Wieland B. Huttner Max Planck Institute of Molecular Cell Biology and Genetics Biography Publications Institution JoVE Articles Wieland B. Huttner has not added a biography. If you are Wieland B. Huttner and would like to personalize this page please email our Author Liaison for assistance. Publications Response to Comment on "Human TKTL1 Implies Greater Neurogenesis in Frontal Neocortex of Modern Humans Than Neanderthals" Science (New York, N.Y.). Mar, 2023 | Pubmed ID: 36893240 Primary Cilia Are WNT-transducing Organelles Whose Biogenesis is Controlled by a WNT-PP1 Axis Developmental Cell. Jan, 2023 | Pubmed ID: 36693320 Human-specific Ensures Human-like Basal Progenitor Levels in Hominid Cerebral Organoids EMBO Reports. Sep, 2022 | Pubmed ID: 36381990 Human-specific ARHGAP11B Ensures Human-like Basal Progenitor Levels in Hominid Cerebral Organoids EMBO Reports. Nov, 2022 | Pubmed ID: 36098218 Human TKTL1 Implies Greater Neurogenesis in Frontal Neocortex of Modern Humans Than Neanderthals Science (New York, N.Y.). Sep, 2022 | Pubmed ID: 36074851 Longer Metaphase and Fewer Chromosome Segregation Errors in Modern Human Than Neanderthal Brain Development Science Advances. Jul, 2022 | Pubmed ID: 35905187 Progenitor-Based Cell Biological Aspects of Neocortex Development and Evolution Frontiers in Cell and Developmental Biology. 2022 | Pubmed ID: 35602606 What Are the Human-Specific Aspects of Neocortex Development? Frontiers in Neuroscience. 2022 | Pubmed ID: 35495057 From Stem and Progenitor Cells to Neurons in the Developing Neocortex: Key Differences Among Hominids The FEBS Journal. Mar, 2022 | Pubmed ID: 33638923 The Role of the Extracellular Matrix in Neural Progenitor Cell Proliferation and Cortical Folding During Human Neocortex Development Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 35140590 Primary Cilia and Centrosomes in Neocortex Development Frontiers in Neuroscience. 2021 | Pubmed ID: 34744618 H3 Acetylation Selectively Promotes Basal Progenitor Proliferation and Neocortex Expansion Science Advances. Sep, 2021 | Pubmed ID: 34524839 Mitotic WNT Signalling Orchestrates Neurogenesis in the Developing Neocortex The EMBO Journal. Oct, 2021 | Pubmed ID: 34431536 How Neural Stem Cells Contribute to Neocortex Development Biochemical Society Transactions. Nov, 2021 | Pubmed ID: 34397081 Generation of Interspecies Mouse-rat Chimeric Embryos by Embryonic Stem (ES) Cell Microinjection STAR Protocols. Jun, 2021 | Pubmed ID: 34189467 Tissue Culture Protocols for Studying the Developing Neocortex Bio-protocol. May, 2021 | Pubmed ID: 34150938 Neocortex Expansion in Development and Evolution-from Genes to Progenitor Cell Biology Current Opinion in Cell Biology. Dec, 2021 | Pubmed ID: 34098196 Human-Specific Genes, Cortical Progenitor Cells, and Microcephaly Cells. May, 2021 | Pubmed ID: 34063381 Length of the Neurogenic Period-A Key Determinant for the Generation of Upper-Layer Neurons During Neocortex Development and Evolution Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 34055808 Expression of Human-specific ARHGAP11B in Mice Leads to Neocortex Expansion and Increased Memory Flexibility The EMBO Journal. Jul, 2021 | Pubmed ID: 33938018 Sulfonated Cryogel Scaffolds for Focal Delivery in Ex-vivo Brain Tissue Cultures Biomaterials. Apr, 2021 | Pubmed ID: 33618220 Metabolic Regulation of Neocortical Expansion in Development and Evolution Neuron. Dec, 2020 | Pubmed ID: 33306962 Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex Neuron. Dec, 2020 | Pubmed ID: 33080227 Lengthening Neurogenic Period During Neocortical Development Causes a Hallmark of Neocortex Expansion Current Biology : CB. Nov, 2020 | Pubmed ID: 32888487 Basal Progenitor Morphology and Neocortex Evolution Trends in Neurosciences. 