Anthony E. Pickering Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience University of Bristol Biography Publications Institution JoVE Articles Anthony E. Pickering has not added a biography. If you are Anthony E. Pickering and would like to personalize this page please email our Author Liaison for assistance. Publications Pro-opiomelanocortin Neurons in the Nucleus of the Solitary Tract Mediate Endorphinergic Endogenous Analgesia in Mice Pain. May, 2023 | Pubmed ID: 36448978 Advancing Respiratory-cardiovascular Physiology with the Working Heart-brainstem Preparation over 25 Years The Journal of Physiology. May, 2022 | Pubmed ID: 35294064 Simultaneous Brain, Brainstem, and Spinal Cord Pharmacological-fMRI Reveals Involvement of an Endogenous Opioid Network in Attentional Analgesia ELife. Jan, 2022 | Pubmed ID: 35080494 Evaluating the Association of TRPA1 Gene Polymorphisms with Pain Sensitivity: a Protocol for an Adaptive Recall by Genotype Study BMC Medical Genomics. Jan, 2022 | Pubmed ID: 35022050 Multisite Silicon Probes Enable Simultaneous Recording of Spontaneous and Evoked Activity in Multiple Isolated C-fibres in Rat Saphenous Nerve Journal of Neuroscience Methods. Feb, 2022 | Pubmed ID: 34800543 Identification of the Source Events for Aerosol Generation During Oesophago-gastro-duodenoscopy Gut. May, 2022 | Pubmed ID: 34187844 Central Pain Modulatory Mechanisms of Attentional Analgesia Are Preserved in Fibromyalgia Pain. Jan, 2022 | Pubmed ID: 33941755 Loss of Cortical Control over the Descending Pain Modulatory System Determines the Development of the Neuropathic Pain State in Rats ELife. Feb, 2021 | Pubmed ID: 33555256 The Safety of Anaesthetists and Intensivists During the First COVID-19 Surge Supports Extension of Use of Airborne Protection PPE to Ward Staff Clinical Medicine (London, England). Mar, 2021 | Pubmed ID: 33509933 The Effects of Xenon on Sevoflurane Anesthesia-induced Acidosis and Brain Cell Apoptosis in Immature Rats Paediatric Anaesthesia. Mar, 2021 | Pubmed ID: 33187024 Parallel Cortical-brainstem Pathways to Attentional Analgesia NeuroImage. Feb, 2021 | Pubmed ID: 33186712 Anatomically and Functionally Distinct Locus Coeruleus Efferents Mediate Opposing Effects on Anxiety-like Behavior Neurobiology of Stress. Nov, 2020 | Pubmed ID: 33344735 Sweet Taste Does Not Modulate Pain Perception in Adult Humans Wellcome Open Research. 2020 | Pubmed ID: 32704547 Noradrenaline Release from Locus Coeruleus Terminals in the Hippocampus Enhances Excitation-Spike Coupling in CA1 Pyramidal Neurons Via β-Adrenoceptors Cerebral Cortex (New York, N.Y. : 1991). Nov, 2020 | Pubmed ID: 32607551 Probabilistic, Spinally-gated Control of Bladder Pressure and Autonomous Micturition by Barrington's Nucleus CRH Neurons ELife. Apr, 2020 | Pubmed ID: 32347794 Locus Coeruleus Norepinephrine Activity Mediates Sensory-evoked Awakenings from Sleep Science Advances. Apr, 2020 | Pubmed ID: 32285002 Interventions to Treat Pain in Paediatric CFS/ME: a Systematic Review BMJ Paediatrics Open. 2020 | Pubmed ID: 32201745 Regulation of Food Intake by Astrocytes in the Brainstem Dorsal Vagal Complex Glia. Jun, 2020 | Pubmed ID: 31880353 Evaluation of a Primary Care-based Opioid and Pain Review Service: a Mixed-methods Evaluation in Two GP Practices in England The British Journal of General Practice : the Journal of the Royal College of General Practitioners. Feb, 2020 | Pubmed ID: 31791939 Acceptability of a Primary Care-based Opioid and Pain Review Service: a Mixed-methods Evaluation in England The British Journal of General Practice : the Journal of the Royal College of General Practitioners. Feb, 2020 | Pubmed ID: 31594772 Redefining Noradrenergic Neuromodulation of Behavior: Impacts of a Modular Locus Coeruleus Architecture The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2019 | Pubmed ID: 31619493 On the Presence and Functional Significance of Sympathetic Premotor Neurons with Collateralized Spinal Axons in the Rat The Journal of Physiology. Jul, 2019 | Pubmed ID: 31077360 Hedonic Drinking Engages a Supraspinal Inhibition of Thermal Nociception in Adult Rats Pain. May, 2019 | Pubmed ID: 31008815 Influence of Sildenafil on the Purinergic Components of Nerve-mediated and Urothelial ATP Release from the