Lung Abscess

A lung abscess is a localized, pus-filled cavity within lung tissue caused by infection and tissue destruction, making it an important cause of persistent fever, cough, and respiratory illness. It commonly develops when bacteria enter the lower airways, often after aspiration, and trigger inflammation, necrosis, and liquefaction that form a cavity that may drain into a bronchus. Clinical evaluation combines symptoms, microbiological testing, and chest imaging, particularly computed tomography, to distinguish an abscess from other cavitary lesions. Prolonged antibiotic therapy is the primary treatment, while drainage or surgery may be required for large, persistent, or complicated abscesses.

Lung Abscess - Related Videos

Education

JoVE Core - Pathophysiology

Brain Abscess l: Introduction

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2026

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Research

JoVE Journal - Medicine

A Simple Method of Mouse Lung Intubation

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Cited by 50 •

2013

This paper describes a striaghforward and efficient method of intubating mice for pulmonary function measurements or pulmonary instillation, that allows the mice to recover and be studied at later times. The procedure involves an inexpensive fiberoptic light source that directly illuminates the trachea.

Posterior Approach for Debridement of the Psoas Abscess

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2020

This is a cadaveric study investigating the landmarks for the posterior approach for irrigation and debridement of the psoas abscess. The interval between the transverse processes (TP) was used to access the substance of the psoas muscle.

Lung Capacity

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2019

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures. There are four defined lung volume measures: tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume. Tidal volume is the amount of air inhaled and exhaled in a normal breath. Inspiratory...

Lung Instillation and Fixation: Introducing Liquid into the Trachea and Fixing Lungs to Measure the Fixed Lung Volume

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2023

This video describes a simple and reliable method of introducing liquid into the trachea for lung instillation, fixation, and lung volume measurement.

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