Stephen Rittenhouse Antibacterial Discovery Performance Unit GlaxoSmithKline Biography Publications Institution JoVE Articles Stephen Rittenhouse has not added a biography. If you are Stephen Rittenhouse and would like to personalize this page please email our Author Liaison for assistance. Publications In Vitro Antimicrobial Activity of S-649266, a Catechol-substituted Siderophore Cephalosporin, when Tested Against Non-fermenting Gram-negative Bacteria The Journal of Antimicrobial Chemotherapy. Mar, 2016 | Pubmed ID: 26645269 In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, Against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains Antimicrobial Agents and Chemotherapy. Feb, 2016 | Pubmed ID: 26574013 Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 Against Streptococcus Pneumoniae, Haemophilus Influenzae, and Staphylococcus Aureus in Rodent Models of Infection Antimicrobial Agents and Chemotherapy. Oct, 2015 | Pubmed ID: 26482300 Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops During Treatment of Complicated Urinary Tract Infections Antimicrobial Agents and Chemotherapy. Jan, 2015 | Pubmed ID: 25348524 強力な抗菌剤の細菌をターゲットとして新規のアミノ多 IIA Topoisomerases を入力します。 Bioorganic & Medicinal Chemistry Letters. Dec, 2011 | Pubmed ID: 22047689 細菌のタイプ IIA Topoisomerases ターゲットと強力な抗菌剤としての新規シクロヘキシル アミド。 Bioorganic & Medicinal Chemistry Letters. Dec, 2011 | Pubmed ID: 22030032 Challenges of Antibacterial Discovery Revisited Annals of the New York Academy of Sciences. Dec, 2010 | Pubmed ID: 21058956 A Rapid Microtiter Plate Assay for Measuring the Effect of Compounds on Staphylococcus Aureus Membrane Potential Journal of Microbiological Methods. Nov, 2010 | Pubmed ID: 20801170 Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. Dec, 2008 | Pubmed ID: 18838584 Stepwise Exposure of Staphylococcus Aureus to Pleuromutilins is Associated with Stepwise Acquisition of Mutations in RplC and Minimally Affects Susceptibility to Retapamulin Antimicrobial Agents and Chemotherapy. Jun, 2007 | Pubmed ID: 17404009 Use of the Surgical Wound Infection Model to Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic Antimicrobial Agents and Chemotherapy. Nov, 2006 | Pubmed ID: 17065626 Selection of Retapamulin, a Novel Pleuromutilin for Topical Use Antimicrobial Agents and Chemotherapy. Nov, 2006 | Pubmed ID: 17065625 Definition of the Heterocyclic Pharmacophore of Bacterial Methionyl TRNA Synthetase Inhibitors: Potent Antibacterially Active Non-quinolone Analogues Bioorganic & Medicinal Chemistry Letters. Aug, 2004 | Pubmed ID: 15225702 New Benzylidenethiazolidinediones As Antibacterial Agents Bioorganic & Medicinal Chemistry Letters. Nov, 2003 | Pubmed ID: 14552776 Variable Sensitivity to Bacterial Methionyl-tRNA Synthetase Inhibitors Reveals Subpopulations of Streptococcus Pneumoniae with Two Distinct Methionyl-tRNA Synthetase Genes Antimicrobial Agents and Chemotherapy. Jun, 2003 | Pubmed ID: 12760849 Indole Naphthyridinones As Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK Journal of Medicinal Chemistry. Apr, 2003 | Pubmed ID: 12699381 Conformational Restriction of Methionyl TRNA Synthetase Inhibitors Leading to Analogues with Potent Inhibition and Excellent Gram-positive Antibacterial Activity Bioorganic & Medicinal Chemistry Letters. Apr, 2003 | Pubmed ID: 12657260 Optimisation of Aryl Substitution Leading to Potent Methionyl TRNA Synthetase Inhibitors with Excellent Gram-positive Antibacterial Activity Bioorganic & Medicinal Chemistry Letters. Feb, 2003 | Pubmed ID: 12639554 Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. Nov, 2002 | Pubmed ID: 12384334 Discovery of a Novel and Potent Class of FabI-directed Antibacterial Agents Antimicrobial Agents and Chemotherapy. Oct, 2002 | Pubmed ID: 12234833 Discovery of Aminopyridine-based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI) Journal of Medicinal Chemistry. Jul, 2002 | Pubmed ID: 12109908 Identification of a Series of Tricyclic Natural Products As Potent Broad-spectrum Inhibitors of Metallo-beta-lactamases Antimicrobial Agents and Chemotherapy. Jun, 2002 | Pubmed ID: 12019104 Nanomolar Inhibitors of Staphylococcus Aureus Methionyl TRNA Synthetase with Potent Antibacterial Activity Against Gram-positive Pathogens Journal of Medicinal Chemistry. May, 2002 | Pubmed ID: 11985462 免疫担当げっ歯類で堅牢な肺炎モデルはに対して抗菌有効性を評価するために Jennifer L. Hoover1, Thomas F. Lewandowski1, Cindy L. Mininger1, Christine M. Singley1, Scott Sucoloski1, Stephen Rittenhouse1 1Antibacterial Discovery Performance Unit, GlaxoSmithKline Immunologie und Infektion
免疫担当げっ歯類で堅牢な肺炎モデルはに対して抗菌有効性を評価するために Jennifer L. Hoover1, Thomas F. Lewandowski1, Cindy L. Mininger1, Christine M. Singley1, Scott Sucoloski1, Stephen Rittenhouse1 1Antibacterial Discovery Performance Unit, GlaxoSmithKline Immunologie und Infektion