Eng H. Lo Neuroprotection Research Laboratory, Departments of Radiology and Neurology Massachusetts General Hospital and Harvard Medical School Biography Publications Institution JoVE Articles Eng H. Lo has not added a biography. If you are Eng H. Lo and would like to personalize this page please email our Author Liaison for assistance. Publications Pro-angiogenic Effects of Resveratrol in Brain Endothelial Cells: Nitric Oxide-mediated Regulation of Vascular Endothelial Growth Factor and Metalloproteinases Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2012 | Pubmed ID: 22314268 Plasma Biomarker May Help to Distinguish Acute CVST from Non-thrombotic CVSS in Emergency International Journal of Stroke : Official Journal of the International Stroke Society. Feb, 2012 | Pubmed ID: 22264373 Plasmalemma Permeability and Necrotic Cell Death Phenotypes After Intracerebral Hemorrhage in Mice Stroke; a Journal of Cerebral Circulation. Feb, 2012 | Pubmed ID: 22076006 A Rat Model of Studying Tissue-type Plasminogen Activator Thrombolysis in Ischemic Stroke with Diabetes Stroke; a Journal of Cerebral Circulation. Feb, 2012 | Pubmed ID: 22052516 Recombinant Activated Coagulation Factor VII and Prothrombin Complex Concentrates Are Equally Effective in Reducing Hematoma Volume in Experimental Warfarin-associated Intracerebral Hemorrhage Stroke; a Journal of Cerebral Circulation. Jan, 2012 | Pubmed ID: 21998055 Combination Therapy Targeting Akt and Mammalian Target of Rapamycin Improves Functional Outcome After Controlled Cortical Impact in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2012 | Pubmed ID: 21934697 Fast Radio-frequency Enforced Steady State (FRESS) Spin Echo MRI for Quantitative T(2) Mapping: Minimizing the Apparent Repetition Time (TR) Dependence for Fast T(2) Measurement NMR in Biomedicine. Feb, 2012 | Pubmed ID: 21755552 Traumatic Brain Injury During Warfarin Anticoagulation - An Experimental Study in Mice Journal of Neurotrauma. Dec, 2011 | Pubmed ID: 22142342 Kollidon VA64, a Membrane-resealing Agent, Reduces Histopathology and Improves Functional Outcome After Controlled Cortical Impact in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Nov, 2011 | Pubmed ID: 22086196 Cortical Excitation and Inhibition Following Focal Traumatic Brain Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 21976493 Neuroglobin is an Endogenous Neuroprotectant for Retinal Ganglion Cells Against Glaucomatous Damage The American Journal of Pathology. Dec, 2011 | Pubmed ID: 21967817 Plasma-type Gelsolin is Decreased in Human Blood and Cerebrospinal Fluid After Subarachnoid Hemorrhage Stroke; a Journal of Cerebral Circulation. Dec, 2011 | Pubmed ID: 21940962 Anticoagulation with the Oral Direct Thrombin Inhibitor Dabigatran Does Not Enlarge Hematoma Volume in Experimental Intracerebral Hemorrhage Circulation. Oct, 2011 | Pubmed ID: 21911784 Vascular Endothelial Growth Factor Regulates the Migration of Oligodendrocyte Precursor Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2011 | Pubmed ID: 21775609 Cerebral Edema and a Transtentorial Brain Herniation Syndrome Associated with Pandemic Swine Influenza A (H1N1) Virus Infection Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Sep, 2011 | Pubmed ID: 21742505 Intracranial Hemorrhage: Mechanisms of Secondary Brain Injury Acta Neurochirurgica. Supplement. 