Lowest Magnification
Lowest Magnification - Related Videos
08:41
Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
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Cited by 1 •
2025
Here, we present a versatile equibiaxial stretching device that is pneumatically actuated and compatible with high-resolution microscopy.
09:30
Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes
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Cited by 8 •
2019
Clinical translation of exosome-derived biomarkers for diseased and malignant cells is hindered by the lack of rapid and accurate quantification methods. This report describes the use of low-magnification dark-field microscope images to quantify specific exosome subtypes in small volume serum or plasma samples.
07:01
Impression Cytology of the Lid Wiper Area
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Cited by 3 •
2016
We collected, stained and imaged cells from the conjunctiva of the inner eyelid margin of human subjects. By characterizing cell morphology and metabolic activity, this method may further our understanding of dry eye and the role that friction between the ocular surfaces may play in perceiving ocular discomfort.
07:31
Microbial and Fungal Diversity - Student Protocol
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2019
Examining Microbial Colony Structures ExpandTo begin, collect your allocated culture plates and then remove the Parafilm and lid from one of them. Place the uncovered plate under a dissecting microscope and then observe the individual communities within each quadrant of the plate. As the colonies are identified, fill out the observed colony properties in the appropriate column in the table. Click Here to download Table 1 Then, repeat the observations for each of the other two bacterial species.
08:35
Introduction to Light Microscopy
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2023
The light microscope is an instrument used by researchers in many different fields to magnify specimens to as much as a thousand times their original size. In its simplest form, it is composed of a clear lens that magnifies the sample and a light source to illuminate it. However, most light microscopes are much more complex and house numerous fine-tuned lenses with tightly controlled dimensions all within the body of the microscope itself and in components such as the objectives and eyepieces.
FAQs
The broad view helps the observer understand how biological material is arranged across the slide before focusing on smaller features. It can reveal the specimen’s overall tissue or organism structure and makes it easier to decide which region deserves closer examination. This initial survey supports more efficient movement from general observation to detailed study.
At the lowest magnification, the wider field of view shows a larger portion of the specimen, while the greater working distance leaves more space between the objective lens and the slide. Together, these characteristics make orientation and region selection easier. They are especially useful when the important biological feature has not yet been located.
The lowest setting emphasizes coverage of the specimen, whereas higher settings are used to inspect progressively smaller structures such as cells or organelles. Increasing magnification narrows the area being viewed, so the observer may lose the broader structural context. Starting low therefore helps connect detailed observations with the specimen’s overall organization.
It allows the observer to scan a larger area and identify a suitable region before switching to a stronger objective. This is important when biological material is distributed across the slide or when only one area contains the structure of interest. Selecting the region first reduces the chance of examining an uninformative field at higher magnification.
Begin by examining the specimen broadly, then identify and center the region that requires closer study. After that, increase magnification to investigate cellular, organelle, or other fine details. Keeping the specimen positioned and the image focused as effectively as possible during the change helps preserve the selected area for continued observation.
They would use it when first orienting themselves on a biological slide, surveying tissue or an organism, or choosing a field for detailed examination. The setting is valuable in both learning and research because it links large-scale organization with later observations of cells and organelles, helping users interpret detail within the specimen’s broader context.