Stephen J. Clarke Department of Medicine Concord Repatriation General Hospital Biography Publications Institution JoVE Articles Stephen J. Clarke has not added a biography. If you are Stephen J. Clarke and would like to personalize this page please email our Author Liaison for assistance. Publications Src Tyrosine Kinase Phosphorylation of Nuclear Receptor HNF4α Correlates with Isoform-specific Loss of HNF4α in Human Colon Cancer Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308320 Clinicopathological Correlates and Prognostic Significance of Glutathione S-transferase Pi Expression in 468 Patients After Potentially Curative Resection of Node-positive Colonic Cancer Histopathology. Dec, 2011 | Pubmed ID: 22175886 Systemic Inflammation and Prediction of Chemotherapy Outcomes in Patients Receiving Docetaxel for Advanced Cancer Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Oct, 2011 | Pubmed ID: 21986674 An Update on Ethnic Differences in Drug Metabolism and Toxicity from Anti-cancer Drugs Expert Opinion on Drug Metabolism & Toxicology. Nov, 2011 | Pubmed ID: 21950349 Clinical Pharmacology of Chemotherapy Agents in Older People with Cancer Current Gerontology and Geriatrics Research. 2011 | Pubmed ID: 21845189 Proteomic Comparison of Colorectal Tumours and Non-neoplastic Mucosa from Paired Patient Samples Using ITRAQ Mass Spectrometry Molecular BioSystems. Nov, 2011 | Pubmed ID: 21808808 Medication Adherence Among Rural, Low-income Hypertensive Adults: a Randomized Trial of a Multimedia Community-based Intervention American Journal of Health Promotion : AJHP. Jul-Aug, 2011 | Pubmed ID: 21721962 Effect of Medical Qigong on Cognitive Function, Quality of Life, and a Biomarker of Inflammation in Cancer Patients: a Randomized Controlled Trial Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Jun, 2011 | Pubmed ID: 21688163 Single-agent Irinotecan or 5-fluorouracil and Leucovorin (FOLFIRI) As Second-line Chemotherapy for Advanced Colorectal Cancer; Results of a Randomised Phase II Study (DaVINCI) and Meta-analysis European Journal of Cancer (Oxford, England : 1990). Aug, 2011 | Pubmed ID: 21665462 Extrahepatic Cancer Suppresses Nuclear Receptor-regulated Drug Metabolism Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21498392 Supporting Treatment Decision Making in Advanced Cancer: a Randomized Trial of a Decision Aid for Patients with Advanced Colorectal Cancer Considering Chemotherapy Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2011 | Pubmed ID: 21483008 Pharmacometabonomic Profiling As a Predictor of Toxicity in Patients with Inoperable Colorectal Cancer Treated with Capecitabine Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21415219 Reporting Clinical Trial Information: Colorectal Cancer Trials at Sydney Cancer Centre Internal Medicine Journal. Feb, 2011 | Pubmed ID: 21299781 Patient and Oncologist Estimates of Survival in Advanced Cancer Patients Psycho-oncology. Feb, 2011 | Pubmed ID: 20878829 Clinical, Laboratory and Molecular Factors Predicting Chemotherapy Efficacy and Toxicity in Colorectal Cancer Critical Reviews in Oncology/hematology. Sep, 2011 | Pubmed ID: 20719530 Liver Membrane Proteome Glycosylation Changes in Mice Bearing an Extra-hepatic Tumor Molecular & Cellular Proteomics : MCP. Sep, 2011 | Pubmed ID: 20167946 High Blood Neutrophil-to-lymphocyte Ratio is an Indicator of Poor Prognosis in Malignant Mesothelioma Patients Undergoing Systemic Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2010 | Pubmed ID: 20956618 Taking Less Than Prescribed: Medication Nonadherence