2011 | Pubmed ID: 21725733 Cellular Mechanisms of Neurovascular Damage and Repair After Stroke Journal of Child Neurology. Sep, 2011 | Pubmed ID: 21628695 Decreased Cerebrovascular Brain-derived Neurotrophic Factor-mediated Neuroprotection in the Diabetic Brain Diabetes. Jun, 2011 | Pubmed ID: 21562076 Stroke-related Translational Research Archives of Neurology. Sep, 2011 | Pubmed ID: 21555605 γ-glutamylcysteine Ethyl Ester Protects Cerebral Endothelial Cells During Injury and Decreases Blood-brain Barrier Permeability After Experimental Brain Trauma Journal of Neurochemistry. Jul, 2011 | Pubmed ID: 21534958 Effect of Normobaric Oxygen Therapy in a Rat Model of Intracerebral Hemorrhage Stroke; a Journal of Cerebral Circulation. May, 2011 | Pubmed ID: 21415401 Antiplatelet Pretreatment Does Not Increase Hematoma Volume in Experimental Intracerebral Hemorrhage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2011 | Pubmed ID: 21386857 Association Between PH-weighted Endogenous Amide Proton Chemical Exchange Saturation Transfer MRI and Tissue Lactic Acidosis During Acute Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2011 | Pubmed ID: 21386856 Fingolimod Provides Long-term Protection in Rodent Models of Cerebral Ischemia Annals of Neurology. Jan, 2011 | Pubmed ID: 21280082 Proteomic Temporal Profile of Human Brain Endothelium After Oxidative Stress Stroke; a Journal of Cerebral Circulation. Jan, 2011 | Pubmed ID: 21164131 Tumor Necrosis Factor Alpha and Fas Receptor Contribute to Cognitive Deficits Independent of Cell Death After Concussive Traumatic Brain Injury in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2011 | Pubmed ID: 20940727 Proteomic Protease Substrate Profiling of TPA Treatment in Acute Ischemic Stroke Patients: A Step Toward Individualizing Thrombolytic Therapy at the Bedside Translational Stroke Research. Dec, 2010 | Pubmed ID: 22140417 Opportunities and Challenges in Omics Translational Stroke Research. Dec, 2010 | Pubmed ID: 22140416 Fingolimod Provides Long-term Protection in Rodent Models of Cerebral Ischemia Annals of Neurology. Nov, 2010 | Pubmed ID: 21077181 Degeneration and Repair in Central Nervous System Disease Nature Medicine. Nov, 2010 | Pubmed ID: 21052074 Biphasic Actions of HMGB1 Signaling in Inflammation and Recovery After Stroke Annals of the New York Academy of Sciences. Oct, 2010 | Pubmed ID: 20955426 Annexin A2: a Tissue Plasminogen Activator Amplifier for Thrombolytic Stroke Therapy Stroke; a Journal of Cerebral Circulation. Oct, 2010 | Pubmed ID: 20876506 Two-photon High-resolution Measurement of Partial Pressure of Oxygen in Cerebral Vasculature and Tissue Nature Methods. Sep, 2010 | Pubmed ID: 20693997 High-mobility Group Box 1 Promotes Metalloproteinase-9 Upregulation Through Toll-like Receptor 4 After Cerebral Ischemia Stroke; a Journal of Cerebral Circulation. Sep, 2010 | Pubmed ID: 20671243 The Science of Stroke: Mechanisms in Search of Treatments Neuron. Jul, 2010 | Pubmed ID: 20670828 Amelioration of Inflammation and Cytotoxicity by Dipyridamole in Brain Endothelial Cells Cerebrovascular Diseases (Basel, Switzerland). Aug, 2010 | Pubmed ID: 20664263 Stroke: Working Toward a Prioritized World Agenda International Journal of Stroke : Official Journal of the International Stroke Society. Aug, 2010 | Pubmed ID: 20636706 Stroke: Working Toward a Prioritized World Agenda Cerebrovascular Diseases (Basel, Switzerland). 