Anthony E. Pickering Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience University of Bristol Biography Publications Institution JoVE Articles Anthony E. Pickering has not added a biography. If you are Anthony E. Pickering and would like to personalize this page please email our Author Liaison for assistance. Publications Pro-opiomelanocortin Neurons in the Nucleus of the Solitary Tract Mediate Endorphinergic Endogenous Analgesia in Mice Pain. May, 2023 | Pubmed ID: 36448978 Advancing Respiratory-cardiovascular Physiology with the Working Heart-brainstem Preparation over 25 Years The Journal of Physiology. May, 2022 | Pubmed ID: 35294064 Simultaneous Brain, Brainstem, and Spinal Cord Pharmacological-fMRI Reveals Involvement of an Endogenous Opioid Network in Attentional Analgesia ELife. Jan, 2022 | Pubmed ID: 35080494 Evaluating the Association of TRPA1 Gene Polymorphisms with Pain Sensitivity: a Protocol for an Adaptive Recall by Genotype Study BMC Medical Genomics. Jan, 2022 | Pubmed ID: 35022050 Multisite Silicon Probes Enable Simultaneous Recording of Spontaneous and Evoked Activity in Multiple Isolated C-fibres in Rat Saphenous Nerve Journal of Neuroscience Methods. Feb, 2022 | Pubmed ID: 34800543 Identification of the Source Events for Aerosol Generation During Oesophago-gastro-duodenoscopy Gut. May, 2022 | Pubmed ID: 34187844 Central Pain Modulatory Mechanisms of Attentional Analgesia Are Preserved in Fibromyalgia Pain. Jan, 2022 | Pubmed ID: 33941755 Loss of Cortical Control over the Descending Pain Modulatory System Determines the Development of the Neuropathic Pain State in Rats ELife. Feb, 2021 | Pubmed ID: 33555256 The Safety of Anaesthetists and Intensivists During the First COVID-19 Surge Supports Extension of Use of Airborne Protection PPE to Ward Staff Clinical Medicine (London, England). Mar, 2021 | Pubmed ID: 33509933 The Effects of Xenon on Sevoflurane Anesthesia-induced Acidosis and Brain Cell Apoptosis in Immature Rats Paediatric Anaesthesia. Mar, 2021 | Pubmed ID: 33187024 Parallel Cortical-brainstem Pathways to Attentional Analgesia NeuroImage. Feb, 2021 | Pubmed ID: 33186712 Anatomically and Functionally Distinct Locus Coeruleus Efferents Mediate Opposing Effects on Anxiety-like Behavior Neurobiology of Stress. Nov, 2020 | Pubmed ID: 33344735 Sweet Taste Does Not Modulate Pain Perception in Adult Humans Wellcome Open Research. 2020 | Pubmed ID: 32704547 Noradrenaline Release from Locus Coeruleus Terminals in the Hippocampus Enhances Excitation-Spike Coupling in CA1 Pyramidal Neurons Via β-Adrenoceptors Cerebral Cortex (New York, N.Y. : 1991). Nov, 2020 | Pubmed ID: 32607551 Probabilistic, Spinally-gated Control of Bladder Pressure and Autonomous Micturition by Barrington's Nucleus CRH Neurons ELife. Apr, 2020 | Pubmed ID: 32347794 Locus Coeruleus Norepinephrine Activity Mediates Sensory-evoked Awakenings from Sleep Science Advances. Apr, 2020 | Pubmed ID: 32285002 Interventions to Treat Pain in Paediatric CFS/ME: a Systematic Review BMJ Paediatrics Open. 2020 | Pubmed ID: 32201745 Regulation of Food Intake by Astrocytes in the Brainstem Dorsal Vagal Complex Glia. Jun, 2020 | Pubmed ID: 31880353 Evaluation of a Primary Care-based Opioid and Pain Review Service: a Mixed-methods Evaluation in Two GP Practices in England The British Journal of General Practice : the Journal of the Royal College of General Practitioners. Feb, 2020 | Pubmed ID: 31791939 Acceptability of a Primary Care-based Opioid and Pain Review Service: a Mixed-methods Evaluation in England The British Journal of General Practice : the Journal of the Royal College of General Practitioners. Feb, 2020 | Pubmed ID: 31594772 Redefining Noradrenergic Neuromodulation of Behavior: Impacts of a Modular Locus Coeruleus Architecture The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2019 | Pubmed ID: 31619493 On the Presence and Functional Significance of Sympathetic Premotor Neurons with Collateralized Spinal Axons in the Rat The Journal of Physiology. Jul, 2019 | Pubmed ID: 31077360 Hedonic Drinking Engages a Supraspinal Inhibition of Thermal Nociception in Adult Rats Pain. May, 2019 | Pubmed ID: 31008815 Influence of Sildenafil on the Purinergic Components of Nerve-mediated and