David Van Vactor Blavatnik Institute of Cell Biology and Program in Neuroscience Harvard Medical School Biography Publications Institution JoVE Articles David Van Vactor has not added a biography. If you are David Van Vactor and would like to personalize this page please email our Author Liaison for assistance. Publications Drosophila Enabled Promotes Synapse Morphogenesis and Regulates Active Zone Form and Function Neural Development. Mar, 2020 | Pubmed ID: 32183907 The Conserved MicroRNA MiR-34 Regulates Synaptogenesis Via Coordination of Distinct Mechanisms in Presynaptic and Postsynaptic Cells Nature Communications. 02, 2020 | Pubmed ID: 32107390 DTACC Restricts Bouton Addition and Regulates Microtubule Organization at the Drosophila Neuromuscular Junction Cytoskeleton (Hoboken, N.J.). Jan, 2020 | Pubmed ID: 31702858 MicroRNAs Regulate Multiple Aspects of Locomotor Behavior in G3 (Bethesda, Md.). 01, 2020 | Pubmed ID: 31694853 MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila Cell Reports. 06, 2018 | Pubmed ID: 29949763 Regulation of Circadian Behavior by Astroglial MicroRNAs in Genetics. 03, 2018 | Pubmed ID: 29487148 Presynaptic Morphogenesis, Active Zone Organization and Structural Plasticity in Drosophila Current Opinion in Neurobiology. 04, 2017 | Pubmed ID: 28388491 The Drosophila Tricellular Junction Protein Gliotactin Regulates Its Own MRNA Levels Through BMP-mediated Induction of MiR-184 Journal of Cell Science. Apr, 2016 | Pubmed ID: 26906422 MicroRNAs That Promote or Inhibit Memory Formation in Drosophila Melanogaster Genetics. Jun, 2015 | Pubmed ID: 26088433 A Transgenic Resource for Conditional Competitive Inhibition of Conserved Drosophila MicroRNAs Nature Communications. Jun, 2015 | Pubmed ID: 26081261 QIL1 is a Novel Mitochondrial Protein Required for MICOS Complex Stability and Cristae Morphology ELife. May, 2015 | Pubmed ID: 25997101 MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells PLoS Genetics. May, 2015 | Pubmed ID: 25993106 Dysregulation of MicroRNA-219 Promotes Neurodegeneration Through Post-transcriptional Regulation of Tau The Journal of Clinical Investigation. Feb, 2015 | Pubmed ID: 25574843 MicroRNA-8 Promotes Robust Motor Axon Targeting by Coordinate Regulation of Cell Adhesion Molecules During Synapse Development Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Sep, 2014 | Pubmed ID: 25135978 MiR-8 Controls Synapse Structure by Repression of the Actin Regulator Enabled Development (Cambridge, England). May, 2014 | Pubmed ID: 24718988 Quality Assessment and Control of Tissue Specific RNA-seq Libraries of Drosophila Transgenic RNAi Models Frontiers in Genetics. 2014 | Pubmed ID: 24634674 BDNF Promotes Axon Branching of Retinal Ganglion Cells Via MiRNA-132 and P250GAP The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2014 | Pubmed ID: 24431455 Growth Cone-specific Functions of XMAP215 in Restricting Microtubule Dynamics and Promoting Axonal Outgrowth Neural Development. 2013 | Pubmed ID: 24289819 Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland CAMP/PKA Signaling Defects in the Drosophila Melanogaster Neurofibromatosis-1 Growth Deficiency PLoS Genetics. Nov, 2013 | Pubmed ID: 24278035 Drosophila Growth Cones Advance by Forward Translocation of the Neuronal Cytoskeletal Meshwork in Vivo PloS One. 2013 | Pubmed ID: 24244629 Retrograde BMP Signaling at the Synapse: a Permissive Signal for Synapse Maturation and Activity-dependent Plasticity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2013 | Pubmed ID: 24198381 Embryonic and Larval Neural Connectivity: Progressive Changes in Synapse Form and Function at the Neuromuscular Junction Mediated by Cytoskeletal Regulation Wiley Interdisciplinary Reviews. Developmental Biology. Nov-Dec, 2013 | Pubmed ID: 24123935 Genetic Circuitry of Survival Motor Neuron, the Gene Underlying Spinal Muscular Atrophy Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23757500 Catalyzing Curriculum Evolution in Graduate Science Education Cell. May, 2013 | Pubmed ID: 23663771 Drosophila Semaphorin2b is Required for the Axon Guidance of a Subset of Embryonic Neurons Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2013 | Pubmed ID: 23606306 MicroRNA-276a Functions in Ellipsoid Body and Mushroom Body Neurons for Naive and Conditioned Olfactory Avoidance in Drosophila The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2013 | Pubmed ID: 23536094 Multiparametric Analysis of CLASP-interacting Protein Functions During Interphase Microtubule Dynamics Molecular and Cellular Biology. Apr, 2013 | Pubmed ID: 23382075 MicroRNAs Shape the Neuronal Landscape Neuron. Aug, 2012 | Pubmed ID: 22884321 MiR-132 Enhances Dendritic Morphogenesis, Spine Density, Synaptic