2010 | Pubmed ID: 20516682 Stroke: Working Toward a Prioritized World Agenda Stroke; a Journal of Cerebral Circulation. Jun, 2010 | Pubmed ID: 20498453 Induction of Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 Via CD47 Signaling in Neurovascular Cells Neurochemical Research. Jul, 2010 | Pubmed ID: 20364320 Role of ERK Map Kinase and CRM1 in IL-1beta-stimulated Release of HMGB1 from Cortical Astrocytes Glia. Jun, 2010 | Pubmed ID: 20222144 Genetic Analysis of the Role of Tumor Necrosis Factor Receptors in Functional Outcome After Traumatic Brain Injury in Mice Journal of Neurotrauma. Jun, 2010 | Pubmed ID: 20205514 Annexin A2 Combined with Low-dose TPA Improves Thrombolytic Therapy in a Rat Model of Focal Embolic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2010 | Pubmed ID: 20068577 Increased Nuclear Apoptosis-inducing Factor After Transient Focal Ischemia: a 12/15-lipoxygenase-dependent Organelle Damage Pathway Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2010 | Pubmed ID: 20068575 Inhibition of Reactive Astrocytes with Fluorocitrate Retards Neurovascular Remodeling and Recovery After Focal Cerebral Ischemia in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2010 | Pubmed ID: 19997116 Edaravone, a Free Radical Scavenger, Protects Components of the Neurovascular Unit Against Oxidative Stress in Vitro Brain Research. Jan, 2010 | Pubmed ID: 19840779 Astrocytes Protect Oligodendrocyte Precursor Cells Via MEK/ERK and PI3K/Akt Signaling Journal of Neuroscience Research. Mar, 2010 | Pubmed ID: 19830833 Experimental Models for Analysis of Oligodendrocyte Pathophysiology in Stroke Experimental & Translational Stroke Medicine. 2009 | Pubmed ID: 20150984 Oligovascular Signaling in White Matter Stroke Biological & Pharmaceutical Bulletin. Oct, 2009 | Pubmed ID: 19801821 12/15-Lipoxygenase Targets Neuronal Mitochondria Under Oxidative Stress Journal of Neurochemistry. Nov, 2009 | Pubmed ID: 19737346 Brain Angiogenesis in Developmental and Pathological Processes: Neurovascular Injury and Angiogenic Recovery After Stroke The FEBS Journal. Sep, 2009 | Pubmed ID: 19664070 T Time in the Brain Nature Medicine. Aug, 2009 | Pubmed ID: 19661986 Combination Therapy with Normobaric Oxygen (NBO) Plus Thrombolysis in Experimental Ischemic Stroke BMC Neuroscience. 2009 | Pubmed ID: 19604385 Plasma and Brain Matrix Metalloproteinase-9 After Acute Focal Cerebral Ischemia in Rats Stroke; a Journal of Cerebral Circulation. Aug, 2009 | Pubmed ID: 19556529 Matrix Metalloprotease Regulation of Neuropathic Pain Trends in Pharmacological Sciences. Jul, 2009 | Pubmed ID: 19523695 Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1 Journal of Neurotrauma. Nov, 2009 | Pubmed ID: 19469687 Mechanisms and Targets for Angiogenic Therapy After Stroke Cell Adhesion & Migration. Apr-Jun, 2009 | Pubmed ID: 19363301 Neurovascular Effects of CD47 Signaling: Promotion of Cell Death, Inflammation, and Suppression of Angiogenesis in Brain Endothelial Cells in Vitro Journal of Neuroscience Research. Aug, 2009 | Pubmed ID: 19360900 An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009 | Pubmed ID: 19357263 Rapid Reversal of Anticoagulation Reduces Hemorrhage Volume in a Mouse Model of Warfarin-associated Intracerebral Hemorrhage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2009 | Pubmed ID: 19319147 Neuroprotective Roles and Mechanisms of Neuroglobin Neurological Research. Mar, 2009 | Pubmed ID: 19298751 Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations Stroke; a Journal of Cerebral Circulation. Jun, 2009 | Pubmed ID: 19246690 Interleukin-1beta Augments Angiogenic Responses of Murine Endothelial Progenitor Cells in Vitro Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2009 | Pubmed ID: 19240740 CD47 Gene Knockout Protects Against Transient Focal Cerebral Ischemia in Mice Experimental Neurology. May, 2009 | Pubmed ID: 19233173 Doxycycline Inhibits Matrix Metalloproteinase-9 and Laminin Degradation After Transient Global Cerebral Ischemia Neurobiology of Disease. May, 2009 | Pubmed ID: 19200854 Characterization of Cerebrovascular Responses to Hyperoxia and Hypercapnia Using MRI in Rat NeuroImage. May, 2009 | Pubmed