Pressure Head-driven Flow

Pressure head-driven flow is the movement of a fluid caused by a difference in pressure expressed as an equivalent fluid-column height, a principle that links fluid mechanics to transport in bioengineering. The pressure-head gradient creates a driving force, and fluid moves from higher to lower total head through channels, porous materials, or tubing; resistance from viscosity and geometry determines the resulting flow rate. This framework helps analyze perfusion systems, microfluidic devices, filtration, and flow through biological tissues, supporting the design of laboratory models and biomedical devices and the interpretation of how pressure differences regulate fluid transport.

Pressure Head-driven Flow - Related Videos

Research

JoVE Journal - Engineering

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Cited by 4 •

2013

In this video we first describe fabrication and operation procedures of a surface acoustic wave (SAW) acoustic counterflow device. We then demonstrate an experimental setup that allows for both qualitative flow visualization and quantitative analysis of complex flows within the SAW pumping device.

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

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Cited by 5 •

2013

The laser heated diamond anvil cell combined with synchrotron micro-diffraction techniques allows researchers to explore the nature and properties of new phases of matter at extreme pressure and temperature (PT) conditions. Heterogeneous samples can be characterized in situ under high pressure by 2D mapping and combined powder, single-crystal and multigrain diffraction approaches.

Education

JoVE Science Education - Engineering

Cross Cylindrical Flow: Measuring Pressure Distribution and Estimating Drag Coefficients

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2023

Source: David Guo, College of Engineering, Technology, and Aeronautics (CETA), Southern New Hampshire University (SNHU), Manchester, New Hampshire The pressure distributions and drag estimations for cross cylindrical flow have been investigated for centuries. By ideal inviscid potential flow theory, the pressure distribution around a cylinder is vertically symmetric. The pressure distribution upstream and downstream of the cylinder is also symmetric, which results in a zero-net drag force.

Generating a Closed-Head Mild Traumatic Brain Injury in a Murine Model

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2025

Source: Logsdon, A. F., et al. Low-intensity Blast Wave Model for Preclinical Assessment of Closed-head Mild Traumatic Brain Injury in Rodents. J. Vis. Exp. (2020)This video demonstrates the induction of closed-head mild traumatic brain injury in a mouse model using a pressurized gas shock tube setup. The generated pressure wave ruptures the polyester membrane, delivering a shockwave to the mouse’s head that results in rapid brain movement within the skull, causing a mild traumatic brain injury.

Research

JoVE Journal - Chemistry
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Light-driven Enzymatic Decarboxylation

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Cited by 6 •

2016

We describe a protocol for the light-catalyzed generation of hydrogen peroxide — a cofactor for oxidative transformations.

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