11, 2020 | Pubmed ID: 32828546 Corrigendum: Neurotransmitters As Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32733877 Transcriptional Regulators and Human-Specific/Primate-Specific Genes in Neocortical Neurogenesis International Journal of Molecular Sciences. Jun, 2020 | Pubmed ID: 32610533 Human-specific Increases Size and Folding of Primate Neocortex in the Fetal Marmoset Science (New York, N.Y.). 07, 2020 | Pubmed ID: 32554627 Neurotransmitters As Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32528958 Prominins Control Ciliary Length Throughout the Animal Kingdom: New Lessons from Human Prominin-1 and Zebrafish Prominin-3 The Journal of Biological Chemistry. May, 2020 | Pubmed ID: 32201384 Extracellular Matrix-inducing Sox9 Promotes Both Basal Progenitor Proliferation and Gliogenesis in Developing Neocortex ELife. Mar, 2020 | Pubmed ID: 32191207 A Truncating Aspm Allele Leads to a Complex Cognitive Phenotype and Region-specific Reductions in Parvalbuminergic Neurons Translational Psychiatry. Feb, 2020 | Pubmed ID: 32066665 Signs of Reduced Basal Progenitor Levels and Cortical Neurogenesis in Human Fetuses with Open Spina Bifida at 11-15 Weeks of Gestation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2020 | Pubmed ID: 31953373 Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis Neuron. Mar, 2020 | Pubmed ID: 31883789 Genetic Modification of Brain Organoids Frontiers in Cellular Neuroscience. 2019 | Pubmed ID: 31920558 Organoid Single-cell Genomic Atlas Uncovers Human-specific Features of Brain Development Nature. 10, 2019 | Pubmed ID: 31619793 Robotic Platform for Microinjection into Single Cells in Brain Tissue EMBO Reports. 10, 2019 | Pubmed ID: 31469223 The Golgi Apparatus in Polarized Neuroepithelial Stem Cells and Their Progeny: Canonical and Noncanonical Features Results and Problems in Cell Differentiation. 2019 | Pubmed ID: 31435803 Malformations of Human Neocortex in Development - Their Progenitor Cell Basis and Experimental Model Systems Frontiers in Cellular Neuroscience. 2019 | Pubmed ID: 31338027 The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or P300 Cancers. Jul, 2019 | Pubmed ID: 31324005 YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex Cell Reports. 04, 2019 | Pubmed ID: 31018127 Transport, Metabolism, and Function of Thyroid Hormones in the Developing Mammalian Brain Frontiers in Endocrinology. 2019 | Pubmed ID: 31001205 How the Extracellular Matrix Shapes Neural Development Open Biology. 01, 2019 | Pubmed ID: 30958121 Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology Cell Stem Cell. 04, 2019 | Pubmed ID: 30905618 The Centrosome Protein AKNA Regulates Neurogenesis Via Microtubule Organization Nature. 03, 2019 | Pubmed ID: 30787442 Primate Neocortex Development and Evolution: Conserved Versus Evolved Folding The Journal of Comparative Neurology. 07, 2019 | Pubmed ID: 30552689 Prominin-1 Controls Stem Cell Activation by Orchestrating Ciliary Dynamics The EMBO Journal. Jan, 2019 | Pubmed ID: 30523147 Prominin-1 (CD133) Modulates the Architecture and Dynamics of Microvilli Traffic (Copenhagen, Denmark). 01, 2019 | Pubmed ID: 30328220 Human-specific Induces Hallmarks of Neocortical Expansion in Developing Ferret Neocortex ELife. 11, 2018 | Pubmed ID: 30484771 A Novel Population of Hopx-dependent Basal Radial Glial Cells in the Developing Mouse Neocortex Development (Cambridge, England). 10, 2018 | Pubmed ID: 30266827 Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex Neuron. 08, 2018 | Pubmed ID: 30078576 Brain Organoids As Models to Study Human Neocortex Development and Evolution Current Opinion in Cell Biology. 