ID: 19118633 Dysfunctional Cell-cell Signaling in the Neurovascular Unit As a Paradigm for Central Nervous System Disease Stroke; a Journal of Cerebral Circulation. Mar, 2009 | Pubmed ID: 19064781 The Neurovascular Unit in Health and Disease: Introduction Stroke; a Journal of Cerebral Circulation. Mar, 2009 | Pubmed ID: 19064779 Role of Oxidative Stress and Caspase 3 in CD47-mediated Neuronal Cell Death Journal of Neurochemistry. Jan, 2009 | Pubmed ID: 19012741 Lithium Upregulates Vascular Endothelial Growth Factor in Brain Endothelial Cells and Astrocytes Stroke; a Journal of Cerebral Circulation. Feb, 2009 | Pubmed ID: 18974377 Reperfusion Injury After Stroke: Neurovascular Proteases and the Blood-brain Barrier Handbook of Clinical Neurology / Edited by P.J. Vinken and G.W. Bruyn. 2009 | Pubmed ID: 18790272 Green Tea Polyphenol (-)-epigallocatechin Gallate Reduces Neuronal Cell Damage and Up-regulation of MMP-9 Activity in Hippocampal CA1 and CA2 Areas Following Transient Global Cerebral Ischemia Journal of Neuroscience Research. Feb, 2009 | Pubmed ID: 18752302 Neuregulin-1 Signaling in Brain Endothelial Cells Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2009 | Pubmed ID: 18728681 Effects of Neuroglobin Overexpression on Mitochondrial Function and Oxidative Stress Following Hypoxia/reoxygenation in Cultured Neurons Journal of Neuroscience Research. Jan, 2009 | Pubmed ID: 18711728 Stimulus-induced Changes in Blood Flow and 2-deoxyglucose Uptake Dissociate in Ipsilateral Somatosensory Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19118167 Extension of the Thrombolytic Time Window with Minocycline in Experimental Stroke Stroke; a Journal of Cerebral Circulation. Dec, 2008 | Pubmed ID: 18927459 Experimental Model of Warfarin-associated Intracerebral Hemorrhage Stroke; a Journal of Cerebral Circulation. Dec, 2008 | Pubmed ID: 18772448 Targeting Extracellular Matrix Proteolysis for Hemorrhagic Complications of TPA Stroke Therapy CNS & Neurological Disorders Drug Targets. Jun, 2008 | Pubmed ID: 18673208 Protecting Against Cerebrovascular Injury: Contributions of 12/15-lipoxygenase to Edema Formation After Transient Focal Ischemia Stroke; a Journal of Cerebral Circulation. Sep, 2008 | Pubmed ID: 18635843 Neuroprotection Via Matrix-trophic Coupling Between Cerebral Endothelial Cells and Neurons Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18495934 A New Penumbra: Transitioning from Injury into Repair After Stroke Nature Medicine. May, 2008 | Pubmed ID: 18463660 Relaxation-compensated Fast Multislice Amide Proton Transfer (APT) Imaging of Acute Ischemic Stroke Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. May, 2008 | Pubmed ID: 18429031 Effects of Neuroglobin Overexpression on Acute Brain Injury and Long-term Outcomes After Focal Cerebral Ischemia Stroke; a Journal of Cerebral Circulation. Jun, 2008 | Pubmed ID: 18403737 Beyond NMDA and AMPA Glutamate Receptors: Emerging Mechanisms for Ionic Imbalance and Cell Death in Stroke Trends in Pharmacological Sciences. May, 2008 | Pubmed ID: 18384889 MMP-9-positive Neutrophil Infiltration is Associated to Blood-brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Apr, 2008 | Pubmed ID: 18323498 Distinct Roles of Matrix Metalloproteases in the Early- and Late-phase Development of Neuropathic Pain Nature Medicine. Mar, 2008 | Pubmed ID: 18264108 Multiphasic Roles for Matrix Metalloproteinases After Stroke Current Opinion in Pharmacology. Feb, 2008 | Pubmed ID: 18226583 Functional MRI of Delayed Chronic Lithium Treatment in Rat Focal Cerebral Ischemia Stroke; a Journal of Cerebral Circulation. Feb, 2008 | Pubmed ID: 18187690 Advances