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Medicine
在不受控制的环境中进行单腿膝伸肌运动期间基于多普勒超声的腿部血流评估
在不受控制的环境中进行单腿膝伸肌运动期间基于多普勒超声的腿部血流评估
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JoVE Journal Medicine
Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting

在不受控制的环境中进行单腿膝伸肌运动期间基于多普勒超声的腿部血流评估

Full Text
3,266 Views
09:18 min
December 15, 2023

DOI: 10.3791/65746-v

Jacob Peter Hartmann1,2,3, Rikke Krabek1, Stine B. Nymand1,3, Helene Hartmeyer1, Lasse Gliemann4, Ronan M. G. Berg1,2,3,5, Ulrik Winning Iepsen1,6

1Centre for Physical Activity Research,Copenhagen University Hospital, 2Department of Clinical Physiology and Nuclear Medicine,Copenhagen University Hospital, 3Department of Biomedical Sciences, Faculty of Health and Medical Sciences,University of Copenhagen, 4Department of Nutrition, Exercise and Sports,Integrated Physiology Group, 5Neurovascular Research Laboratory, Faculty of Life Sciences and Education,University of South Wales, 6Department of Anaesthesiology and Intensive Care,Copenhagen University Hospital, Hvidovre Hospital

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Summary

这项重测研究评估了单腿膝伸肌运动期间通过多普勒超声技术测量的腿部血流量。研究了该方法的日内、日间和评分者间信度。该方法在日内和可接受的日间可靠性方面表现出很高。然而,在休息和低工作量下,评分者之间的可靠性低得令人无法接受。

Transcript

这种方法在众多临床和研究环境中得到广泛认可和应用。本研究的主要目的是帮助提高方法的可重复性,从而为测量误差提供有价值的见解。通过这样做,我们可以说出什么是真正的生理变化,什么是由于测量误差引起的。

最终,这将增强我们对这种方法的理解。主要障碍在于探索日常生活中各种活动期间的生理变化,因为只有在特定的实验设置下才能进行此类研究。自上一次可靠性研究是在单腿膝伸肌锻炼期间进行以来,已经过去了二十多年。

在此期间,技术发生了重大变化,因此必须重新审视这一研究领域,以获得对与当前方法相关的测量时代的宝贵见解。与热稀释等其他血流测定方法相比,多普勒超声是非侵入性的,必要时可以与动脉和静脉导管插入术结合使用。它还能够进行心跳到心跳的血流速度测量,因此我们可以检测到快速变化。

未来,我们的主要目标是研究慢性阻塞性肺疾病患者骨骼肌收缩的血流调节。

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