12, 2018 | Pubmed ID: 30006054 Epigenetic and Transcriptional Pre-patterning-An Emerging Theme in Cortical Neurogenesis Frontiers in Neuroscience. 2018 | Pubmed ID: 29896084 Evolution and Cell-type Specificity of Human-specific Genes Preferentially Expressed in Progenitors of Fetal Neocortex ELife. 03, 2018 | Pubmed ID: 29561261 Insm1 Induces Neural Progenitor Delamination in Developing Neocortex Via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7 Neuron. 03, 2018 | Pubmed ID: 29503187 Novel Gene Function and Regulation in Neocortex Expansion Current Opinion in Cell Biology. 12, 2017 | Pubmed ID: 29227861 Epigenome Profiling and Editing of Neocortical Progenitor Cells During Development The EMBO Journal. 09, 2017 | Pubmed ID: 28765163 A Tunable Refractive Index Matching Medium for Live Imaging Cells, Tissues and Model Organisms ELife. 07, 2017 | Pubmed ID: 28708059 Human-specific Genomic Signatures of Neocortical Expansion Current Opinion in Neurobiology. 02, 2017 | Pubmed ID: 27912138 Neural Progenitor Cells and Their Role in the Development and Evolutionary Expansion of the Neocortex Wiley Interdisciplinary Reviews. Developmental Biology. 01, 2017 | Pubmed ID: 27865053 A Single Splice Site Mutation in Human-specific Causes Basal Progenitor Amplification Science Advances. Dec, 2016 | Pubmed ID: 27957544 Monoclonal Antibodies 13A4 and AC133 Do Not Recognize the Canine Ortholog of Mouse and Human Stem Cell Antigen Prominin-1 (CD133) PloS One. 2016 | Pubmed ID: 27701459 Differences and Similarities Between Human and Chimpanzee Neural Progenitors During Cerebral Cortex Development ELife. 09, 2016 | Pubmed ID: 27669147 ASPM and CITK Regulate Spindle Orientation by Affecting the Dynamics of Astral Microtubules EMBO Reports. 10, 2016 | Pubmed ID: 27562601 Neocortex Expansion in Development and Evolution - from Cell Biology to Single Genes Current Opinion in Neurobiology. 08, 2016 | Pubmed ID: 27258840 GEMC1 is a Critical Regulator of Multiciliated Cell Differentiation The EMBO Journal. 05, 2016 | Pubmed ID: 26933123 Comment on "Cortical Folding Scales Universally with Surface Area and Thickness, Not Number of Neurons" Science (New York, N.Y.). Feb, 2016 | Pubmed ID: 26912886 Relief of Hypoxia by Angiogenesis Promotes Neural Stem Cell Differentiation by Targeting Glycolysis The EMBO Journal. May, 2016 | Pubmed ID: 26856890 CRISPR/Cas9-induced Disruption of Gene Expression in Mouse Embryonic Brain and Single Neural Stem Cells in Vivo EMBO Reports. Mar, 2016 | Pubmed ID: 26758805 Abnormal Spindle-like Microcephaly-associated (ASPM) Mutations Strongly Disrupt Neocortical Structure but Spare the Hippocampus and Long-term Memory Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. Jan, 2016 | Pubmed ID: 26691732 S-phase Duration is the Main Target of Cell Cycle Regulation in Neural Progenitors of Developing Ferret Neocortex The Journal of Comparative Neurology. Feb, 2016 | Pubmed ID: 25963823 Human Cerebral Organoids Recapitulate Gene Expression Programs of Fetal Neocortex Development Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015 | Pubmed ID: 26644564 Novel Insights into Mammalian Embryonic Neural Stem Cell Division: Focus on Microtubules Molecular Biology of the Cell. Dec, 2015 | Pubmed ID: 26628750 Lipidome of Midbody Released from Neural Stem and Progenitor Cells During Mammalian Cortical Neurogenesis Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26379497 Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex PLoS Biology. Aug, 2015 | Pubmed ID: 26252244 Neurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution PloS One. 2015 | Pubmed ID: 26134977 Stem Cells: Slow and Steady Wins the Race Nature Neuroscience. May, 2015 | Pubmed ID: 25919957 Analysis of Primary Cilia in the Developing Mouse Brain Methods in Cell Biology. 