Urothelial ATP Release from the Bladder of Normal and Spinal Cord Injured Mice British Journal of Pharmacology. Jul, 2019 | Pubmed ID: 30924527 Assessing Long-term Neurodevelopmental Outcome Following General Anesthesia in Early Childhood: Challenges and Opportunities Anesthesia and Analgesia. Apr, 2019 | Pubmed ID: 30883414 Behavioral Correlates of Activity of Optogenetically Identified Locus Coeruleus Noradrenergic Neurons in Rats Performing T-maze Tasks Scientific Reports. Feb, 2019 | Pubmed ID: 30718532 Platelet Dysfunction After Out of Hospital Cardiac Arrest. Results from POHCAR: A Prospective Observational, Cohort Study Resuscitation. Mar, 2019 | Pubmed ID: 30716426 Sildenafil, a Phosphodiesterase Type 5 Inhibitor, Augments Sphincter Bursting and Bladder Afferent Activity to Enhance Storage Function and Voiding Efficiency in Mice BJU International. Jul, 2019 | Pubmed ID: 30636087 Locus Coeruleus Tracking of Prediction Errors Optimises Cognitive Flexibility: An Active Inference Model PLoS Computational Biology. Jan, 2019 | Pubmed ID: 30608922 Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder Frontiers in Physiology. 2018 | Pubmed ID: 30687132 Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory Current Biology : CB. Nov, 2018 | Pubmed ID: 30393040 Ultrasound-guided, Open-source Microneurography: Approaches to Improve Recordings from Peripheral Nerves in Man Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Nov, 2018 | Pubmed ID: 30107982 Characterization of Mouse Neuro-urological Dynamics in a Novel Decerebrate Arterially Perfused Mouse (DAPM) Preparation Neurourology and Urodynamics. Apr, 2018 | Pubmed ID: 29333621 Functional Dichotomy in Spinal- Vs Prefrontal-projecting Locus Coeruleus Modules Splits Descending Noradrenergic Analgesia from Ascending Aversion and Anxiety in Rats ELife. Oct, 2017 | Pubmed ID: 29027903 Muro-Neuro-Urodynamics; a Review of the Functional Assessment of Mouse Lower Urinary Tract Function Frontiers in Physiology. 2017 | Pubmed ID: 28220079 Single Electrode Deep Brain Stimulation with Dual Targeting at Dual Frequency for the Treatment of Chronic Pain: A Case Series and Review of the Literature Brain Sciences. Jan, 2017 | Pubmed ID: 28098766 Resolving the Brainstem Contributions to Attentional Analgesia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2017 | Pubmed ID: 28096471 Deep Brain Stimulation of the Periaqueductal Gray Releases Endogenous Opioids in Humans NeuroImage. Feb, 2017 | Pubmed ID: 27554530 Brainstem Sources of Cardiac Vagal Tone and Respiratory Sinus Arrhythmia The Journal of Physiology. Dec, 2016 | Pubmed ID: 27654879 Characterising the Analgesic Effect of Different Targets for Deep Brain Stimulation in Trigeminal Anaesthesia Dolorosa Stereotactic and Functional Neurosurgery. 2016 | Pubmed ID: 27322524 Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea PloS One. 2016 | Pubmed ID: 27077912 Retrograde Optogenetic Characterization of the Pontospinal Module of the Locus Coeruleus with a Canine Adenoviral Vector Brain Research. Jun, 2016 | Pubmed ID: 26903420 Influence of Age on Respiratory Modulation of Muscle Sympathetic Nerve Activity, Blood Pressure and Baroreflex Function in Humans Experimental Physiology. Sep, 2015 | Pubmed ID: 26154775 Modelling the Vascular Response to Sympathetic Postganglionic Nerve Activity Journal of Theoretical Biology. Apr, 2015 | Pubmed ID: 25698230 Intrathecal Reboxetine Suppresses Evoked and Ongoing Neuropathic Pain Behaviours by Restoring Spinal Noradrenergic Inhibitory Tone Pain. Feb, 2015 | Pubmed ID: 25599454 Increased Intrinsic Excitability of Muscle Vasoconstrictor Preganglionic Neurons May Contribute to the Elevated Sympathetic Activity in Hypertensive Rats Journal of Neurophysiology. Dec, 2014 | Pubmed ID: 25122704 Mapping the Cellular Electrophysiology of Rat Sympathetic Preganglionic Neurones to Their Roles in Cardiorespiratory Reflex Integration: a Whole Cell Recording Study in Situ The Journal of Physiology. May, 2014 | Pubmed ID: 24665100 Optoactivation of Locus Ceruleus Neurons Evokes Bidirectional Changes in Thermal Nociception in Rats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2014 | Pubmed ID: 24647936 Systemic Dexmedetomidine Augments Inhibitory Synaptic