Tarjei S. Mikkelsen Broad Institute Biography Publications Institution JoVE Articles Tarjei S. Mikkelsen has not added a biography. If you are Tarjei S. Mikkelsen and would like to personalize this page please email our Author Liaison for assistance. Publications Perturbation of M6A Writers Reveals Two Distinct Classes of MRNA Methylation at Internal and 5' Sites Cell Reports. Jul, 2014 | Pubmed ID: 24981863 Comprehensive Mutational Scanning of a Kinase in Vivo Reveals Substrate-dependent Fitness Landscapes Nucleic Acids Research. Oct, 2014 | Pubmed ID: 24914046 The Regulatory Landscape of Osteogenic Differentiation Stem Cells (Dayton, Ohio). Jun, 2014 | Pubmed ID: 24898411 Analysis of the Effects of Five Factors Relevant to in Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput MRNA-profiling PloS One. 2014 | Pubmed ID: 24816923 ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myoblast Cells PloS One. 2014 | Pubmed ID: 24714595 The Dynamics and Regulators of Cell Fate Decisions Are Revealed by Pseudotemporal Ordering of Single Cells Nature Biotechnology. Apr, 2014 | Pubmed ID: 24658644 Brief Report: Importance of SOX8 for in Vitro Chondrogenic Differentiation of Human Mesenchymal Stromal Cells Stem Cells (Dayton, Ohio). Jun, 2014 | Pubmed ID: 24449344 Genome-scale CRISPR-Cas9 Knockout Screening in Human Cells Science (New York, N.Y.). Jan, 2014 | Pubmed ID: 24336571 MicroRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACAN Stem Cells and Development. Feb, 2014 | Pubmed ID: 24063364 High-resolution Mapping Reveals a Conserved, Widespread, Dynamic MRNA Methylation Program in Yeast Meiosis Cell. Dec, 2013 | Pubmed ID: 24269006 Early B-cell Factor-1 (EBF1) is a Key Regulator of Metabolic and Inflammatory Signaling Pathways in Mature Adipocytes The Journal of Biological Chemistry. Dec, 2013 | Pubmed ID: 24174531 Cellular Source and Mechanisms of High Transcriptome Complexity in the Mammalian Testis Cell Reports. Jun, 2013 | Pubmed ID: 23791531 Systematic Dissection of Regulatory Motifs in 2000 Predicted Human Enhancers Using a Massively Parallel Reporter Assay Genome Research. May, 2013 | Pubmed ID: 23512712 Genome-wide Map of Quantified Epigenetic Changes During in Vitro Chondrogenic Differentiation of Primary Human Mesenchymal Stem Cells BMC Genomics. 2013 | Pubmed ID: 23414147 Convergent and Divergent Evolution of Genomic Imprinting in the Marsupial Monodelphis Domestica BMC Genomics. 2012 | Pubmed ID: 22899817 Integrative Genomics Identifies the Corepressor SMRT As a Gatekeeper of Adipogenesis Through the Transcription Factors C/EBPβ and KAISO Molecular Cell. May, 2012 | Pubmed ID: 22521691 A Unique Regulatory Phase of DNA Methylation in the Early Mammalian Embryo Nature. Apr, 2012 | Pubmed ID: 22456710 Systematic Dissection and Optimization of Inducible Enhancers in Human Cells Using a Massively Parallel Reporter Assay Nature Biotechnology. Mar, 2012 | Pubmed ID: 22371084 Mapping and Analysis of Chromatin State Dynamics in Nine Human Cell Types Nature. May, 2011 | Pubmed ID: 21441907 美国国家卫生研究院路线图表观遗传组映射财团。 Nature Biotechnology. Oct, 2010 | Pubmed ID: 20944595 小鼠和人类成脂比较 Epigenomic 分析。 Cell. Oct, 2010 | Pubmed ID: 20887899 基因组规模 DNA 甲基化的临床样本单核苷酸分辨率的映射。 Nature Methods. Feb, 2010 | Pubmed ID: 20062050 ZBED6,源自驯化的 DNA 转座子新型转录因子调节 IGF2 表达和肌肉生长。 PLoS Biology. Dec, 2009 | Pubmed ID: 20016685 染色质签名揭示了超过一千个高保守大非编码 Rna 在哺乳动物中。 Nature. Mar, 2009 | Pubmed ID: 19182780 全基因组分析的 PRC1 和 PRC2 占用标识双价域两类。 PLoS Genetics. Oct, 2008 | Pubmed ID: 18974828 DNA 甲基化基因组规模地图多能干和分化的细胞。 Nature. Aug, 2008 | Pubmed ID: 18600261 夹层综合基因组分析通过直接重新编程。 Nature. Jul, 2008 | Pubmed ID: 18509334 全基因组中多能干和沿袭犯细胞染色质状态的映射。 Nature. Aug, 2007 | Pubmed ID: 17603471 基因组袋单家蝇的揭示了非编码序列中的创新。 Nature. May, 2007 | Pubmed ID: 17495919 监管图案守恒地区的人类基因组,包括成千上万的 Ctcf 结构域绝缘子站点的系统发现。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2007 | Pubmed ID: 17442748 与变量分布在胎盘哺乳动物之中的第二个脂肪酸酰胺水解。 The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17015445 System-wide Genomic and Biochemical Comparisons of Sialic Acid Biology Among Primates and Rodents: Evidence for Two Modes of Rapid Evolution The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16769723 双价染色质结构标记关键发展基因在胚胎干细胞。 Cell. Apr, 2006 | Pubmed ID: 16630819 DNA 序列与人类染色体 8 分析。 Nature. Jan, 2006 | Pubmed ID: 16421571 基因组序列、 比较分析和国内狗的单体型结构。 Nature. Dec, 2005 | Pubmed ID: 16341006 选择 CCR5 Delta32 在这种情况。 PLoS Biology. Nov, 2005 | Pubmed ID: 16248677 DNA 序列与人类染色体 18 分析。 Nature. Sep, 2005 | Pubmed ID: 16177791 一个人特定基因的小胶质细胞。 Science (New York, N.Y.). Sep, 2005 | Pubmed ID: 16151003 Improving Genome Annotations Using Phylogenetic Profile Anomaly Detection Bioinformatics (Oxford, England). Feb, 2005 | Pubmed ID: 15374867 What Makes Us Human? Genome Biology. 2004 | Pubmed ID: 15287969 在培养的哺乳动物细胞大规模并行报告基因分析 Alexandre Melnikov1, Xiaolan Zhang1, Peter Rogov1, Li Wang1, Tarjei S. Mikkelsen1 1Broad Institute Biologie
在培养的哺乳动物细胞大规模并行报告基因分析 Alexandre Melnikov1, Xiaolan Zhang1, Peter Rogov1, Li Wang1, Tarjei S. Mikkelsen1 1Broad Institute Biologie