Tarjei S. Mikkelsen Broad Institute Biography Publications Institution JoVE Articles Tarjei S. Mikkelsen has not added a biography. If you are Tarjei S. Mikkelsen and would like to personalize this page please email our Author Liaison for assistance. Publications Perturbation of M6A Writers Reveals Two Distinct Classes of MRNA Methylation at Internal and 5' Sites Cell Reports. Jul, 2014 | Pubmed ID: 24981863 Comprehensive Mutational Scanning of a Kinase in Vivo Reveals Substrate-dependent Fitness Landscapes Nucleic Acids Research. Oct, 2014 | Pubmed ID: 24914046 The Regulatory Landscape of Osteogenic Differentiation Stem Cells (Dayton, Ohio). Jun, 2014 | Pubmed ID: 24898411 Analysis of the Effects of Five Factors Relevant to in Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput MRNA-profiling PloS One. 2014 | Pubmed ID: 24816923 ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myoblast Cells PloS One. 2014 | Pubmed ID: 24714595 The Dynamics and Regulators of Cell Fate Decisions Are Revealed by Pseudotemporal Ordering of Single Cells Nature Biotechnology. Apr, 2014 | Pubmed ID: 24658644 Brief Report: Importance of SOX8 for in Vitro Chondrogenic Differentiation of Human Mesenchymal Stromal Cells Stem Cells (Dayton, Ohio). Jun, 2014 | Pubmed ID: 24449344 Genome-scale CRISPR-Cas9 Knockout Screening in Human Cells Science (New York, N.Y.). Jan, 2014 | Pubmed ID: 24336571 MicroRNA-140 Targets RALA and Regulates Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Translational Enhancement of SOX9 and ACAN Stem Cells and Development. Feb, 2014 | Pubmed ID: 24063364 High-resolution Mapping Reveals a Conserved, Widespread, Dynamic MRNA Methylation Program in Yeast Meiosis Cell. Dec, 2013 | Pubmed ID: 24269006 Early B-cell Factor-1 (EBF1) is a Key Regulator of Metabolic and Inflammatory Signaling Pathways in Mature Adipocytes The Journal of Biological Chemistry. Dec, 2013 | Pubmed ID: 24174531 Cellular Source and Mechanisms of High Transcriptome Complexity in the Mammalian Testis Cell Reports. Jun, 2013 | Pubmed ID: 23791531 Systematic Dissection of Regulatory Motifs in 2000 Predicted Human Enhancers Using a Massively Parallel Reporter Assay Genome Research. May, 2013 | Pubmed ID: 23512712 Genome-wide Map of Quantified Epigenetic Changes During in Vitro Chondrogenic Differentiation of Primary Human Mesenchymal Stem Cells BMC Genomics. 2013 | Pubmed ID: 23414147 Convergent and Divergent Evolution of Genomic Imprinting in the Marsupial Monodelphis Domestica BMC Genomics. 2012 | Pubmed ID: 22899817 Integrative Genomics Identifies the Corepressor SMRT As a Gatekeeper of Adipogenesis Through the Transcription Factors C/EBPβ and KAISO Molecular Cell. May, 2012 | Pubmed ID: 22521691 A Unique Regulatory Phase of DNA Methylation in the Early Mammalian Embryo Nature. Apr, 2012 | Pubmed ID: 22456710 Systematic Dissection and Optimization of Inducible Enhancers in Human Cells Using a Massively Parallel Reporter Assay Nature Biotechnology. Mar, 2012 | Pubmed ID: 22371084 Mapping and Analysis of Chromatin State Dynamics in Nine Human Cell Types Nature. May, 2011 | Pubmed ID: 21441907 The NIH Roadmap Epigenomics Mapping Consortium Nature Biotechnology. Oct, 2010 | Pubmed ID: 20944595 Comparative Epigenomic Analysis of Murine and Human Adipogenesis Cell. Oct, 2010 | Pubmed ID: 20887899 Genome-scale DNA Methylation Mapping of Clinical Samples at Single-nucleotide Resolution Nature Methods. Feb, 2010 | Pubmed ID: 20062050 ZBED6, a Novel Transcription Factor Derived from a Domesticated DNA Transposon Regulates IGF2 Expression and Muscle Growth PLoS Biology. Dec, 2009 | Pubmed ID: 20016685 Chromatin Signature Reveals over a Thousand Highly Conserved Large Non-coding RNAs in Mammals Nature. Mar, 2009 | Pubmed ID: 19182780 Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains PLoS Genetics. Oct, 2008 | Pubmed ID: 18974828 Genome-scale DNA Methylation Maps of Pluripotent and Differentiated Cells Nature. Aug, 2008 | Pubmed ID: 18600261 Dissecting Direct Reprogramming Through Integrative Genomic Analysis Nature. Jul, 2008 | Pubmed ID: 18509334 Genome-wide Maps of Chromatin State in Pluripotent and Lineage-committed Cells Nature. Aug, 2007 | Pubmed ID: 17603471 Genome of the Marsupial Monodelphis Domestica Reveals Innovation in Non-coding Sequences Nature. May, 2007 | Pubmed ID: 17495919 Systematic Discovery of Regulatory Motifs in Conserved Regions of the Human Genome, Including Thousands of CTCF Insulator Sites Proceedings of the National Academy of Sciences of the United States of America. Apr, 2007 | Pubmed ID: 17442748 A Second Fatty Acid Amide Hydrolase with Variable Distribution Among Placental Mammals The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17015445 System-wide Genomic and Biochemical Comparisons of Sialic Acid Biology Among Primates and Rodents: Evidence for Two Modes of Rapid Evolution The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16769723 A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells Cell. Apr, 2006 | Pubmed ID: 16630819 DNA Sequence and Analysis of Human Chromosome 8 Nature. Jan, 2006 | Pubmed ID: 16421571 Genome Sequence, Comparative Analysis and Haplotype Structure of the Domestic Dog Nature. Dec, 2005 | Pubmed ID: 16341006 The Case for Selection at CCR5-Delta32 PLoS Biology. Nov, 2005 | Pubmed ID: 16248677 DNA Sequence and Analysis of Human Chromosome 18 Nature. Sep, 2005 | Pubmed ID: 16177791 A Human-specific Gene in Microglia Science (New York, N.Y.). Sep, 2005 | Pubmed ID: 16151003 Improving Genome Annotations Using Phylogenetic Profile Anomaly Detection Bioinformatics (Oxford, England). Feb, 2005 | Pubmed ID: 15374867 What Makes Us Human? Genome Biology. 2004 | Pubmed ID: 15287969 Massivt Parallelle Reporter Analyser i dyrkede pattedyrceller Alexandre Melnikov1, Xiaolan Zhang1, Peter Rogov1, Li Wang1, Tarjei S. Mikkelsen1 1Broad Institute Biologie
Massivt Parallelle Reporter Analyser i dyrkede pattedyrceller Alexandre Melnikov1, Xiaolan Zhang1, Peter Rogov1, Li Wang1, Tarjei S. Mikkelsen1 1Broad Institute Biologie