Integration, and Survival of Newborn Olfactory Bulb Neurons PloS One. 2012 | Pubmed ID: 22693596 Maintaining Muscle Mitochondria Via Transsynaptic Signaling Developmental Cell. Feb, 2012 | Pubmed ID: 22340490 Heparan Sulfate Proteoglycan Specificity During Axon Pathway Formation in the Drosophila Embryo Developmental Neurobiology. Jul, 2011 | Pubmed ID: 21500363 Conserved Genes Act As Modifiers of Invertebrate SMN Loss of Function Defects PLoS Genetics. Oct, 2010 | Pubmed ID: 21124729 Understanding Neuronal Connectivity Through the Post-transcriptional Toolkit Genes & Development. Apr, 2010 | Pubmed ID: 20360381 Transgenic MicroRNA Inhibition with Spatiotemporal Specificity in Intact Organisms Nature Methods. Dec, 2009 | Pubmed ID: 19915559 Complex Interactions Amongst N-cadherin, DLAR, and Liprin-alpha Regulate Drosophila Photoreceptor Axon Targeting Developmental Biology. Dec, 2009 | Pubmed ID: 19766621 The Trip of the Tip: Understanding the Growth Cone Machinery Nature Reviews. Molecular Cell Biology. May, 2009 | Pubmed ID: 19373241 Fak56 Functions Downstream of Integrin AlphaPS3betanu and Suppresses MAPK Activation in Neuromuscular Junction Growth Neural Development. Oct, 2008 | Pubmed ID: 18925939 Modeling Spinal Muscular Atrophy in Drosophila PloS One. Sep, 2008 | Pubmed ID: 18791638 Synapses and Growth Cones on Two Sides of a Highwire Neuron. Feb, 2008 | Pubmed ID: 18255027 Synapse Specificity: Wnts Keep Motor Axons on Target Current Biology : CB. Oct, 2007 | Pubmed ID: 17956753 The HSPGs Syndecan and Dallylike Bind the Receptor Phosphatase LAR and Exert Distinct Effects on Synaptic Development Neuron. Feb, 2006 | Pubmed ID: 16476662 Heparan Sulfate Proteoglycans and the Emergence of Neuronal Connectivity Current Opinion in Neurobiology. Feb, 2006 | Pubmed ID: 16417999 Direct Observation Demonstrates That Liprin-alpha is Required for Trafficking of Synaptic Vesicles Current Biology : CB. Apr, 2005 | Pubmed ID: 15823543 The Microtubule Plus End Tracking Protein Orbit/MAST/CLASP Acts Downstream of the Tyrosine Kinase Abl in Mediating Axon Guidance Neuron. Jun, 2004 | Pubmed ID: 15207236 Axonal Heparan Sulfate Proteoglycans Regulate the Distribution and Efficiency of the Repellent Slit During Midline Axon Guidance Current Biology : CB. Mar, 2004 | Pubmed ID: 15043815 Functions of the Ectodomain and Cytoplasmic Tyrosine Phosphatase Domains of Receptor Protein Tyrosine Phosphatase Dlar in Vivo Molecular and Cellular Biology. Oct, 2003 | Pubmed ID: 12972609 Neurons Take Shape Current Biology : CB. Feb, 2003 | Pubmed ID: 12593820 Receptor Protein Tyrosine Phosphatases in Nervous System Development Physiological Reviews. Jan, 2003 | Pubmed ID: 12506125 A Drosophila Homolog of Cyclase-associated Proteins Collaborates with the Abl Tyrosine Kinase to Control Midline Axon Pathfinding Neuron. Nov, 2002 | Pubmed ID: 12441051 GAPs in Slit-Robo Signaling BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. May, 2002 | Pubmed ID: 12001262 Drosophila Liprin-alpha and the Receptor Phosphatase Dlar Control Synapse Morphogenesis Neuron. Mar, 2002 | Pubmed ID: 11931739 Axon Guidance: the Cytoplasmic Tail Current Opinion in Cell Biology. Apr, 2002 | Pubmed ID: 11891122 Adhesion and Signaling in Axonal Fasciculation Current Opinion in Neurobiology. Feb, 1998 | Pubmed ID: 9568395 3D Particle Tracking for Noninvasive In Vivo Analysis of Synaptic Microtubule Dynamics in Dendrites and Neuromuscular Junctions of Drosophila Vivian T. Chou*1, Hunkar Gizem Yesilyurt*1, Hoyin Lai*2, Jennifer B. Long1, Mercedes Arnes1, Kamal Obbad1, Michael Jones2, Hideki Sasaki2, Luciano A.G. Lucas2, Sam Alworth2, James Shih-Jong Lee2, David Van Vactor1 1Blavatnik Institute of Cell Biology and Program in Neuroscience, Harvard Medical School, 2DRVision Technologies LLC JoVE 61159 Neurowissenschaften Neural Explant Cultures from Xenopus laevis Laura Anne Lowery1, Anna E.R. Faris1, Alina Stout1, David Van Vactor1 1Department of Cell Biology, Harvard Medical School JoVE 4232 Neurowissenschaften
3D Particle Tracking for Noninvasive In Vivo Analysis of Synaptic Microtubule Dynamics in Dendrites and Neuromuscular Junctions of Drosophila Vivian T. Chou*1, Hunkar Gizem Yesilyurt*1, Hoyin Lai*2, Jennifer B. Long1, Mercedes Arnes1, Kamal Obbad1, Michael Jones2, Hideki Sasaki2, Luciano A.G. Lucas2, Sam Alworth2, James Shih-Jong Lee2, David Van Vactor1 1Blavatnik Institute of Cell Biology and Program in Neuroscience, Harvard Medical School, 2DRVision Technologies LLC JoVE 61159 Neurowissenschaften
Neural Explant Cultures from Xenopus laevis Laura Anne Lowery1, Anna E.R. Faris1, Alina Stout1, David Van Vactor1 1Department of Cell Biology, Harvard Medical School JoVE 4232 Neurowissenschaften