and Provider-patient Relationships in Lower-income, Rural Minority Adults with Hypertension Journal of Clinical Hypertension (Greenwich, Conn.). Sep, 2010 | Pubmed ID: 20883231 Clinical Trial Information As a Measure of Quality Cancer Care Journal of Oncology Practice / American Society of Clinical Oncology. May, 2010 | Pubmed ID: 20808563 Clinicopathological Correlates and Prognostic Significance of Maspin Expression in 450 Patients After Potentially Curative Resection of Node-positive Colonic Cancer Histopathology. Feb, 2010 | Pubmed ID: 20459532 Surface Antigen Profiling of Colorectal Cancer Using Antibody Microarrays with Fluorescence Multiplexing Journal of Immunological Methods. Apr, 2010 | Pubmed ID: 20156443 The Alternatively Spliced Murine Pregnane X Receptor Isoform, MPXR(delta171-211) Exhibits a Repressive Action The International Journal of Biochemistry & Cell Biology. May, 2010 | Pubmed ID: 20060928 Predictive Biomarkers of Clinical Response to Targeted Antibodies in Colorectal Cancer Current Opinion in Molecular Therapeutics. Dec, 2009 | Pubmed ID: 20072938 A Novel Approach to Investigate the Subcellular Distribution of Nuclear Receptors in Vivo Nuclear Receptor Signaling. 2009 | Pubmed ID: 19471583 Inflammatory (B) Symptoms Are Independent Predictors of Myelosuppression from Chemotherapy in Non-Hodgkin Lymphoma (NHL) Patients--analysis of Data from a British National Lymphoma Investigation Phase III Trial Comparing CHOP to PMitCEBO BMC Cancer. 2009 | Pubmed ID: 19450285 Eligibility of Patients with Advanced Non-small Cell Lung Cancer for Phase III Chemotherapy Trials BMC Cancer. 2009 | Pubmed ID: 19402889 Ethnic Differences in Drug Metabolism and Toxicity from Chemotherapy Expert Opinion on Drug Metabolism & Toxicology. Mar, 2009 | Pubmed ID: 19331590 Systemic Inflammatory Response Predicts Prognosis in Patients with Advanced-stage Colorectal Cancer Clinical Colorectal Cancer. Sep, 2008 | Pubmed ID: 18794066 Potential Regional Differences for the Tolerability Profiles of Fluoropyrimidines Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2008 | Pubmed ID: 18445840 Inflammation and CYP3A4-mediated Drug Metabolism in Advanced Cancer: Impact and Implications for Chemotherapeutic Drug Dosing Expert Opinion on Drug Metabolism & Toxicology. Feb, 2008 | Pubmed ID: 18248309 Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphisms and Toxicity to Capecitabine in Advanced Colorectal Cancer Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18245544 Regulation of Drug-metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer Drug Metabolism and Disposition: the Biological Fate of Chemicals. Feb, 2008 | Pubmed ID: 18218849 The Development of Multiple Reaction Monitoring Assays for Liver-derived Plasma Proteins Proteomics. Clinical Applications. Dec, 2007 | Pubmed ID: 21136656 Nutrition Intervention Using an Eicosapentaenoic Acid (EPA)-containing Supplement in Patients with Advanced Colorectal Cancer. Effects on Nutritional and Inflammatory Status: a Phase II Trial Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Mar, 2007 | Pubmed ID: 17021855 Altered Deoxyuridine and Thymidine in Plasma Following Capecitabine Treatment in Colorectal Cancer Patients British Journal of Clinical Pharmacology. Jan, 2007 | Pubmed ID: 16827816 Prognostic Factors Predictive of Response and Survival to a Modified FOLFOX Regimen: Importance of an Increased Neutrophil Count Clinical Colorectal Cancer. Nov, 2006 | Pubmed ID: 17241514 Transcriptional Repression of Hepatic Cytochrome P450 3A4 Gene in the Presence of Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2006 | Pubmed ID: 17189422 Evaluation of Nutritional and Inflammatory Status of Advanced Colorectal Cancer Patients and Its Correlation with Survival Nutrition and Cancer. 