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Circuiti digitali genici basati su sistemi CRISPR-Cas e proteine anti-CRISPR

Article DOI: 10.3791/64539-v • 10:46 min • October 18th, 2022
October 18th, 2022 •
*1, *1, 1
1School of Pharmaceutical Science and Technology, Tianjin University
* These authors contributed equally

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I sistemi CRISPR-Cas e le proteine anti-CRISPR sono stati integrati nello schema delle porte booleane in Saccharomyces cerevisiae. I nuovi piccoli circuiti logici hanno mostrato buone prestazioni e approfondito la comprensione sia dei fattori di trascrizione basati su dCas9/dCas12a che delle proprietà delle proteine anti-CRISPR.

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Retraction CRISPR-Cas system dSpCas9 denAsCas12a dLbCas12a type II-A anti-CRISPR proteins type V-A anti-CRISPR proteins gene digital circuits Saccharomyces cerevisiae synthetic biology
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