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Medicine
微型猪:人工耳蜗研究的大型动物模型
微型猪:人工耳蜗研究的大型动物模型
JoVE Journal
Medicine
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JoVE Journal Medicine
The Miniature Pig: A Large Animal Model for Cochlear Implant Research

微型猪:人工耳蜗研究的大型动物模型

Full Text
3,706 Views
06:16 min
July 28, 2022

DOI: 10.3791/64174-v

Xiaojun Ji*1,2,3,4, Yi Luo*1,2,3,4, Weiwei Guo1,2,3,4, Fei Ji1,2,3,4, Shuolong Yuan1,2,3,4, Liangwei Xu1,2,3,4, Wei Chen*1,2,3,4

1College of Otolaryngology Head and Neck Surgery,Chinese PLA General Hospital, 2National Clinical Research Center for Otolaryngologic Diseases, 3Key Lab of Hearing Science,Ministry of Education, 4Beijing Key Lab of Hearing Impairment for Prevention and Treatment

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Please note that some of the translations on this page are AI generated. Click here for the English version.

微型猪(迷你猪)是研究人工耳蜗的理想大型动物模型。小型猪的人工耳蜗植入手术可用于提供新型电极阵列和手术方法在类似于人类的生命系统中的安全性和潜在性能的初步证据。

小型猪舍的人工耳蜗植入手术可用于提供新型电极区域的安全性和潜在性能的有意证据,以及在类似于人类的生命系统中的手术方法。迷你猪是用于研究人工耳蜗植入物的内窥实验室动物模型。小型耳荚蜗上的人工耳蜗为患有严重至重度感觉神经听力损失的移植患者提供了一个单独的平台。

此外,它还为大型动物模型中的听力损失提供了基因治疗的手术损失。因为它们在形态和结构上具有重要意义和相似性,介于迷你猪和人类之间的嗅觉器官上。这种手术方法阐明了程序,对初学者很有帮助。

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