Bladder of Normal and Spinal Cord Injured Mice British Journal of Pharmacology. Jul, 2019 | Pubmed ID: 30924527 Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities Anesthesia and Analgesia. Apr, 2019 | Pubmed ID: 30883414 Behavioral Correlates of Activity of Optogenetically Identified Locus Coeruleus Noradrenergic Neurons in Rats Performing T-maze Tasks Scientific Reports. Feb, 2019 | Pubmed ID: 30718532 Platelet Dysfunction After Out of Hospital Cardiac Arrest. Results from POHCAR: A Prospective Observational, Cohort Study Resuscitation. Mar, 2019 | Pubmed ID: 30716426 Sildenafil, a Phosphodiesterase Type 5 Inhibitor, Augments Sphincter Bursting and Bladder Afferent Activity to Enhance Storage Function and Voiding Efficiency in Mice BJU International. Jul, 2019 | Pubmed ID: 30636087 Locus Coeruleus Tracking of Prediction Errors Optimises Cognitive Flexibility: An Active Inference Model PLoS Computational Biology. Jan, 2019 | Pubmed ID: 30608922 Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder Frontiers in Physiology. 2018 | Pubmed ID: 30687132 Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory Current Biology : CB. Nov, 2018 | Pubmed ID: 30393040 Ultrasound-guided, Open-source Microneurography: Approaches to Improve Recordings from Peripheral Nerves in Man Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Nov, 2018 | Pubmed ID: 30107982 Characterization of Mouse Neuro-urological Dynamics in a Novel Decerebrate Arterially Perfused Mouse (DAPM) Preparation Neurourology and Urodynamics. Apr, 2018 | Pubmed ID: 29333621 Functional Dichotomy in Spinal- Vs Prefrontal-projecting Locus Coeruleus Modules Splits Descending Noradrenergic Analgesia from Ascending Aversion and Anxiety in Rats ELife. Oct, 2017 | Pubmed ID: 29027903 Muro-Neuro-Urodynamics; a Review of the Functional Assessment of Mouse Lower Urinary Tract Function Frontiers in Physiology. 2017 | Pubmed ID: 28220079 Single Electrode Deep Brain Stimulation with Dual Targeting at Dual Frequency for the Treatment of Chronic Pain: A Case Series and Review of the Literature Brain Sciences. Jan, 2017 | Pubmed ID: 28098766 Resolving the Brainstem Contributions to Attentional Analgesia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2017 | Pubmed ID: 28096471 Deep Brain Stimulation of the Periaqueductal Gray Releases Endogenous Opioids in Humans NeuroImage. Feb, 2017 | Pubmed ID: 27554530 Brainstem Sources of Cardiac Vagal Tone and Respiratory Sinus Arrhythmia The Journal of Physiology. Dec, 2016 | Pubmed ID: 27654879 Characterising the Analgesic Effect of Different Targets for Deep Brain Stimulation in Trigeminal Anaesthesia Dolorosa Stereotactic and Functional Neurosurgery. 2016 | Pubmed ID: 27322524 Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea PloS One. 2016 | Pubmed ID: 27077912 Retrograde Optogenetic Characterization of the Pontospinal Module of the Locus Coeruleus with a Canine Adenoviral Vector Brain Research. Jun, 2016 | Pubmed ID: 26903420 Influence of Age on Respiratory Modulation of Muscle Sympathetic Nerve Activity, Blood Pressure and Baroreflex Function in Humans Experimental Physiology. Sep, 2015 | Pubmed ID: 26154775 Modelling the Vascular Response to Sympathetic Postganglionic Nerve Activity Journal of Theoretical Biology. Apr, 2015 | Pubmed ID: 25698230 Intrathecal Reboxetine Suppresses Evoked and Ongoing Neuropathic Pain Behaviours by Restoring Spinal Noradrenergic Inhibitory Tone Pain. Feb, 2015 | Pubmed ID: 25599454 Increased Intrinsic Excitability of Muscle Vasoconstrictor Preganglionic Neurons May Contribute to the Elevated Sympathetic Activity in Hypertensive Rats Journal of Neurophysiology. Dec, 2014 | Pubmed ID: 25122704 Mapping the Cellular Electrophysiology of Rat Sympathetic Preganglionic Neurones to Their Roles in Cardiorespiratory Reflex Integration: a Whole Cell Recording Study in Situ The Journal of Physiology. May, 2014 | Pubmed ID: 24665100 Optoactivation of Locus Ceruleus Neurons Evokes Bidirectional Changes in Thermal Nociception in Rats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2014 | Pubmed ID: 24647936 Systemic Dexmedetomidine Augments Inhibitory Synaptic Transmission in the Superficial Dorsal Horn Through Activation of Descending Noradrenergic Control: an in Vivo Patch-clamp