2015 | Pubmed ID: 25837388 Human-specific Gene ARHGAP11B Promotes Basal Progenitor Amplification and Neocortex Expansion Science (New York, N.Y.). Mar, 2015 | Pubmed ID: 25721503 An Adaptive Threshold in Mammalian Neocortical Evolution PLoS Biology. Nov, 2014 | Pubmed ID: 25405475 The Role of α-E-catenin in Cerebral Cortex Development: Radial Glia Specific Effect on Neuronal Migration Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25147501 The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex Annual Review of Cell and Developmental Biology. 2014 | Pubmed ID: 25000993 Specific Polar Subpopulations of Astral Microtubules Control Spindle Orientation and Symmetric Neural Stem Cell Division ELife. Jul, 2014 | Pubmed ID: 24996848 Human Prominin-1 (CD133) is Detected in Both Neoplastic and Non-neoplastic Salivary Gland Diseases and Released into Saliva in a Ubiquitinated Form PloS One. 2014 | Pubmed ID: 24911657 Neural Progenitors, Neurogenesis and the Evolution of the Neocortex Development (Cambridge, England). Jun, 2014 | Pubmed ID: 24866113 Microinjection of Membrane-impermeable Molecules into Single Neural Stem Cells in Brain Tissue Nature Protocols. May, 2014 | Pubmed ID: 24762784 3' UTR-dependent, MiR-92-mediated Restriction of Tis21 Expression Maintains Asymmetric Neural Stem Cell Division to Ensure Proper Neocortex Size Cell Reports. Apr, 2014 | Pubmed ID: 24726360 Neurogenesis During Development of the Vertebrate Central Nervous System EMBO Reports. Apr, 2014 | Pubmed ID: 24639559 Integrin αvβ3 and Thyroid Hormones Promote Expansion of Progenitors in Embryonic Neocortex Development (Cambridge, England). Feb, 2014 | Pubmed ID: 24496617 Progenitor Networking in the Fetal Primate Neocortex Neuron. Oct, 2013 | Pubmed ID: 24139029 Asymmetric Inheritance of Centrosome-associated Primary Cilium Membrane Directs Ciliogenesis After Cell Division Cell. Oct, 2013 | Pubmed ID: 24120134 Conical Expansion of the Outer Subventricular Zone and the Role of Neocortical Folding in Evolution and Development Frontiers in Human Neuroscience. 2013 | Pubmed ID: 23914167 The Secondary Loss of Gyrencephaly As an Example of Evolutionary Phenotypical Reversal Frontiers in Neuroanatomy. 2013 | Pubmed ID: 23805079 Prominin-1 (CD133) and the Cell Biology of Neural Progenitors and Their Progeny Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23161077 Transcriptomes of Germinal Zones of Human and Mouse Fetal Neocortex Suggest a Role of Extracellular Matrix in Progenitor Self-renewal Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22753484 Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix Jacchus Cerebral Cortex (New York, N.Y. : 1991). Feb, 2012 | Pubmed ID: 22114084 Basolateral Rather Than Apical Primary Cilia on Neuroepithelial Cells Committed to Delamination Development (Cambridge, England). Jan, 2012 | Pubmed ID: 22096071 A New Approach to Manipulate the Fate of Single Neural Stem Cells in Tissue Nature Neuroscience. Dec, 2011 | Pubmed ID: 22179113 Proliferating Versus Differentiating Stem and Cancer Cells Exhibit Distinct Midbody-release Behaviour Nature Communications. Oct, 2011 | Pubmed ID: 22009035 Neural Stem and Progenitor Cells Shorten S-phase on Commitment to Neuron Production Nature Communications. Jan, 2011 | Pubmed ID: 21224845 Cortical Progenitor Expansion, Self-renewal and Neurogenesis-a Polarized Perspective Current Opinion in Neurobiology. Feb, 2011 | Pubmed ID: 21036598 Prominin-1 (CD133) is Not Restricted to Stem Cells Located in the Basal Compartment of Murine and Human Prostate The Prostate. Feb, 2011 | Pubmed ID: 20717901 