Transmission in the Superficial Dorsal Horn Through Activation of Descending Noradrenergic Control: an in Vivo Patch-clamp Analysis of Analgesic Mechanisms Pain. Mar, 2014 | Pubmed ID: 24355412 Prolonged Ketamine Infusion As a Therapy for Complex Regional Pain Syndrome: Synergism with Antagonism? British Journal of Clinical Pharmacology. Feb, 2014 | Pubmed ID: 23701138 A Functional Analysis of the Influence of β3-adrenoceptors on the Rat Micturition Cycle The Journal of Pharmacology and Experimental Therapeutics. Nov, 2013 | Pubmed ID: 24008334 Processing of Central and Reflex Vagal Drives by Rat Cardiac Ganglion Neurones: an Intracellular Analysis The Journal of Physiology. Dec, 2011 | Pubmed ID: 22005679 An Exploration of the Control of Micturition Using a Novel in Situ Arterially Perfused Rat Preparation Frontiers in Neuroscience. 2011 | Pubmed ID: 21625609 TRPA1-expressing Primary Afferents Synapse with a Morphologically Identified Subclass of Substantia Gelatinosa Neurons in the Adult Rat Spinal Cord The European Journal of Neuroscience. Jun, 2010 | Pubmed ID: 20497466 Analgesia in Conjunction with Normalisation of Thermal Sensation Following Deep Brain Stimulation for Central Post-stroke Pain Pain. Dec, 2009 | Pubmed ID: 19833434 Retrograde Viral Vector-mediated Inhibition of Pontospinal Noradrenergic Neurons Causes Hyperalgesia in Rats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19828800 Retrograde Adenoviral Vector Targeting of Nociresponsive Pontospinal Noradrenergic Neurons in the Rat in Vivo The Journal of Comparative Neurology. Jan, 2009 | Pubmed ID: 19003793 Dominant Role of Aortic Baroreceptors in the Cardiac Baroreflex of the Rat in Situ Autonomic Neuroscience : Basic & Clinical. Nov, 2008 | Pubmed ID: 18479978 Hierarchical Recruitment of the Sympathetic and Parasympathetic Limbs of the Baroreflex in Normotensive and Spontaneously Hypertensive Rats The Journal of Physiology. Mar, 2007 | Pubmed ID: 17170043 Reflexly Evoked Coactivation of Cardiac Vagal and Sympathetic Motor Outflows: Observations and Functional Implications Clinical and Experimental Pharmacology & Physiology. Dec, 2006 | Pubmed ID: 17184509 Disinhibition of the Cardiac Limb of the Arterial Baroreflex in Rat: a Role for Metabotropic Glutamate Receptors in the Nucleus Tractus Solitarii The Journal of Physiology. Sep, 2006 | Pubmed ID: 16809369 A Decerebrate, Artificially-perfused in Situ Preparation of Rat: Utility for the Study of Autonomic and Nociceptive Processing Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16499970 Targeting Brain Stem Centers of Cardiovascular Control Using Adenoviral Vectors: Impact of Promoters on Transgene Expression Physiological Genomics. Jan, 2005 | Pubmed ID: 15561757 Nociception Attenuates Parasympathetic but Not Sympathetic Baroreflex Via NK1 Receptors in the Rat Nucleus Tractus Solitarii The Journal of Physiology. Sep, 2003 | Pubmed ID: 12813142 Investigation of Systemic Bupivacaine Toxicity Using the in Situ Perfused Working Heart-brainstem Preparation of the Rat Anesthesiology. Dec, 2002 | Pubmed ID: 12459684 The Nucleus of the Solitary Tract: an Integrating Station for Nociceptive and Cardiorespiratory Afferents Experimental Physiology. Mar, 2002 | Pubmed ID: 11856972 중개 통증 연구를 위한 오픈 소스 실시간 폐쇄 루프 전기 임계값 추적 Aidan P. Nickerson1,2, Graeme W. T. Newton1, James H. O'Sullivan3, Manuel Martinez-Perez4, Anna C. Sales1, Gethin Williams5, Anthony E. Pickering1, James P. Dunham1 1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience, University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science, University of Bristol, 4Department of Aerospace Engineering, University of Bristol, 5Research Computing, University of Bristol JoVE 64898 Neurowissenschaften
중개 통증 연구를 위한 오픈 소스 실시간 폐쇄 루프 전기 임계값 추적 Aidan P. Nickerson1,2, Graeme W. T. Newton1, James H. O'Sullivan3, Manuel Martinez-Perez4, Anna C. Sales1, Gethin Williams5, Anthony E. Pickering1, James P. Dunham1 1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience, University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science, University of Bristol, 4Department of Aerospace Engineering, University of Bristol, 5Research Computing, University of Bristol JoVE 64898 Neurowissenschaften
