Nissen Fundoplication
Nissen Fundoplication - Related Videos
08:21
Utilizing a 3D Printed Laparoscopic Nissen Fundoplication Model to Shorten a Resident's Learning Curve
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2025
This study describes how 3D printed models effectively accelerate the rate at which advanced laparoscopic surgery skills used in Nissen Fundoplication are mastered by surgical residents during residency training, thereby enhancing future preparedness.
11:19
Robotic Myotomy and Partial Fundoplication for Achalasia
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2023
Surgical myotomy with a partial fundoplication may be used in selected patients as a definitive treatment for achalasia. This article provides a step-by-step description of a robotic myotomy and partial fundoplication in a 32-year-old patient with megaesophagus.
11:28
Culturing Microglia from the Neonatal and Adult Central Nervous System
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Cited by 35 •
2013
We outline methods for the efficient and quick isolation/culture of viable microglia from the neonatal cerebral cortex and adult spinal cord. The dissection and plating of cortical microglia can be accomplished within 90 minutes, with the subsequent microglial harvest taking place ~ 10 days following the initial dissection.
14:45
Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
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Cited by 14 •
2012
In this report, we demonstrate the staining and analysis steps of a phenotyping assay performed on fresh whole blood to enumerate major innate and adaptive leukocyte populations. We emphasize considerations for performing these procedures in the context of a multicenter clinical trial.
FAQs
The fundus is positioned completely around the lower esophagus, adding support to the lower esophageal sphincter. This reinforced junction creates a stronger barrier between the stomach and esophagus, helping limit the upward movement associated with acid reflux and regurgitation. The mechanism is therefore anatomical: changing the relationship between the upper stomach and distal esophagus improves barrier function.
A complete wrap changes the anatomy at the junction between the esophagus and stomach, so its effects on swallowing and gastric venting require clinical attention. These functions are important when assessing how the repaired barrier performs in practice. Considering them alongside reflux control helps clinicians evaluate whether the procedure achieves its intended benefit without overlooking other relevant postoperative effects.
An associated hiatal hernia may be repaired during the same operation as the fundic wrap. Addressing both conditions is relevant because the procedure aims to strengthen the barrier at the esophagogastric junction, while the hernia represents an anatomical problem in that region. Surgical planning therefore considers the junction as a whole rather than focusing only on reflux symptoms.
The operation is commonly performed laparoscopically, with the upper stomach used to reinforce the lower esophageal sphincter. When necessary, the surgical plan also includes repair of an associated hiatal hernia. Understanding the anatomy of the fundus, lower esophagus, and junctional barrier is central to clinical training because these structures determine how the reconstruction is organized.
Clinicians may consider Nissen fundoplication when medication does not provide adequate relief from gastroesophageal reflux disease. The decision is linked to persistent clinical problems such as acid reflux, regurgitation, or esophageal irritation. Patient selection therefore requires attention to symptom control and the anatomical suitability of reinforcing the barrier between the stomach and esophagus.
Postoperative evaluation considers whether acid reflux, regurgitation, and esophageal irritation have been reduced, while also examining effects on swallowing and gastric venting. These outcomes reflect both the intended antireflux benefit and the functional consequences of changing the esophagogastric junction. Reviewing anatomy, operative steps, and clinical effects supports a more complete assessment of surgical success.