以稳定虹膜和瞳孔。该方法旨在治疗与广泛性前粘连相关的水疱性角膜病变。
对于存在广泛前粘连的眼部,稳定前房结构对于实施后续角膜干预措施以及降低复发性大泡性角膜病变的风险至关重要。五角星缝合前房成形术(PSACP)技术提供了一种可重复的方法,用于维持前房解剖结构,支持复杂眼科病例中的手术规划及临床转化的连续性。该方法解决了需要进行内皮角膜移植术(DSAEK)或穿透性角膜移植术(PKP)患者在外科治疗流程中的一个关键转折点。
PSACP 位于外科发现与临床前验证的交汇点,能够为前房重建提供强有力的假设检验和工作流程标准化。