in Emerging Nondrug Therapies for Acute Stroke 2007 Stroke; a Journal of Cerebral Circulation. Feb, 2008 | Pubmed ID: 18187678 Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) Study Stroke; a Journal of Cerebral Circulation. Jan, 2008 | Pubmed ID: 18063832 Novel Lipoxygenase Inhibitors As Neuroprotective Reagents Journal of Neuroscience Research. Mar, 2008 | Pubmed ID: 17960827 Acute Plasmalemma Permeability and Protracted Clearance of Injured Cells After Controlled Cortical Impact in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2008 | Pubmed ID: 17713463 Effect of Neuregulin-1 on Histopathological and Functional Outcome After Controlled Cortical Impact in Mice Journal of Neurotrauma. Dec, 2007 | Pubmed ID: 18159993 Normobaric Hyperoxia Improves Cerebral Blood Flow and Oxygenation, and Inhibits Peri-infarct Depolarizations in Experimental Focal Ischaemia Brain : a Journal of Neurology. Jun, 2007 | Pubmed ID: 17468117 Cell-cell Signaling in the Neurovascular Unit Neurochemical Research. Dec, 2007 | Pubmed ID: 17457674 TNF Alpha and Fas Mediate Tissue Damage and Functional Outcome After Traumatic Brain Injury in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Nov, 2007 | Pubmed ID: 17406655 Induction of Matrix Metalloproteinase, Cytokines and Chemokines in Rat Cortical Astrocytes Exposed to Plasminogen Activators Neuroscience Letters. Apr, 2007 | Pubmed ID: 17386975 Neurovascular Proteases in Brain Injury, Hemorrhage and Remodeling After Stroke Stroke; a Journal of Cerebral Circulation. Feb, 2007 | Pubmed ID: 17261731 Astrocytic Induction of Matrix Metalloproteinase-9 and Edema in Brain Hemorrhage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2007 | Pubmed ID: 16788715 FMRI of Delayed Albumin Treatment During Stroke Recovery in Rats: Implication for Fast Neuronal Habituation in Recovering Brains Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2007 | Pubmed ID: 16736052 Infarct Prediction and Treatment Assessment with MRI-based Algorithms in Experimental Stroke Models Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2007 | Pubmed ID: 16685257 Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by Using Real-time Bioluminescent Imaging Radiology. Dec, 2006 | Pubmed ID: 17114629 Baicalein and 12/15-lipoxygenase in the Ischemic Brain Stroke; a Journal of Cerebral Circulation. Dec, 2006 | Pubmed ID: 17053180 Effects of ApoE Isoforms on Beta-amyloid-induced Matrix Metalloproteinase-9 in Rat Astrocytes Brain Research. Sep, 2006 | Pubmed ID: 16919608 Reduction of Tissue Plasminogen Activator-induced Matrix Metalloproteinase-9 by Simvastatin in Astrocytes Stroke; a Journal of Cerebral Circulation. Jul, 2006 | Pubmed ID: 16741180 Increased Brain Expression of Matrix Metalloproteinase-9 After Ischemic and Hemorrhagic Human Stroke Stroke; a Journal of Cerebral Circulation. Jun, 2006 | Pubmed ID: 16690896 Involvement of Matrix Metalloproteinase in Neuroblast Cell Migration from the Subventricular Zone After Stroke The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16571756 Role of Matrix Metalloproteinases in Delayed Cortical Responses After Stroke Nature Medicine. Apr, 2006 | Pubmed ID: 16565723 Different Strokes for Rodent Folks Nature Methods. Feb, 2006 | Pubmed ID: 16432514 Advances in Stroke Neuroprotection: Hyperoxia and Beyond Neuroimaging Clinics of North America. Aug, 2005 | Pubmed ID: 16360598 Granulocyte Colony-stimulating Factor Enhances Angiogenesis After Focal Cerebral Ischemia Brain Research. Oct, 2005 | Pubmed ID: 16150422 Tissue Plasminogen Activator Promotes Matrix Metalloproteinase-9 Upregulation After Focal Cerebral Ischemia Stroke; a Journal of