Jack Greenblatt Banting and Best Department of Medical Research, Donnelly Centre University of Toronto Biography Publications Institution JoVE Articles Jack Greenblatt has not added a biography. If you are Jack Greenblatt and would like to personalize this page please email our Author Liaison for assistance. Publications Interaction Landscape of Membrane-protein Complexes in Saccharomyces Cerevisiae Nature. Sep, 2012 | Pubmed ID: 22940862 Hsp110 is Required for Spindle Length Control The Journal of Cell Biology. Aug, 2012 | Pubmed ID: 22908312 Control of the RNA Polymerase II Phosphorylation State in Promoter Regions by CTD Interaction Domain-containing Proteins RPRD1A and RPRD1B Transcription. Sep-Oct, 2011 | Pubmed ID: 22231121 Genetic Interaction Maps in Escherichia Coli Reveal Functional Crosstalk Among Cell Envelope Biogenesis Pathways PLoS Genetics. Nov, 2011 | Pubmed ID: 22125496 Identification of Mammalian Protein Complexes by Lentiviral-based Affinity Purification and Mass Spectrometry Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21877275 Array-based Synthetic Genetic Screens to Map Bacterial Pathways and Functional Networks in Escherichia Coli Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21815091 Ribosome-dependent ATPase Interacts with Conserved Membrane Protein in Escherichia Coli to Modulate Protein Synthesis and Oxidative Phosphorylation PloS One. 2011 | Pubmed ID: 21556145 OrthoNets: Simultaneous Visual Analysis of Orthologs and Their Interaction Neighborhoods Across Different Organisms Bioinformatics (Oxford, England). Mar, 2011 | Pubmed ID: 21257609 A Dual Function of the CRISPR-Cas System in Bacterial Antivirus Immunity and DNA Repair Molecular Microbiology. Jan, 2011 | Pubmed ID: 21219465 DAnCER: Disease-annotated Chromatin Epigenetics Resource Nucleic Acids Research. Jan, 2011 | Pubmed ID: 20876685 Defining the Budding Yeast Chromatin-associated Interactome Molecular Systems Biology. Dec, 2010 | Pubmed ID: 21179020 Expanding the Landscape of Chromatin Modification (CM)-related Functional Domains and Genes in Human PloS One. 2010 | Pubmed ID: 21124763 Structure of a SLC26 Anion Transporter STAS Domain in Complex with Acyl Carrier Protein: Implications for E. Coli YchM in Fatty Acid Metabolism Structure (London, England : 1993). Nov, 2010 | Pubmed ID: 21070944 Epistatic Relationships Reveal the Functional Organization of Yeast Transcription Factors Molecular Systems Biology. Oct, 2010 | Pubmed ID: 20959818 The Program for Processing Newly Synthesized Histones H3.1 and H4 Nature Structural & Molecular Biology. Nov, 2010 | Pubmed ID: 20953179 The Evolutionary Landscape of the Chromatin Modification Machinery Reveals Lineage Specific Gains, Expansions, and Losses Proteins. Jul, 2010 | Pubmed ID: 20455264 A Lentiviral Functional Proteomics Approach Identifies Chromatin Remodeling Complexes Important for the Induction of Pluripotency Molecular & Cellular Proteomics : MCP. May, 2010 | Pubmed ID: 20305087 An Acetylated Form of Histone H2A.Z Regulates Chromosome Architecture in Schizosaccharomyces Pombe Nature Structural & Molecular Biology. Dec, 2009 | Pubmed ID: 19915592 A Systematic Characterization of Cwc21, the Yeast Ortholog of the Human Spliceosomal Protein SRm300 RNA (New York, N.Y.). Dec, 2009 | Pubmed ID: 19789211 Systems-level Approaches for Identifying and Analyzing Genetic Interaction Networks in Escherichia Coli and Extensions to Other Prokaryotes Molecular BioSystems. Dec, 2009 | Pubmed ID: 19763343 Two-color Cell Array Screen Reveals Interdependent Roles for Histone Chaperones and a Chromatin Boundary Regulator in Histone Gene Repression Molecular Cell. Aug, 2009 | Pubmed ID: 19683497 Sequential Peptide Affinity Purification System for the Systematic Isolation and Identification of Protein Complexes from Escherichia Coli Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19544035 An Atlas of Chaperone-protein Interactions in Saccharomyces Cerevisiae: Implications to Protein Folding Pathways in the Cell Molecular Systems Biology. 