Neural Progenitor Nuclei IN Motion Neuron. Sep, 2010 | Pubmed ID: 20869589 Mutations in Mouse Aspm (abnormal Spindle-like Microcephaly Associated) Cause Not Only Microcephaly but Also Major Defects in the Germline Proceedings of the National Academy of Sciences of the United States of America. Sep, 2010 | Pubmed ID: 20823249 OSVZ Progenitors of Human and Ferret Neocortex Are Epithelial-like and Expand by Integrin Signaling Nature Neuroscience. Jun, 2010 | Pubmed ID: 20436478 Tis21 Expression Marks Not Only Populations of Neurogenic Precursor Cells but Also New Postmitotic Neurons in Adult Hippocampal Neurogenesis Cerebral Cortex (New York, N.Y. : 1991). Feb, 2010 | Pubmed ID: 19482889 Autonomic Function in Hypertension; Role of Genetic Variation at the Catecholamine Storage Vesicle Protein Chromogranin B Circulation. Cardiovascular Genetics. Feb, 2009 | Pubmed ID: 20011129 Myosin II is Required for Interkinetic Nuclear Migration of Neural Progenitors Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805325 Cdk4/cyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors Cell Stem Cell. Sep, 2009 | Pubmed ID: 19733543 Ablation of Cholesterol Biosynthesis in Neural Stem Cells Increases Their VEGF Expression and Angiogenesis but Causes Neuron Apoptosis Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19416849 Nonselective Sister Chromatid Segregation in Mouse Embryonic Neocortical Precursor Cells Cerebral Cortex (New York, N.Y. : 1991). Jul, 2009 | Pubmed ID: 19342402 Release of Extracellular Membrane Vesicles from Microvilli of Epithelial Cells is Enhanced by Depleting Membrane Cholesterol FEBS Letters. Mar, 2009 | Pubmed ID: 19302789 MiRNAs Are Essential for Survival and Differentiation of Newborn Neurons but Not for Expansion of Neural Progenitors During Early Neurogenesis in the Mouse Embryonic Neocortex Development (Cambridge, England). Dec, 2008 | Pubmed ID: 18997113 Cytokinesis of Neuroepithelial Cells Can Divide Their Basal Process Before Anaphase The EMBO Journal. Dec, 2008 | Pubmed ID: 18971946 Insulinoma-associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex Neuron. Oct, 2008 | Pubmed ID: 18940587 The Cell Biology of Neural Stem and Progenitor Cells and Its Significance for Their Proliferation Versus Differentiation During Mammalian Brain Development Current Opinion in Cell Biology. Dec, 2008 | Pubmed ID: 18930817 Making Bigger Brains-the Evolution of Neural-progenitor-cell Division Journal of Cell Science. Sep, 2008 | Pubmed ID: 18716282 Live Imaging at the Onset of Cortical Neurogenesis Reveals Differential Appearance of the Neuronal Phenotype in Apical Versus Basal Progenitor Progeny PloS One. 2008 | Pubmed ID: 18545663 Neuronal and Glial Cell Biology Current Opinion in Neurobiology. Oct, 2007 | Pubmed ID: 18093823 On the Origin of Neurons Genome Biology. 2007 | Pubmed ID: 17666121 Cell Polarity from Cell Division Developmental Cell. May, 2007 | Pubmed ID: 17488617 Midbody and Primary Cilium of Neural Progenitors Release Extracellular Membrane Particles Enriched in the Stem Cell Marker Prominin-1 The Journal of Cell Biology. Feb, 2007 | Pubmed ID: 17283184 Single-cell Detection of MicroRNAs in Developing Vertebrate Embryos After Acute Administration of a Dual-fluorescence Reporter/sensor Plasmid BioTechniques. Dec, 2006 | Pubmed ID: 17191618 Aspm Specifically Maintains Symmetric Proliferative Divisions of Neuroepithelial Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16798874 Tyrosine O-sulfation Current Protocols in Protein Science. Mar, 2005 | Pubmed ID: 18429275 Symmetric Versus Asymmetric Cell Division During Neurogenesis in the Developing Vertebrate Central Nervous System Current Opinion in Cell Biology. Dec, 