Cerebral Circulation. Sep, 2005 | Pubmed ID: 16051896 Crossing the Blood-brain Barrier: a Potential Application of Myristoylated Polyarginine for in Vivo Neuroimaging NeuroImage. Oct, 2005 | Pubmed ID: 16040255 Normobaric Hyperoxia Extends the Reperfusion Window in Focal Cerebral Ischemia Annals of Neurology. Apr, 2005 | Pubmed ID: 15786465 A Pilot Study of Normobaric Oxygen Therapy in Acute Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Apr, 2005 | Pubmed ID: 15761201 Measurements of BOLD/CBV Ratio Show Altered FMRI Hemodynamics During Stroke Recovery in Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2005 | Pubmed ID: 15758949 Protective Effects of Statins Involving Both ENOS and TPA in Focal Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2005 | Pubmed ID: 15716855 Proteasome Inhibition Protects HT22 Neuronal Cells from Oxidative Glutamate Toxicity Journal of Neurochemistry. Feb, 2005 | Pubmed ID: 15686484 Exciting, Radical, Suicidal: How Brain Cells Die After Stroke Stroke; a Journal of Cerebral Circulation. Feb, 2005 | Pubmed ID: 15637315 Extracellular Proteolytic Pathophysiology in the Neurovascular Unit After Stroke Neurological Research. Dec, 2004 | Pubmed ID: 15727269 Combination Stroke Therapy: Easy As APC? Nature Medicine. Dec, 2004 | Pubmed ID: 15580249 Mechanisms of Hemorrhagic Transformation After Tissue Plasminogen Activator Reperfusion Therapy for Ischemic Stroke Stroke; a Journal of Cerebral Circulation. Nov, 2004 | Pubmed ID: 15459442 The Neurotoxicity of Tissue Plasminogen Activator? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2004 | Pubmed ID: 15356416 Induction of Caspase-mediated Cell Death by Matrix Metalloproteinases in Cerebral Endothelial Cells After Hypoxia-reoxygenation Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2004 | Pubmed ID: 15241180 Cortical Spreading Depression Activates and Upregulates MMP-9 The Journal of Clinical Investigation. May, 2004 | Pubmed ID: 15146242 Involvement of ERK MAP Kinase in Endoplasmic Reticulum Stress in SH-SY5Y Human Neuroblastoma Cells Journal of Neurochemistry. Apr, 2004 | Pubmed ID: 15030407 Developmentally Regulated Role for Ras-GRFs in Coupling NMDA Glutamate Receptors to Ras, Erk and CREB The EMBO Journal. Apr, 2004 | Pubmed ID: 15029245 TPA and Proteolysis in the Neurovascular Unit Stroke; a Journal of Cerebral Circulation. Feb, 2004 | Pubmed ID: 14757877 Role of Matrix Metalloproteinases in Delayed Neuronal Damage After Transient Global Cerebral Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14736853 Triggers and Mediators of Hemorrhagic Transformation in Cerebral Ischemia Molecular Neurobiology. Dec, 2003 | Pubmed ID: 14709787 Interactions Between P38 Mitogen-activated Protein Kinase and Caspase-3 in Cerebral Endothelial Cell Death After Hypoxia-reoxygenation Stroke; a Journal of Cerebral Circulation. Nov, 2003 | Pubmed ID: 14551401 Lipoprotein Receptor-mediated Induction of Matrix Metalloproteinase by Tissue Plasminogen Activator Nature Medicine. Oct, 2003 | Pubmed ID: 12960961 Antiactin-targeted Immunoliposomes Ameliorate Tissue Plasminogen Activator-induced Hemorrhage After Focal Embolic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2003 | Pubmed ID: 12902833 Essential Role for ERK Mitogen-activated Protein Kinase in Matrix Metalloproteinase-9 Regulation in Rat Cortical Astrocytes Glia. Sep, 2003 | Pubmed ID: 12898704 Mechanisms, Challenges and Opportunities in Stroke Nature Reviews. Neuroscience. May, 2003 | Pubmed ID: 12728267 Neurogenesis and Apoptotic Cell Death Stroke; a Journal of Cerebral Circulation. Feb, 2003 | Pubmed ID: 12574524 Correlation Between Brain Reorganization, Ischemic