Analysis of Analgesic Mechanisms Pain. Mar, 2014 | Pubmed ID: 24355412 Prolonged Ketamine Infusion As a Therapy for Complex Regional Pain Syndrome: Synergism with Antagonism? British Journal of Clinical Pharmacology. Feb, 2014 | Pubmed ID: 23701138 A Functional Analysis of the Influence of β3-adrenoceptors on the Rat Micturition Cycle The Journal of Pharmacology and Experimental Therapeutics. Nov, 2013 | Pubmed ID: 24008334 Processing of Central and Reflex Vagal Drives by Rat Cardiac Ganglion Neurones: an Intracellular Analysis The Journal of Physiology. Dec, 2011 | Pubmed ID: 22005679 An Exploration of the Control of Micturition Using a Novel in Situ Arterially Perfused Rat Preparation Frontiers in Neuroscience. 2011 | Pubmed ID: 21625609 TRPA1-expressing Primary Afferents Synapse with a Morphologically Identified Subclass of Substantia Gelatinosa Neurons in the Adult Rat Spinal Cord The European Journal of Neuroscience. Jun, 2010 | Pubmed ID: 20497466 Analgesia in Conjunction with Normalisation of Thermal Sensation Following Deep Brain Stimulation for Central Post-stroke Pain Pain. Dec, 2009 | Pubmed ID: 19833434 Retrograde Viral Vector-mediated Inhibition of Pontospinal Noradrenergic Neurons Causes Hyperalgesia in Rats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19828800 Retrograde Adenoviral Vector Targeting of Nociresponsive Pontospinal Noradrenergic Neurons in the Rat in Vivo The Journal of Comparative Neurology. Jan, 2009 | Pubmed ID: 19003793 Dominant Role of Aortic Baroreceptors in the Cardiac Baroreflex of the Rat in Situ Autonomic Neuroscience : Basic & Clinical. Nov, 2008 | Pubmed ID: 18479978 Hierarchical Recruitment of the Sympathetic and Parasympathetic Limbs of the Baroreflex in Normotensive and Spontaneously Hypertensive Rats The Journal of Physiology. Mar, 2007 | Pubmed ID: 17170043 Reflexly Evoked Coactivation of Cardiac Vagal and Sympathetic Motor Outflows: Observations and Functional Implications Clinical and Experimental Pharmacology & Physiology. Dec, 2006 | Pubmed ID: 17184509 Disinhibition of the Cardiac Limb of the Arterial Baroreflex in Rat: a Role for Metabotropic Glutamate Receptors in the Nucleus Tractus Solitarii The Journal of Physiology. Sep, 2006 | Pubmed ID: 16809369 A Decerebrate, Artificially-perfused in Situ Preparation of Rat: Utility for the Study of Autonomic and Nociceptive Processing Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16499970 Targeting Brain Stem Centers of Cardiovascular Control Using Adenoviral Vectors: Impact of Promoters on Transgene Expression Physiological Genomics. Jan, 2005 | Pubmed ID: 15561757 Nociception Attenuates Parasympathetic but Not Sympathetic Baroreflex Via NK1 Receptors in the Rat Nucleus Tractus Solitarii The Journal of Physiology. Sep, 2003 | Pubmed ID: 12813142 Investigation of Systemic Bupivacaine Toxicity Using the in Situ Perfused Working Heart-brainstem Preparation of the Rat Anesthesiology. Dec, 2002 | Pubmed ID: 12459684 The Nucleus of the Solitary Tract: an Integrating Station for Nociceptive and Cardiorespiratory Afferents Experimental Physiology. Mar, 2002 | Pubmed ID: 11856972 Open-Source-Echtzeit-Closed-Loop-Tracking des elektrischen Schwellenwerts für die translationale Schmerzforschung Aidan P. Nickerson1,2, Graeme W. T. Newton1, James H. O'Sullivan3, Manuel Martinez-Perez4, Anna C. Sales1, Gethin Williams5, Anthony E. Pickering1, James P. Dunham1 1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience, University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science, University of Bristol, 4Department of Aerospace Engineering, University of Bristol, 5Research Computing, University of Bristol JoVE 64898 Neurowissenschaften
Open-Source-Echtzeit-Closed-Loop-Tracking des elektrischen Schwellenwerts für die translationale Schmerzforschung Aidan P. Nickerson1,2, Graeme W. T. Newton1, James H. O'Sullivan3, Manuel Martinez-Perez4, Anna C. Sales1, Gethin Williams5, Anthony E. Pickering1, James P. Dunham1 1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience, University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science, University of Bristol, 4Department of Aerospace Engineering, University of Bristol, 5Research Computing, University of Bristol JoVE 64898 Neurowissenschaften