2009 | Pubmed ID: 19536198 Systematic Characterization of the Protein Interaction Network and Protein Complexes in Saccharomyces Cerevisiae Using Tandem Affinity Purification and Mass Spectrometry Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19521826 Global Functional Atlas of Escherichia Coli Encompassing Previously Uncharacterized Proteins PLoS Biology. Apr, 2009 | Pubmed ID: 19402753 Conserved Network of Proteins Essential for Bacterial Viability Journal of Bacteriology. Aug, 2009 | Pubmed ID: 19376873 Control of Transcriptional Elongation and Cotranscriptional Histone Modification by the Yeast BUR Kinase Substrate Spt5 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19365074 Stable Complex Formation Between HIV Rev and the Nucleosome Assembly Protein, NAP1, Affects Rev Function Virology. May, 2009 | Pubmed ID: 19339032 Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 is Required for Transporter/receptor Sorting in the Multivesicular Body Pathway PloS One. 2009 | Pubmed ID: 19165343 Local Coherence in Genetic Interaction Patterns Reveals Prevalent Functional Versatility Bioinformatics (Oxford, England). Oct, 2008 | Pubmed ID: 18718945 Biosynthesis of the Respiratory Formate Dehydrogenases from Escherichia Coli: Characterization of the FdhE Protein Archives of Microbiology. Dec, 2008 | Pubmed ID: 18716757 ESGA: E. Coli Synthetic Genetic Array Analysis Nature Methods. Sep, 2008 | Pubmed ID: 18677321 A Histone Code for Chromatin Assembly Cell. Jul, 2008 | Pubmed ID: 18662534 Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109 Molecular and Cellular Biology. Jul, 2008 | Pubmed ID: 18458063 Transcription Termination: Pulling out All the Stops Cell. Mar, 2008 | Pubmed ID: 18358802 The Glc7 Phosphatase Subunit of the Cleavage and Polyadenylation Factor is Essential for Transcription Termination on SnoRNA Genes Molecular Cell. Mar, 2008 | Pubmed ID: 18342605 Pax7 Activates Myogenic Genes by Recruitment of a Histone Methyltransferase Complex Nature Cell Biology. Jan, 2008 | Pubmed ID: 18066051 Interacting Proteins Rtt109 and Vps75 Affect the Efficiency of Non-homologous End-joining in Saccharomyces Cerevisiae Archives of Biochemistry and Biophysics. Jan, 2008 | Pubmed ID: 18036332 Genomic Location of the Human RNA Polymerase II General Machinery: Evidence for a Role of TFIIF and Rpb7 at Both Early and Late Stages of Transcription The Biochemical Journal. Jan, 2008 | Pubmed ID: 17848138 Examining Protein Protein Interactions Using Endogenously Tagged Yeast Arrays: the Cross-and-capture System Genome Research. Dec, 2007 | Pubmed ID: 17989249 Association with the Origin Recognition Complex Suggests a Novel Role for Histone Acetyltransferase Hat1p/Hat2p BMC Biology. 