Damage, and Neurologic Status After Transient Focal Cerebral Ischemia in Rats: a Functional Magnetic Resonance Imaging Study The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003 | Pubmed ID: 12533611 Junctional Complexes of the Blood-brain Barrier: Permeability Changes in Neuroinflammation Progress in Neurobiology. Dec, 2002 | Pubmed ID: 12531232 Downregulation of Matrix Metalloproteinase-9 and Attenuation of Edema Via Inhibition of ERK Mitogen Activated Protein Kinase in Traumatic Brain Injury Journal of Neurotrauma. Nov, 2002 | Pubmed ID: 12490006 Blood-brain Barrier Disruption and Matrix Metalloproteinase-9 Expression During Reperfusion Injury: Mechanical Versus Embolic Focal Ischemia in Spontaneously Hypertensive Rats Stroke; a Journal of Cerebral Circulation. Nov, 2002 | Pubmed ID: 12411666 Gene Transfer of the Caenorhabditis Elegans N-3 Fatty Acid Desaturase Inhibits Neuronal Apoptosis Journal of Neurochemistry. Sep, 2002 | Pubmed ID: 12354283 Rapid Breakdown of Microvascular Barriers and Subsequent Hemorrhagic Transformation After Delayed Recombinant Tissue Plasminogen Activator Treatment in a Rat Embolic Stroke Model Stroke; a Journal of Cerebral Circulation. Aug, 2002 | Pubmed ID: 12154270 Effects of Normobaric Hyperoxia in a Rat Model of Focal Cerebral Ischemia-reperfusion Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2002 | Pubmed ID: 12142571 Extracellular Proteolysis in Brain Injury and Inflammation: Role for Plasminogen Activators and Matrix Metalloproteinases Journal of Neuroscience Research. Jul, 2002 | Pubmed ID: 12111810 Hemoglobin-induced Cytotoxicity in Rat Cerebral Cortical Neurons: Caspase Activation and Oxidative Stress Stroke; a Journal of Cerebral Circulation. Jul, 2002 | Pubmed ID: 12105370 Secretion of Matrix Metalloproteinase-2 and -9 After Mechanical Trauma Injury in Rat Cortical Cultures and Involvement of MAP Kinase Journal of Neurotrauma. May, 2002 | Pubmed ID: 12042096 Mitogen-activated Protein Kinase Inhibition in Traumatic Brain Injury: in Vitro and in Vivo Effects Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2002 | Pubmed ID: 11919515 Normobaric Hyperoxia Reduces MRI Diffusion Abnormalities and Infarct Size in Experimental Stroke Neurology. Mar, 2002 | Pubmed ID: 11914413 Involvement of Matrix Metalloproteinase in Thrombolysis-associated Hemorrhagic Transformation After Embolic Focal Ischemia in Rats Stroke; a Journal of Cerebral Circulation. Mar, 2002 | Pubmed ID: 11872911 Fosforesans Oksijen bağımlı Quenching dayanarak Serebral Kan oksijenasyon Ölçüm Sava Sakadžić1, Emmanuel Roussakis2, Mohammad A. Yaseen1, Emiri T. Mandeville3, Vivek J. Srinivasan1, Ken Arai3, Svetlana Ruvinskaya1, Weicheng Wu1, Anna Devor1,4, Eng H. Lo3, Sergei A. Vinogradov2, David A. Boas1 1Optics Division, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 2Department of Biochemistry and Biophysics, University of Pennsylvania, 3Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, 4Departments of Neurosciences and Radiology, University of California JoVE 1694 Neurowissenschaften
Fosforesans Oksijen bağımlı Quenching dayanarak Serebral Kan oksijenasyon Ölçüm Sava Sakadžić1, Emmanuel Roussakis2, Mohammad A. Yaseen1, Emiri T. Mandeville3, Vivek J. Srinivasan1, Ken Arai3, Svetlana Ruvinskaya1, Weicheng Wu1, Anna Devor1,4, Eng H. Lo3, Sergei A. Vinogradov2, David A. Boas1 1Optics Division, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 2Department of Biochemistry and Biophysics, University of Pennsylvania, 3Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, 4Departments of Neurosciences and Radiology, University of California JoVE 1694 Neurowissenschaften