2006 | Pubmed ID: 16965244 Relationship of Hepatic Functional Imaging to Irinotecan Pharmacokinetics and Genetic Parameters of Drug Elimination Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2006 | Pubmed ID: 16896007 Advances in the Adjuvant Treatment of Colorectal Cancer ANZ Journal of Surgery. May, 2006 | Pubmed ID: 16768699 Predicting the Toxicity of Weekly Docetaxel in Advanced Cancer Clinical Pharmacokinetics. 2006 | Pubmed ID: 16719542 Nutritional Assessment in Cancer: Comparing the Mini-Nutritional Assessment (MNA) with the Scored Patient-Generated Subjective Global Assessment (PGSGA) Nutrition and Cancer. 2005 | Pubmed ID: 16351506 A Phase I/II Study of Pemetrexed and Vinorelbine in Patients with Non-small Cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Sep, 2005 | Pubmed ID: 15923057 Management of Chemotherapy-induced Nausea, Vomiting, Oral Mucositis, and Diarrhoea The Lancet Oncology. Feb, 2005 | Pubmed ID: 15683818 Factors Affecting Cytochrome P-450 3A Activity in Cancer Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2004 | Pubmed ID: 15623611 Population Pharmacokinetics of Raltitrexed in Patients with Advanced Solid Tumours British Journal of Clinical Pharmacology. Apr, 2004 | Pubmed ID: 15025739 Population Pharmacokinetics of Weekly Docetaxel in Patients with Advanced Cancer British Journal of Clinical Pharmacology. Jan, 2004 | Pubmed ID: 14678339 Baseline Nutritional Assessment in Advanced Cancer Patients Receiving Palliative Chemotherapy Nutrition and Cancer. 2003 | Pubmed ID: 14690790 Inflammatory Response: an Unrecognised Source of Variability in the Pharmacokinetics and Pharmacodynamics of Cancer Chemotherapy The Lancet Oncology. Apr, 2003 | Pubmed ID: 12681266 Thymidylate Synthase Inhibitors Cancer Chemotherapy and Biological Response Modifiers. 2002 | Pubmed ID: 12703198 Pemetrexed: Single-agent and Combination Phase I Study Overview Seminars in Oncology. Dec, 2002 | Pubmed ID: 12571806 Use of the Internet by Oncology Patients: Its Effect on the Doctor-patient Relationship The Medical Journal of Australia. Oct, 2002 | Pubmed ID: 12358586 Life-threatening Anaphylactoid Reaction to Amifostine Used with Concurrent Chemoradiotherapy for Nasopharyngeal Cancer in a Patient with Dermatomyositis: a Case Report with Literature Review Anti-cancer Drugs. Mar, 2002 | Pubmed ID: 11984077 कोलोरेक्टल कैंसर कोशिका की सतह प्रोटीन रूपरेखा का प्रयोग एक एंटीबॉडी माइक्रोएरे और प्रतिदीप्ति बहुसंकेतन Jerry Zhou1, Larissa Belov1, Michael J. Solomon2, Charles Chan3, Stephen J. Clarke4, Richard I. Christopherson1 1School of Molecular Bioscience, University of Sydney, 2Department of Surgery, Royal Prince Alfred Hospital, 3Department of Anatomical Pathology, Department of Anatomical Pathology, 4Department of Medicine, Concord Repatriation General Hospital JoVE 3322 Immunologie und Infektion
कोलोरेक्टल कैंसर कोशिका की सतह प्रोटीन रूपरेखा का प्रयोग एक एंटीबॉडी माइक्रोएरे और प्रतिदीप्ति बहुसंकेतन Jerry Zhou1, Larissa Belov1, Michael J. Solomon2, Charles Chan3, Stephen J. Clarke4, Richard I. Christopherson1 1School of Molecular Bioscience, University of Sydney, 2Department of Surgery, Royal Prince Alfred Hospital, 3Department of Anatomical Pathology, Department of Anatomical Pathology, 4Department of Medicine, Concord Repatriation General Hospital JoVE 3322 Immunologie und Infektion