2007 | Pubmed ID: 17880717 The Minimum Information Required for Reporting a Molecular Interaction Experiment (MIMIx) Nature Biotechnology. Aug, 2007 | Pubmed ID: 17687370 Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme Molecular Cell. Jul, 2007 | Pubmed ID: 17643375 Identifying Functional Modules in the Physical Interactome of Saccharomyces Cerevisiae Proteomics. Mar, 2007 | Pubmed ID: 17370254 Functional Dissection of Protein Complexes Involved in Yeast Chromosome Biology Using a Genetic Interaction Map Nature. Apr, 2007 | Pubmed ID: 17314980 Toward a Comprehensive Atlas of the Physical Interactome of Saccharomyces Cerevisiae Molecular & Cellular Proteomics : MCP. Mar, 2007 | Pubmed ID: 17200106 The RNA Polymerase II Kinase Ctk1 Regulates Positioning of a 5' Histone Methylation Boundary Along Genes Molecular and Cellular Biology. Jan, 2007 | Pubmed ID: 17088384 Investigating the in Vivo Activity of the DeaD Protein Using Protein-protein Interactions and the Translational Activity of Structured Chloramphenicol Acetyltransferase MRNAs Journal of Cellular Biochemistry. Feb, 2007 | Pubmed ID: 16983699 PIPE: a Protein-protein Interaction Prediction Engine Based on the Re-occurring Short Polypeptide Sequences Between Known Interacting Protein Pairs BMC Bioinformatics. 2006 | Pubmed ID: 16872538 Systems-level Analyses Identify Extensive Coupling Among Gene Expression Machines Molecular Systems Biology. 2006 | Pubmed ID: 16738550 A Genome-wide Screen Identifies the Evolutionarily Conserved KEOPS Complex As a Telomere Regulator Cell. Mar, 2006 | Pubmed ID: 16564010 Global Landscape of Protein Complexes in the Yeast Saccharomyces Cerevisiae Nature. Mar, 2006 | Pubmed ID: 16554755 The Saccharomyces Cerevisiae Histone H2A Variant Htz1 is Acetylated by NuA4 Genes & Development. Mar, 2006 | Pubmed ID: 16543219 Interactions of the Escherichia Coli Hydrogenase Biosynthetic Proteins: HybG Complex Formation FEBS Letters. Jan, 2006 | Pubmed ID: 16412426 Formation of a Distinctive Complex Between the Inducible Bacterial Lysine Decarboxylase and a Novel AAA+ ATPase The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16301313 A Phosphatase Complex That Dephosphorylates GammaH2AX Regulates DNA Damage Checkpoint Recovery Nature. Jan, 2006 | Pubmed ID: 16299494 Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex Cell. Nov, 2005 | Pubmed ID: 16286008 Exploration of the Function and Organization of the Yeast Early Secretory Pathway Through an Epistatic Miniarray Profile Cell. Nov, 2005 | Pubmed ID: 16269340 Identification and Characterization of Elf1, a Conserved Transcription Elongation Factor in Saccharomyces Cerevisiae Molecular and Cellular Biology. Nov, 2005 | Pubmed ID: 16260625 BUR Kinase Selectively Regulates H3 K4 Trimethylation and H2B Ubiquitylation Through Recruitment of the PAF Elongation Complex Current Biology : CB. Aug, 2005 | Pubmed ID: 16040246 Esf2p, a U3-associated Factor Required for Small-subunit Processome Assembly and Compaction Molecular and Cellular Biology. Jul, 2005 | Pubmed ID: 15964808 The Highly Conserved Glutamic Acid 791 of Rpb2 is Involved in the Binding of NTP and Mg(B) in the Active Center of Human RNA Polymerase II Nucleic Acids Research. 2005 | Pubmed ID: 15886393 Navigating the Chaperone Network: an Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone Cell. Mar, 2005 | Pubmed ID: 15766533 Interactions of the HIV-1 Tat and RAP74 Proteins with the RNA Polymerase II CTD Phosphatase FCP1 Biochemistry. Mar, 2005 | Pubmed ID: 15723517 Maintenance of Low Histone Ubiquitylation by Ubp10 Correlates with Telomere-proximal Sir2 Association and Gene Silencing Molecular Cell. Feb, 2005 | Pubmed ID: 15721261 The Shwachman-Bodian-Diamond Syndrome Protein Family is Involved in RNA Metabolism The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15701634 