2005 | Pubmed ID: 16243506 Selective Lengthening of the Cell Cycle in the Neurogenic Subpopulation of Neural Progenitor Cells During Mouse Brain Development The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2005 | Pubmed ID: 16014714 Release of Extracellular Membrane Particles Carrying the Stem Cell Marker Prominin-1 (CD133) from Neural Progenitors and Other Epithelial Cells Journal of Cell Science. Jul, 2005 | Pubmed ID: 15976444 Identification of Novel Prominin-1/CD133 Splice Variants with Alternative C-termini and Their Expression in Epididymis and Testis Journal of Cell Science. Aug, 2004 | Pubmed ID: 15316084 Asymmetric Distribution of the Apical Plasma Membrane During Neurogenic Divisions of Mammalian Neuroepithelial Cells The EMBO Journal. Jun, 2004 | Pubmed ID: 15141162 Tissue-specific RNA Interference in Post-implantation Mouse Embryos Using Directional Electroporation and Whole Embryo Culture Differentiation; Research in Biological Diversity. Mar, 2004 | Pubmed ID: 15066189 Neurons Arise in the Basal Neuroepithelium of the Early Mammalian Telencephalon: a Major Site of Neurogenesis Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14963232 An Inhibition of Cyclin-dependent Kinases That Lengthens, but Does Not Arrest, Neuroepithelial Cell Cycle Induces Premature Neurogenesis Journal of Cell Science. Dec, 2003 | Pubmed ID: 14625388 AC133 Antigen, CD133, Prominin-1, Prominin-2, Etc.: Prominin Family Gene Products in Need of a Rational Nomenclature Stem Cells (Dayton, Ohio). 2003 | Pubmed ID: 12832703 Characterization of Prominin-2, a New Member of the Prominin Family of Pentaspan Membrane Glycoproteins The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12514187 Tissue-specific RNA Interference in Postimplantation Mouse Embryos with Endoribonuclease-prepared Short Interfering RNA Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12391321 Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification (Video) | JoVE Lidiia Tynianskaia1, Nesil Eşiyok1, Wieland B. Huttner2, Michael Heide1,2 1German Primate Center, Leibniz Institute for Primate Research, 2Max Planck Institute of Molecular Cell Biology and Genetics JoVE 65176 Entwicklungsbiologie Manipulation af enkelt neurale stamceller og neuroner i hjernen skiver ved hjælp af Robotic Microinjection Gabriella Shull*1,2, Christiane Haffner*3, Wieland B. Huttner3, Elena Taverna3,4, Suhasa B. Kodandaramaiah1,5,6 1Department of Biomedical Engineering, University of Minnesota, 2Department of Biomedical Engineering, Duke University, 3Max Planck Institute of Molecular Cell Biology and Genetics, 4Max Planck Institute for Evolutionary Anthropology, 5Department of Mechanical Engineering, University of Minnesota, 6Graduate Program in Neuroscience, University of Minnesota JoVE 61599 Biotechnik
Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification (Video) | JoVE Lidiia Tynianskaia1, Nesil Eşiyok1, Wieland B. Huttner2, Michael Heide1,2 1German Primate Center, Leibniz Institute for Primate Research, 2Max Planck Institute of Molecular Cell Biology and Genetics JoVE 65176 Entwicklungsbiologie
Manipulation af enkelt neurale stamceller og neuroner i hjernen skiver ved hjælp af Robotic Microinjection Gabriella Shull*1,2, Christiane Haffner*3, Wieland B. Huttner3, Elena Taverna3,4, Suhasa B. Kodandaramaiah1,5,6 1Department of Biomedical Engineering, University of Minnesota, 2Department of Biomedical Engineering, Duke University, 3Max Planck Institute of Molecular Cell Biology and Genetics, 4Max Planck Institute for Evolutionary Anthropology, 5Department of Mechanical Engineering, University of Minnesota, 6Graduate Program in Neuroscience, University of Minnesota JoVE 61599 Biotechnik