Auto-cho Software

Auto-CHO software is a specialized chemistry tool for analyzing carbohydrate structures, helping researchers interpret complex molecular information more efficiently. It supports structural assignment by organizing experimental nuclear magnetic resonance data and matching characteristic signal patterns to sugar residues, anomeric configurations, and glycosidic linkages. By reducing repetitive manual analysis, Auto-CHO can aid the characterization of oligosaccharides and related compounds, where overlapping resonances and numerous possible connectivities complicate interpretation. The software is relevant to carbohydrate chemistry, natural-product research, glycomics, and the development of reproducible workflows for identifying and comparing biologically important glycans.

Auto-cho Software - Related Videos

Research

JoVE Journal - Cancer Research

Tumor Allotransplantation in Drosophila melanogaster with a Programmable Auto-Nanoliter Injector

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Cited by 10 •

2021

This protocol provides detailed guidance for the initial and continued generational allotransplantation of Drosophila tumors into the abdomen of adult hosts for studying various aspects of neoplasia. Using an autoinjector apparatus, researchers can achieve improved efficiency and tumor yields compared to those achieved by traditional, manual methods.

Research

JoVE Journal - Bioengineering
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Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

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Cited by 11 •

2018

A detailed protocol for the concurrent operation of 48 parallel cell cultures under varied conditions in a microbioreactor system is presented. Cell culture process, harvest and subsequent antibody titer analysis are described.

Education

JoVE Core - Organic Chemistry

meta-Directing Deactivators: –NO2, –CN, –CHO, –⁠CO2R, –COR, –CO2H

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2023

All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for the...

VisualEyes: A Modular Software System for Oculomotor Experimentation

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Cited by 28 •

2011

Neural control and cognitive processes can be studied through eye movements. The VisualEyes software allows an operator to program stimuli on two computer screens independently using a simple, custom scripting language. The system can stimulate tandem eye movements (saccades and smooth pursuit) or opposing eye movements (vergence) or any combination.

Evaluating Skilled Prehension in Mice Using an Auto-Trainer

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Cited by 1 •

2019

Method to assess the impact of training on motor skills is a useful tool. Unfortunately, most behavioral assessments can be labor intensive and/or expensive.We describe here a robotic method of assessing prehension (reach-to-grasp) skill in mice.

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