Interaction Network Containing Conserved and Essential Protein Complexes in Escherichia Coli Nature. Feb, 2005 | Pubmed ID: 15690043 H2B Ubiquitin Protease Ubp8 and Sgf11 Constitute a Discrete Functional Module Within the Saccharomyces Cerevisiae SAGA Complex Molecular and Cellular Biology. Feb, 2005 | Pubmed ID: 15657441 Histone H2B Ubiquitylation is Associated with Elongating RNA Polymerase II Molecular and Cellular Biology. Jan, 2005 | Pubmed ID: 15632065 A Role for SlyD in the Escherichia Coli Hydrogenase Biosynthetic Pathway The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15569666 Interaction of Fcp1 Phosphatase with Elongating RNA Polymerase II Holoenzyme, Enzymatic Mechanism of Action, and Genetic Interaction with Elongator The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15563457 Proteasome Involvement in the Repair of DNA Double-strand Breaks Molecular Cell. Dec, 2004 | Pubmed ID: 15610744 INO80 and Gamma-H2AX Interaction Links ATP-dependent Chromatin Remodeling to DNA Damage Repair Cell. Dec, 2004 | Pubmed ID: 15607974 The Functional Landscape of Mouse Gene Expression Journal of Biology. 2004 | Pubmed ID: 15588312 The Yeast Rat1 Exonuclease Promotes Transcription Termination by RNA Polymerase II Nature. Nov, 2004 | Pubmed ID: 15565157 Regulation of Chromosome Stability by the Histone H2A Variant Htz1, the Swr1 Chromatin Remodeling Complex, and the Histone Acetyltransferase NuA4 Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15353583 RPAP1, a Novel Human RNA Polymerase II-associated Protein Affinity Purified with Recombinant Wild-type and Mutated Polymerase Subunits Molecular and Cellular Biology. Aug, 2004 | Pubmed ID: 15282305 Sequential Peptide Affinity (SPA) System for the Identification of Mammalian and Bacterial Protein Complexes Journal of Proteome Research. May-Jun, 2004 | Pubmed ID: 15253427 Exploration of Essential Gene Functions Via Titratable Promoter Alleles Cell. Jul, 2004 | Pubmed ID: 15242642 Bromodomain Factor 1 (Bdf1) is Phosphorylated by Protein Kinase CK2 Molecular and Cellular Biology. Jun, 2004 | Pubmed ID: 15143168 Dephosphorylation of RNA Polymerase I by Fcp1p is Required for Efficient RRNA Synthesis The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15073185 ESF1 is Required for 18S RRNA Synthesis in Saccharomyces Cerevisiae Nucleic Acids Research. 2004 | Pubmed ID: 15056729 Global Mapping of the Yeast Genetic Interaction Network Science (New York, N.Y.). Feb, 2004 | Pubmed ID: 14764870 High-definition Macromolecular Composition of Yeast RNA-processing Complexes Molecular Cell. Jan, 2004 | Pubmed ID: 14759368 Transitions in RNA Polymerase II Elongation Complexes at the 3' Ends of Genes The EMBO Journal. Jan, 2004 | Pubmed ID: 14739930 The Ctf13-30/CTF13 Genomic Haploinsufficiency Modifier Screen Identifies the Yeast Chromatin Remodeling Complex RSC, Which is Required for the Establishment of Sister Chromatid Cohesion Molecular and Cellular Biology. Feb, 2004 | Pubmed ID: 14729968 Purification and Assay of Saccharomyces Cerevisiae Phosphatase That Acts on the C-terminal Domain of the Largest Subunit of RNA Polymerase II Methods in Enzymology. 2003 | Pubmed ID: 14712662 A Snf2 Family ATPase Complex Required for Recruitment of the Histone H2A Variant Htz1 Molecular Cell. Dec, 2003 | Pubmed ID: 14690608 A Bayesian Networks Approach for Predicting Protein-protein Interactions from Genomic Data Science (New York, N.Y.). Oct, 2003 | Pubmed ID: 14564010 A Panoramic View of Yeast Noncoding RNA Processing Cell. Jun, 2003 | Pubmed ID: 12837249 Organization and Function of APT, a Subcomplex of the Yeast Cleavage and Polyadenylation Factor Involved in the Formation of MRNA and Small Nucleolar RNA 3'-ends The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12819204 Protein Profiling with Epstein-Barr Nuclear Antigen-1 Reveals an Interaction with the Herpesvirus-associated Ubiquitin-specific Protease HAUSP/USP7 The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12783858 Methylation of Histone H3 by Set2 in Saccharomyces Cerevisiae is Linked to Transcriptional Elongation by RNA Polymerase II Molecular and Cellular Biology. Jun, 2003 | Pubmed ID: 12773564 NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA Polymerase II Carboxyl-terminal Domain Phosphatase FCP1 Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12732728 The Paf1 Complex is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation Molecular Cell. Mar, 2003 | Pubmed ID: 12667454 Specific Homeodomain-DNA Interactions Are Required for HOX11-mediated Transformation Blood. Jun, 2003 | Pubmed ID: 12586625 Solution Structure of the Carboxyl-terminal Domain of RAP74 and NMR Characterization of the FCP1-binding Sites of RAP74 and Human TFIIB Biochemistry. Feb, 2003 | Pubmed ID: 12578358 Bre1, an E3 Ubiquitin Ligase Required for Recruitment and Substrate Selection of Rad6 at a Promoter Molecular Cell. Jan, 2003 | Pubmed ID: 12535539 Bridging Structural Biology and Genomics: Assessing Protein Interaction Data with Known Complexes Trends in Genetics : TIG. Oct, 2002 | Pubmed ID: 12350343 RNA Polymerase II Elongation Factors of Saccharomyces Cerevisiae: a Targeted Proteomics Approach Molecular and Cellular Biology. Oct, 2002 | Pubmed ID: 12242279 Regulation of Transcription Elongation by Phosphorylation Biochimica Et Biophysica Acta. Sep, 2002 | Pubmed ID: 12213657 Evidence That the KH RNA-binding Domains Influence the Action of the E. Coli NusA Protein Journal of Molecular Biology. May, 2002 | Pubmed ID: 12083510 COMPASS, a Histone H3 (Lysine 4) Methyltransferase Required for Telomeric Silencing of Gene Expression The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11805083 Identifiering av proteinkomplex i Mohan Babu1,2, Olga Kagan1, Hongbo Guo1, Jack Greenblatt1,3, Andrew Emili1,3 1Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, 2Deparment of Biochemistry, Research and Innovation Centre, University of Regina, 3Department of Medical Genetics and Microbiology, University of Toronto JoVE 4057 Biologie Kartläggning Bakteriella funktionella nätverk och vägar i Alla Gagarinova*1, Mohan Babu*2,3, Jack Greenblatt1,2, Andrew Emili1,2 1Department of Molecular Genetics, University of Toronto, 2Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, 3Department of Biochemistry, Research and Innovation Centre, University of Regina JoVE 4056 Biologie
Identifiering av proteinkomplex i Mohan Babu1,2, Olga Kagan1, Hongbo Guo1, Jack Greenblatt1,3, Andrew Emili1,3 1Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, 2Deparment of Biochemistry, Research and Innovation Centre, University of Regina, 3Department of Medical Genetics and Microbiology, University of Toronto JoVE 4057 Biologie
Kartläggning Bakteriella funktionella nätverk och vägar i Alla Gagarinova*1, Mohan Babu*2,3, Jack Greenblatt1,2, Andrew Emili1,2 1Department of Molecular Genetics, University of Toronto, 2Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, 3Department of Biochemistry, Research and Innovation Centre, University of Regina JoVE 4056 Biologie